Design, synthesis, and evaluation of hydroxamic acid derivatives as promising agents for the management of Chagas disease.
about
WMJ-S-001, a novel aliphatic hydroxamate derivative, exhibits anti-angiogenic activities via Src-homology-2-domain-containing protein tyrosine phosphatase 1The effects of a novel aliphatic-chain hydroxamate derivative WMJ-S-001 in HCT116 colorectal cancer cell death.Recent advances in the discovery of zinc-binding motifs for the development of carbonic anhydrase inhibitors.Bacterial, fungal and protozoan carbonic anhydrases as drug targets.Inhibition of carbonic anhydrase from Trypanosoma cruzi for the management of Chagas disease: an underexplored therapeutic opportunity.WMJ-S-001, a novel aliphatic hydroxamate derivative, exhibits anti-inflammatory properties via MKP-1 in LPS-stimulated RAW264.7 macrophages.New light on bacterial carbonic anhydrases phylogeny based on the analysis of signal peptide sequences.Hydroxamic acid derivatives: a promising scaffold for rational compound optimization in Chagas disease.A failed tentative to design a super carbonic anhydrase having the biochemical properties of the most thermostable CA (SspCA) and the fastest (SazCA) enzymes.Protonography, a technique applicable for the analysis of η-carbonic anhydrase activity.Biochemical characterization of recombinant β-carbonic anhydrase (PgiCAb) identified in the genome of the oral pathogenic bacterium Porphyromonas gingivalis.A two-step tandem reaction to prepare hydroxamic acids directly from alcohols.Cloning, expression and purification of the complete domain of the η-carbonic anhydrase from Plasmodium falciparum.Nanoemulsions of sulfonamide carbonic anhydrase inhibitors strongly inhibit the growth of Trypanosoma cruzi.Carbonic anhydrases from Trypanosoma cruzi and Leishmania donovani chagasi are inhibited by benzoxaboroles.Protonography, a new technique for the analysis of carbonic anhydrase activity.Antileishmanial activity of sulphonamide nanoemulsions targeting the β-carbonic anhydrase from Leishmania species.Involvement of β-Carbonic Anhydrase Genes in Bacterial Genomic Islands and Their Horizontal Transfer to Protists
P2860
Q35238403-95E1205E-5DDA-4F89-ABB1-B0CC9E7B3C6FQ36221605-964F858C-6381-41CC-A865-548873F0796EQ38221060-BD8FFD64-4FE2-4C6F-833E-AEE40F497312Q38559435-FA04F0B8-6039-4EBE-891B-24AE96ED47EDQ38742510-B6273DAA-7409-478F-A433-EAAC3A4558DBQ38927398-DA73432F-95C5-44F2-97F4-6AC87891583AQ39647967-ADF604A3-BDAB-4A01-B9DA-FB8AAF70D1FDQ41022118-CBDA21F0-DB04-4C48-B66C-7CCE4F44FE96Q41434488-94FCEB01-AE6A-4F8A-B927-F657EB32103FQ41486816-ACE5418C-5B73-4573-A975-61B402F8C338Q46865783-38D36E92-CA55-4CCA-BCF3-5B1473498D3FQ47865463-B8FB8D36-4F4A-4DBB-A6B2-1A53730B4772Q47971588-9B7A3DFE-7C11-4953-9846-A3086E127E3FQ48205296-5657BE5C-4F2A-42C8-8869-CD1517DC803BQ49570857-F42766E6-C265-428E-B2E3-ADEEA2D5CAE5Q54285789-2C30CCCA-3FDE-42E1-9959-04DF52B5DB2DQ55611103-F7300ECD-4427-4FB1-BA61-771CBCA28F5FQ58459075-F14141D4-EE15-40DF-935C-DA0BACDD1FEC
P2860
Design, synthesis, and evaluation of hydroxamic acid derivatives as promising agents for the management of Chagas disease.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Design, synthesis, and evaluat ...... management of Chagas disease.
@en
Design, synthesis, and evaluat ...... management of Chagas disease.
@nl
type
label
Design, synthesis, and evaluat ...... management of Chagas disease.
@en
Design, synthesis, and evaluat ...... management of Chagas disease.
@nl
prefLabel
Design, synthesis, and evaluat ...... management of Chagas disease.
@en
Design, synthesis, and evaluat ...... management of Chagas disease.
@nl
P2093
P50
P356
P1476
Design, synthesis, and evaluat ...... e management of Chagas disease
@en
P2093
Alcino Palermo Aguiar
Claudiu T Supuran
Daniel Ferreira Feijó
Daniela Vullo
Giseli Capaci Rodrigues
Peiwen Pan
P304
P356
10.1021/JM400902Y
P407
P577
2013-12-13T00:00:00Z