Bexarotene blocks calcium-permeable ion channels formed by neurotoxic Alzheimer's β-amyloid peptides.
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Amyloid-beta Alzheimer targets - protein processing, lipid rafts, and amyloid-beta poresInhibition of IAPP Aggregation and Toxicity by Natural Products and DerivativesComparison of the amyloid pore forming properties of rat and human Alzheimer's beta-amyloid peptide 1-42: Calcium imaging dataAnalysis of differential secondary effects of novel rexinoids: select rexinoid X receptor ligands demonstrate differentiated side effect profiles.An anticancer drug suppresses the primary nucleation reaction that initiates the production of the toxic Aβ42 aggregates linked with Alzheimer's disease.A mirror code for protein-cholesterol interactions in the two leaflets of biological membranes.Effects of Charged Cholesterol Derivatives on Aβ40 Amyloid Formation.Amyloid-clearing proteins and their epigenetic regulation as a therapeutic target in Alzheimer's disease.The emerging role of bexarotene in the treatment of Alzheimer's disease: current evidence.New Insights into Epigenetic and Pharmacological Regulation of Amyloid-Degrading Enzymes.Do Cancer Drugs Counteract Neurodegeneration? Repurposing for Alzheimer's Disease.Amyloid beta: structure, biology and structure-based therapeutic development.Preclinical PET Neuroimaging of [11C]Bexarotene.Common molecular mechanism of amyloid pore formation by Alzheimer's β-amyloid peptide and α-synuclein.The Continuing Failure of Bexarotene in Alzheimer's Disease Mice.Binding of Bexarotene to the Amyloid Precursor Protein Transmembrane Domain in Liposomes Alters its α-Helical Conformation but Inhibits γ-Secretase Non-Selectively.
P2860
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P2860
Bexarotene blocks calcium-permeable ion channels formed by neurotoxic Alzheimer's β-amyloid peptides.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Bexarotene blocks calcium-perm ...... lzheimer's β-amyloid peptides.
@en
Bexarotene blocks calcium-perm ...... lzheimer's β-amyloid peptides.
@nl
type
label
Bexarotene blocks calcium-perm ...... lzheimer's β-amyloid peptides.
@en
Bexarotene blocks calcium-perm ...... lzheimer's β-amyloid peptides.
@nl
prefLabel
Bexarotene blocks calcium-perm ...... lzheimer's β-amyloid peptides.
@en
Bexarotene blocks calcium-perm ...... lzheimer's β-amyloid peptides.
@nl
P2093
P2860
P356
P1476
Bexarotene blocks calcium-perm ...... Alzheimer's β-amyloid peptides
@en
P2093
Henri Chahinian
Jacques Fantini
Jean-Denis Troadec
Kevin Sadelli
Nicolas Garmy
Nouara Yahi
P2860
P304
P356
10.1021/CN400183W
P577
2014-01-12T00:00:00Z