Targeted therapy against chemoresistant colorectal cancers: Inhibition of p38α modulates the effect of cisplatin in vitro and in vivo through the tumor suppressor FoxO3A.

Targeted therapy against chemoresistant colorectal cancers: Inhibition of p38α modulates the effect of cisplatin in vitro and in vivo through the tumor suppressor FoxO3A.

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http://www.wikidata.org/entity/Q39064624
p38MAPK and Chemotherapy: We Always Need to Hear Both Sides of the StorymiR-625-3p regulates oxaliplatin resistance by targeting MAP2K6-p38 signalling in human colorectal adenocarcinoma cellsp38α MAPK pathway: a key factor in colorectal cancer therapy and chemoresistance.Baicalein increases the expression and reciprocal interplay of RUNX3 and FOXO3a through crosstalk of AMPKα and MEK/ERK1/2 signaling pathways in human non-small cell lung cancer cells.Pharmacological inhibition of p38 MAPK reduces tumor growth in patient-derived xenografts from colon tumorsButein sensitizes HeLa cells to cisplatin through the AKT and ERK/p38 MAPK pathways by targeting FoxO3a.MicroRNA-21 promotes proliferation, migration, and invasion of colorectal cancer, and tumor growth associated with down-regulation of sec23a expression.Chinese Herbal Medicine Fuzheng Kang-Ai Decoction Inhibited Lung Cancer Cell Growth through AMPKα-Mediated Induction and Interplay of IGFBP1 and FOXO3a.Inter-regulation of IGFBP1 and FOXO3a unveils novel mechanism in ursolic acid-inhibited growth of hepatocellular carcinoma cells.FOXO3a and the MAPK p38 are activated by cetuximab to induce cell death and inhibit cell proliferation and their expression predicts cetuximab efficacy in colorectal cancer.An oncogenic role of miR-592 in tumorigenesis of human colorectal cancer by targeting Forkhead Box O3A (FoxO3A).Clinicopathological significance of p38β, p38γ, and p38δ and its biological roles in esophageal squamous cell carcinoma.Proline isomerisation as a novel regulatory mechanism for p38MAPK activation and functions.Intricatinol synergistically enhances the anticancerous activity of cisplatin in human A549 cells via p38 MAPK/p53 signalling.Uncoupling FoxO3A mitochondrial and nuclear functions in cancer cells undergoing metabolic stress and chemotherapy.The longevity SNP rs2802292 uncovered: HSF1 activates stress-dependent expression of FOXO3 through an intronic enhancer.
P2860

Targeted therapy against chemoresistant colorectal cancers: Inhibition of p38α modulates the effect of cisplatin in vitro and in vivo through the tumor suppressor FoxO3A.

Item
http://www.wikidata.org/entity/Q39064624
description
2013 nî lūn-bûn
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
@zh-tw
2013年论文
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2013年论文
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2013年论文
@zh-cn
name
Targeted therapy against chemo ...... h the tumor suppressor FoxO3A.
@en
Targeted therapy against chemo ...... h the tumor suppressor FoxO3A.
@nl
type
label
Targeted therapy against chemo ...... h the tumor suppressor FoxO3A.
@en
Targeted therapy against chemo ...... h the tumor suppressor FoxO3A.
@nl
prefLabel
Targeted therapy against chemo ...... h the tumor suppressor FoxO3A.
@en
Targeted therapy against chemo ...... h the tumor suppressor FoxO3A.
@nl
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P1476
P2093
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Targeted therapy against chemo ...... gh the tumor suppressor FoxO3A
@en
P2093
P304
P31
P356
10.1016/J.CANLET.2013.10.035
P407
P433
P478
P50
P577
P5875
P698