A novel inhibitor of the insulin/IGF signaling pathway protects from age-onset, neurodegeneration-linked proteotoxicity.
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The struggle by Caenorhabditis elegans to maintain proteostasis during aging and diseaseRemodeling of Proteostasis Upon Transition to Adulthood is Linked to Reproduction Onset.Alzheimer's disease-causing proline substitutions lead to presenilin 1 aggregation and malfunction.The Ames dwarf mutation attenuates Alzheimer's disease phenotype of APP/PS1 mice.Worming our way to novel drug discovery with the Caenorhabditis elegans proteostasis network, stress response and insulin-signaling pathways.Pharmacological classes that extend lifespan of Caenorhabditis elegansAkt2 ablation prolongs life span and improves myocardial contractile function with adaptive cardiac remodeling: role of Sirt1-mediated autophagy regulation.Protein Quality Control in Health and Disease.The Emerging Roles of Early Protein Folding Events in the Secretory Pathway in the Development of Neurodegenerative Maladies.Reduced insulin signaling maintains electrical transmission in a neural circuit in aging flies.Dietary-Induced Signals That Activate the Gonadal Longevity Pathway during Development Regulate a Proteostasis Switch in Caenorhabditis elegans AdulthoodHypoxia disrupts proteostasis in Caenorhabditis elegansYeast screening platform identifies FDA-approved drugs that reduce Aβ oligomerization.Liver protein profiles in insulin receptor-knockout mice reveal novel molecules involved in the diabetes pathophysiology.
P2860
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P2860
A novel inhibitor of the insulin/IGF signaling pathway protects from age-onset, neurodegeneration-linked proteotoxicity.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
A novel inhibitor of the insul ...... eration-linked proteotoxicity.
@en
A novel inhibitor of the insul ...... eration-linked proteotoxicity.
@nl
type
label
A novel inhibitor of the insul ...... eration-linked proteotoxicity.
@en
A novel inhibitor of the insul ...... eration-linked proteotoxicity.
@nl
prefLabel
A novel inhibitor of the insul ...... eration-linked proteotoxicity.
@en
A novel inhibitor of the insul ...... eration-linked proteotoxicity.
@nl
P2093
P2860
P356
P1433
P1476
A novel inhibitor of the insul ...... eration-linked proteotoxicity.
@en
P2093
Filipa Carvalhal Marques
Hadas Reuveni
Lorna Moll
Tayir El-Ami
Yuli Volovik
P2860
P304
P356
10.1111/ACEL.12171
P50
P577
2013-11-22T00:00:00Z