about
Photoactivated DNA cleavage by compounds structurally related to the bithiazole moiety of bleomycin.A gadolinium-binding cyclodecapeptide with a large high-field relaxivity involving second-sphere water.In vivo optical imaging of integrin alphaV-beta3 in mice using multivalent or monovalent cRGD targeting vectors.Targeted delivery of a proapoptotic peptide to tumors in vivo.Application of click-click chemistry to the synthesis of new multivalent RGD conjugates.Clustering and internalization of integrin alphavbeta3 with a tetrameric RGD-synthetic peptide.Oxime ligation: a chemoselective click-type reaction for accessing multifunctional biomolecular constructs.67Cu-Radiolabeling of a multimeric RGD peptide for αVβ3 integrin-targeted radionuclide therapy: stability, therapeutic efficacy, and safety studies in mice.Systemic Delivery of Tumor-Targeted Bax-Derived Membrane-Active Peptides for the Treatment of Melanoma Tumors in a Humanized SCID Mouse Model.αVβ3 Integrin-Targeted Radionuclide Therapy with 64Cu-cyclam-RAFT-c(-RGDfK-)4.Targeted radionuclide therapy with RAFT-RGD radiolabelled with (90)Y or (177)Lu in a mouse model of αvβ3-expressing tumours.PET imaging and biodistribution analysis of the effects of succinylated gelatin combined with L-lysine on renal uptake and retention of ⁶⁴Cu-cyclam-RAFT-c(-RGDfK-)₄ in vivo.Micro-positron emission tomography/contrast-enhanced computed tomography imaging of orthotopic pancreatic tumor-bearing mice using the αvβ₃ integrin tracer ⁶⁴Cu-labeled cyclam-RAFT-c(-RGDfK-)₄.Integrin and matrix metalloprotease dual-targeting with an MMP substrate-RGD conjugate.Reduction of renal uptake of 111In-DOTA-labeled and A700-labeled RAFT-RGD during integrin αvβ3 targeting using single photon emission computed tomography and optical imaging.Noninvasive visualization and quantification of tumor αVβ3 integrin expression using a novel positron emission tomography probe, 64Cu-cyclam-RAFT-c(-RGDfK-)4.Cell adhesion through clustered ligand on fluid supported lipid bilayers.Highly efficient cell adhesion on beads functionalized with clustered peptide ligands.Drug development in oncology assisted by noninvasive optical imaging.In vivo imaging of tumour angiogenesis in mice with the alpha(v)beta (3) integrin-targeted tracer 99mTc-RAFT-RGD.Activatable fluorescent probes for tumour-targeting imaging in live mice.Multivalent RGD synthetic peptides as potent alphaVbeta3 integrin ligands.New multifunctional molecular conjugate vector for targeting, imaging, and therapy of tumors.From Peptide Aptamers to Inhibitors of FUR, Bacterial Transcriptional Regulator of Iron Homeostasis and Virulence.Binding of the chemokine CXCL12α to its natural extracellular matrix ligand heparan sulfate enables myoblast adhesion and facilitates cell motility.Inhibition of the ferric uptake regulator by peptides derived from anti-FUR peptide aptamers: coupled theoretical and experimental approaches.RGD-cyclam conjugate: synthesis and potential application for positron emission tomography.Highly efficient synthesis of peptide- and carbohydrate-oligonucleotide conjugates using chemoselective oxime and thiazolidine formation.Template assembled cyclopeptides as multimeric system for integrin targeting and endocytosis.One-pot approach to well-defined biomolecular assemblies by orthogonal chemoselective ligations.Chemical and biological evaluations of an (111)in-labeled RGD-peptide targeting integrin alpha(V) beta(3) in a preclinical tumor model.Synthesis and biological characterisation of targeted pro-apoptotic peptide.1-Ethoxyethylidene, a new group for the stepwise SPPS of aminooxyacetic acid containing peptides.Chemoselectively addressable template: a valuable tool for the engineering of molecular conjugates.Novel model peptide for Atx1-like metallochaperones."Polymultivalent" Polymer-Peptide Cluster Conjugates for an Enhanced Targeting of Cells Expressing αvβ3 Integrins.Luminescent Zinc Fingers: Zn-Responsive Neodymium Near-Infrared Emission in Water.Positron emission tomography of cerebral angiogenesis and TSPO expression in a mouse model of chronic hypoxia.Mercury Trithiolate Binding (HgS3) to a de Novo Designed Cyclic Decapeptide with Three Preoriented Cysteine Side Chains.Molecular imaging of vascular cell adhesion molecule-1 expression in experimental atherosclerotic plaques with radiolabelled B2702-p.
P50
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P50
description
hulumtues
@sq
researcher
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wetenschapper
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հետազոտող
@hy
name
Didier Boturyn
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Didier Boturyn
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Didier Boturyn
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Didier Boturyn
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Didier Boturyn
@sl
type
label
Didier Boturyn
@ast
Didier Boturyn
@en
Didier Boturyn
@es
Didier Boturyn
@nl
Didier Boturyn
@sl
prefLabel
Didier Boturyn
@ast
Didier Boturyn
@en
Didier Boturyn
@es
Didier Boturyn
@nl
Didier Boturyn
@sl
P1053
B-8214-2017
P106
P21
P31
P3829
P496
0000-0003-2530-0299