Pathogen signatures activate a ubiquitination pathway that modulates the function of the metabolic checkpoint kinase mTOR.
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Post-transcriptional Regulation of Immunological Responses through RiboclusteringModulation of the host innate immune and inflammatory response by translocated bacterial proteinsEffects of Interferons and Viruses on MetabolismCurcumin Suppresses Proliferation and Migration of MDA-MB-231 Breast Cancer Cells through Autophagy-Dependent Akt DegradationNeutrophils and Ly6Chi monocytes collaborate in generating an optimal cytokine response that protects against pulmonary Legionella pneumophila infection.Global analysis of gene expression reveals mRNA superinduction is required for the inducible immune response to a bacterial pathogen.Regnase-1, a rapid response ribonuclease regulating inflammation and stress responses.The frustrated host response to Legionella pneumophila is bypassed by MyD88-dependent translation of pro-inflammatory cytokines.Rab8a interacts directly with PI3Kγ to modulate TLR4-driven PI3K and mTOR signalling.The transcriptome of Legionella pneumophila-infected human monocyte-derived macrophages.IL-1R signaling enables bystander cells to overcome bacterial blockade of host protein synthesis.Legionella suppresses the host unfolded protein response via multiple mechanisms.Tribbles ortholog NIPI-3 and bZIP transcription factor CEBP-1 regulate a Caenorhabditis elegans intestinal immune surveillance pathway.MTOR-Driven Metabolic Reprogramming Regulates Legionella pneumophila Intracellular Niche Homeostasis.Inhibition of host cell translation elongation by Legionella pneumophila blocks the host cell unfolded protein responseOpposing regulation of the late phase TNF response by mTORC1-IL-10 signaling and hypoxia in human macrophagesmTORC1-Activated Monocytes Increase Tregs and Inhibit the Immune Response to Bacterial Infections.Outrunning the Red Queen: bystander activation as a means of outpacing innate immune subversion by intracellular pathogens.The emerging role of mTOR signalling in antibacterial immunity.Post-transcriptional coordination of immunological responses by RNA-binding proteins.Autophagy response: manipulating the mTOR-controlled machinery by amino acids and pathogens.Creating a customized intracellular niche: subversion of host cell signaling by Legionella type IV secretion system effectors.Regulation of innate immune cell function by mTOR.Host Cell S Phase Restricts Legionella pneumophila Intracellular Replication by Destabilizing the Membrane-Bound Replication Compartment.AMPK and mTOR: sensors and regulators of immunometabolic changes during Salmonella infection in the chicken.mTOR-Mediated Regulation of Dendritic Cell Differentiation and Function.Complete and ubiquitinated proteome of the Legionella-containing vacuole within human macrophages.mTORC1 and mTORC2 as regulators of cell metabolism in immunity.Vibrio vulnificus induces mTOR activation and inflammatory responses in macrophages.Small GTPase Rab8a-recruited Phosphatidylinositol 3-Kinase γ Regulates Signaling and Cytokine Outputs from Endosomal Toll-like Receptors.Eliminating Legionella by inhibiting BCL-XL to induce macrophage apoptosis.Rapamycin regulates macrophage activation by inhibiting NLRP3 inflammasome-p38 MAPK-NFκB pathways in autophagy- and p62-dependent manners.Interferon-γ regulates cellular metabolism and mRNA translation to potentiate macrophage activation.Rtp801 suppression of epithelial mTORC1 augments endotoxin-induced lung inflammation.Loss of translation: a stealth weapon against pathogens?Positive and Negative Regulation of the Master Metabolic Regulator mTORC1 by Two Families of Legionella pneumophila Effectors.How to rewire the host cell: A home improvement guide for intracellular bacteria.Multiple Legionella pneumophila effector virulence phenotypes revealed through high-throughput analysis of targeted mutant libraries.The Toolbox for Uncovering the Functions of Legionella Dot/Icm Type IVb Secretion System Effectors: Current State and Future Directions.
P2860
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P2860
Pathogen signatures activate a ubiquitination pathway that modulates the function of the metabolic checkpoint kinase mTOR.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Pathogen signatures activate a ...... abolic checkpoint kinase mTOR.
@en
Pathogen signatures activate a ...... abolic checkpoint kinase mTOR.
@nl
type
label
Pathogen signatures activate a ...... abolic checkpoint kinase mTOR.
@en
Pathogen signatures activate a ...... abolic checkpoint kinase mTOR.
@nl
prefLabel
Pathogen signatures activate a ...... abolic checkpoint kinase mTOR.
@en
Pathogen signatures activate a ...... abolic checkpoint kinase mTOR.
@nl
P2860
P356
P1433
P1476
Pathogen signatures activate a ...... abolic checkpoint kinase mTOR.
@en
P2860
P2888
P304
P356
10.1038/NI.2740
P407
P577
2013-10-13T00:00:00Z
P5875
P6179
1014648535