The histone demethylase KDM3A is a microRNA-22-regulated tumor promoter in Ewing Sarcoma.
about
What Do We Know about the Role of miRNAs in Pediatric Sarcoma?Sequencing Overview of Ewing Sarcoma: A Journey across Genomic, Epigenomic and Transcriptomic LandscapesVariable expression of PIK3R3 and PTEN in Ewing Sarcoma impacts oncogenic phenotypes.JMJD1A is a signal-sensing scaffold that regulates acute chromatin dynamics via SWI/SNF association for thermogenesisElevated JMJD1A is a novel predictor for prognosis and a potential therapeutic target for gastric cancer.MiR-193b, downregulated in Ewing Sarcoma, targets the ErbB4 oncogene to inhibit anchorage-independent growth.The KDM3A-KLF2-IRF4 axis maintains myeloma cell survival.Regulation of c-Myc expression by the histone demethylase JMJD1A is essential for prostate cancer cell growth and survival.Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription.Molecular mechanisms and clinical applications of miR-22 in regulating malignant progression in human cancer (Review).c-MYC drives histone demethylase PHF8 during neuroendocrine differentiation and in castration-resistant prostate cancer.Jumonji domain-containing protein 1A promotes cell growth and progression via transactivation of c-Myc expression and predicts a poor prognosis in cervical cancer.microRNA and Bone Cancer.KDM3A promotes inhibitory cytokines secretion by participating in TLR4 regulation of Foxp3 transcription in lung adenocarcinoma cells.KDM3A coordinates actin dynamics with intraflagellar transport to regulate cilia stability.MTA1-activated Epi-microRNA-22 regulates E-cadherin and prostate cancer invasiveness.JMJD1A promotes tumorigenesis and forms a feedback loop with EZH2/let-7c in NSCLC cells.Epigenetic and genetic changes in soft tissue sarcomas: a review.The histone demethylase KDM3A, and its downstream target MCAM, promote Ewing Sarcoma cell migration and metastasis.The histone demethylase Kdm3a is required for normal epithelial proliferation, ductal elongation and tumor growth in the mouse mammary gland.KDM3A inhibition attenuates high concentration insulin‑induced vascular smooth muscle cell injury by suppressing MAPK/NF‑κB pathways.The potential of KDM3A as a therapeutic target in Ewing Sarcoma and other cancers.KDM3A is not associated with metastasis and prognosis of breast cancer.The Jumonji-domain histone demethylase inhibitor JIB-04 deregulates oncogenic programs and increases DNA damage in Ewing Sarcoma, resulting in impaired cell proliferation and survival, and reduced tumor growth
P2860
Q26800124-AE818D21-2A6D-44BF-B2AE-15324CBA7C5EQ26801785-8D81B114-6907-4B9E-8403-0EA18387BDAAQ35545322-CE8245E2-5ECA-4C02-871B-8DFC501AD467Q35609053-5ED71DF8-3CBF-4907-971A-891CE32E9888Q36261640-AA1B8F65-D90F-4E3E-A104-3CEBD08F6044Q36380991-DD23D902-1880-4B78-ACD4-1D44BA045F69Q36506849-8FE3070C-87F0-481C-AFAC-54C2DEB2C8E4Q36590632-B76EFDDD-E7C0-4DF7-81A8-662796E680C0Q37157064-4FFCBB05-AB69-40AF-8AF3-9723584AB993Q37588086-EDE94566-323B-4C35-94AF-7433090C7853Q37688990-2B2A7A40-6635-4DD6-9088-4C1F4425E910Q37709105-85C7DC85-05CB-4048-991F-BFAFF18FE533Q38667026-FE5237C7-9CE2-441C-B01C-905F210CF9C9Q38703026-90473B79-928E-44D0-A13C-42E9B71D3265Q38714439-29CE68A2-6777-483F-869F-D7B125B978A0Q38715226-14797C12-A438-498A-B4A7-B9DCBFBBD5C5Q38788734-6703C46F-9C75-4B23-8711-21F883619D5DQ38964936-FB8BAA40-8AF1-4F90-8833-8910C89949E0Q41073699-0AB0C872-1CB9-4319-A5C2-AF32B77FF0BCQ47148565-F491DDD5-BAFC-48B2-9B3D-FCB1668436DDQ47246628-363816B3-00E2-4D9A-B9F5-B73C8FB60771Q49426157-AE701F6E-EA1A-4D87-9E77-A32D4103C7EBQ55253055-C8C900C5-94AA-4646-AD72-B7479E0A4C2BQ58764432-A42EE575-86B0-4FF3-B8CB-B7F9B52AAECB
P2860
The histone demethylase KDM3A is a microRNA-22-regulated tumor promoter in Ewing Sarcoma.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
The histone demethylase KDM3A is a microRNA-22-regulated tumor promoter in Ewing Sarcoma.
@en
The histone demethylase KDM3A is a microRNA-22-regulated tumor promoter in Ewing Sarcoma.
@nl
type
label
The histone demethylase KDM3A is a microRNA-22-regulated tumor promoter in Ewing Sarcoma.
@en
The histone demethylase KDM3A is a microRNA-22-regulated tumor promoter in Ewing Sarcoma.
@nl
prefLabel
The histone demethylase KDM3A is a microRNA-22-regulated tumor promoter in Ewing Sarcoma.
@en
The histone demethylase KDM3A is a microRNA-22-regulated tumor promoter in Ewing Sarcoma.
@nl
P2093
P2860
P356
P1433
P1476
The histone demethylase KDM3A is a microRNA-22-regulated tumor promoter in Ewing Sarcoma.
@en
P2093
P2860
P2888
P304
P356
10.1038/ONC.2013.541
P407
P577
2013-12-23T00:00:00Z