Translational Modeling and Simulation in Supporting Early-Phase Clinical Development of New Drug: A Learn-Research-Confirm Process.

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Comparison of Power, Prognosis, and Extrapolation Properties of Four Population Pharmacodynamic Models of HbA1c for Type 2 Diabetes.

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Translational Modeling and Simulation in Supporting Early-Phase Clinical Development of New Drug: A Learn-Research-Confirm Process.

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Translational Modeling and Sim ...... earn-Research-Confirm Process.

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Translational Modeling and Sim ...... earn-Research-Confirm Process.

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Translational Modeling and Sim ...... earn-Research-Confirm Process.

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Translational Modeling and Sim ...... earn-Research-Confirm Process.

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Dalong Zhu

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Dawei Xiao

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Dongyang Liu

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Hongwei Fan

http://www.w3.org/2001/XMLSchema#string

Ji Jiang

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John Choi

http://www.w3.org/2001/XMLSchema#string

Li Chen

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Pei Hu

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Xuening Li

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Yanhua Ding

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P2860

An integrated glucose-insulin model to describe oral glucose tolerance test data in type 2 diabetics.

PsN-Toolkit--a collection of computer intensive statistical methods for non-linear mixed effect modeling using NONMEM.

Glucose turnover and disposal in maturity-onset diabetes.

Quantitation of basal endogenous glucose production in Type II diabetes: importance of the volume of distribution.

Assessing the potential of glucokinase activators in diabetes therapy.

A semi-mechanistic model for the effects of a novel glucagon receptor antagonist on glucagon and the interaction between glucose, glucagon, and insulin applied to adaptive phase II design.

Glucokinase activators for diabetes therapy: May 2010 status report

Intestinal permeability and its relevance for absorption and elimination.

Combining 'Bottom-Up' and 'Top-Down' Methods to Assess Ethnic Difference in Clearance: Bitopertin as an Example.

Mechanism-based pharmacokinetic-pharmacodynamic (PK-PD) modeling in translational drug research.

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s40262-016-0484-2

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925-939

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scholarly article

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10.1007/S40262-016-0484-2

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Translational Modeling and Simulation in Supporting Early-Phase Clinical Development of New Drug: A Learn-Research-Confirm Process.

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P2860

Translational Modeling and Simulation in Supporting Early-Phase Clinical Development of New Drug: A Learn-Research-Confirm Process.

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