Multitarget drug discovery projects in CNS diseases: quantitative systems pharmacology as a possible path forward.

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Predictive Big Data Analytics: A Study of Parkinson's Disease Using Large, Complex, Heterogeneous, Incongruent, Multi-Source and Incomplete Observations.Phosphodiesterase 10 inhibitors in clinical development for CNS disorders.

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P2860

Multitarget drug discovery projects in CNS diseases: quantitative systems pharmacology as a possible path forward.

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2014 nî lūn-bûn

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Multitarget drug discovery pro ...... gy as a possible path forward.

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Multitarget drug discovery pro ...... gy as a possible path forward.

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Multitarget drug discovery pro ...... gy as a possible path forward.

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Multitarget drug discovery pro ...... gy as a possible path forward.

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Multitarget drug discovery pro ...... gy as a possible path forward.

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Multitarget drug discovery pro ...... gy as a possible path forward.

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Hugo Geerts

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Ludo Kennis

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P2860

A long-term, phase 2, multicenter, randomized, open-label, comparative safety study of pomaglumetad methionil (LY2140023 monohydrate) versus atypical antipsychotic standard of care in patients with schizophrenia

Efficacy and safety of individual second-generation vs. first-generation antipsychotics in first-episode psychosis: a systematic review and meta-analysis

Meta-analysis of the efficacy of adjunctive NMDA receptor modulators in chronic schizophrenia

A single 20 mg dose of dihydrexidine (DAR-0100), a full dopamine D1 agonist, is safe and tolerated in patients with schizophrenia

Tumor and host factors that may limit efficacy of chemotherapy in non-small cell and small cell lung cancer

Phosphodiesterase 10A inhibitor MP-10 effects in primates: comparison with risperidone and mechanistic implications

Blinded prospective evaluation of computer-based mechanistic schizophrenia disease model for predicting drug response

How were new medicines discovered?

The presynaptic component of the serotonergic system is required for clozapine's efficacy.

Efficacy and safety of noradrenalin reuptake inhibitor augmentation therapy for schizophrenia: a meta-analysis of double-blind randomized placebo-controlled trials.

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1757-1769

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scholarly article

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10.4155/FMC.14.97

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Farmakologi

Multitarget drug discovery projects in CNS diseases: quantitative systems pharmacology as a possible path forward.

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P2860

P2860

Multitarget drug discovery projects in CNS diseases: quantitative systems pharmacology as a possible path forward.

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