Leveraging cross-species transcription factor binding site patterns: from diabetes risk loci to disease mechanisms.
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FTO Obesity Variant Circuitry and Adipocyte Browning in HumansWhat induces watts in WAT?New insights from monogenic diabetes for "common" type 2 diabetesImmunological Response to Single Pathogen Challenge with Agents of the Bovine Respiratory Disease Complex: An RNA-Sequence Analysis of the Bronchial Lymph Node TranscriptomeThe short and long of noncoding sequences in the control of vascular cell phenotypesThe Effects of Sequence Variation on Genome-wide NRF2 Binding--New Target Genes and Regulatory SNPsTrans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin.GREGOR: evaluating global enrichment of trait-associated variants in epigenomic features using a systematic, data-driven approachThe genetic architecture of type 2 diabetesAllele-specific quantitative proteomics unravels molecular mechanisms modulated by cis-regulatory PPARG locus variation.Decoding the complex genetic causes of heart diseases using systems biologyFunctional annotation of Alzheimer's disease associated loci revealed by GWASs.Purifying selection in deeply conserved human enhancers is more consistent than in coding sequences.Thiazolidinediones and the promise of insulin sensitization in type 2 diabetes.Enhancer variants: evaluating functions in common disease.Approaches for establishing the function of regulatory genetic variants involved in disease.Multi-species, multi-transcription factor binding highlights conserved control of tissue-specific biological pathways.Genetic Variation Determines PPARγ Function and Anti-diabetic Drug Response In Vivo.Computational Characterization of Osteoporosis Associated SNPs and Genes Identified by Genome-Wide Association StudiesSystematic Functional Dissection of Common Genetic Variation Affecting Red Blood Cell TraitsMonogenic Diabetes: What It Teaches Us on the Common Forms of Type 1 and Type 2 Diabetes.Pain, Genes, and Function in the Post-Hip Fracture PeriodExplaining the disease phenotype of intergenic SNP through predicted long range regulation.Prospective functional classification of all possible missense variants in PPARG.Connecting genetic risk to disease end points through the human blood plasma proteomeDUBs, the regulation of cell identity and disease.Computational analyses of type 2 diabetes-associated loci identified by genome-wide association studies.Mechanisms of Type 2 Diabetes Risk Loci.Prioritising Causal Genes at Type 2 Diabetes Risk Loci.A data-driven modeling approach to identify disease-specific multi-organ networks driving physiological dysregulation10 Years of GWAS Discovery: Biology, Function, and Translation.An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.Common and rare forms of diabetes mellitus: towards a continuum of diabetes subtypes.Pharmacogenetics: Implications for Modern Type 2 Diabetes Therapy.Dissecting neural differentiation regulatory networks through epigenetic footprinting.Epigenomic and transcriptional control of insulin resistance.The Importance of Context: Uncovering Species- and Tissue-Specific Effects of Genetic Risk Variants for Type 2 Diabetes.Noncoding Genome-Wide Association Studies Variant for Obesity: Inroads Into Mechanism: An Overview From the AHA's Council on Functional Genomics and Translational Biology.Genetic Associations of Obesity: The Fat-Mass and Obesity-Associated (FTO) Gene.Commentary: FTO obesity variant circuitry and adipocyte browning in humans
P2860
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P2860
Leveraging cross-species transcription factor binding site patterns: from diabetes risk loci to disease mechanisms.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Leveraging cross-species trans ...... sk loci to disease mechanisms.
@en
Leveraging cross-species trans ...... sk loci to disease mechanisms.
@nl
type
label
Leveraging cross-species trans ...... sk loci to disease mechanisms.
@en
Leveraging cross-species trans ...... sk loci to disease mechanisms.
@nl
prefLabel
Leveraging cross-species trans ...... sk loci to disease mechanisms.
@en
Leveraging cross-species trans ...... sk loci to disease mechanisms.
@nl
P2093
P50
P1433
P1476
Leveraging cross-species trans ...... sk loci to disease mechanisms.
@en
P2093
Bernhard Horsthemke
Bernward Klocke
Christoph Hoffmann
DIAGRAM+Consortium
Derek Spieler
Gunnar Mellgren
Hans Hauner
Heekyoung Lee
Helene Riess
Kerstin Ehlers
P304
P356
10.1016/J.CELL.2013.10.058
P407
P50
P577
2014-01-01T00:00:00Z