Sulfate metabolites provide an intracellular pool for resveratrol generation and induce autophagy with senescence. - Wikidata - awgldk - TriplyDB

Sulfate metabolites provide an intracellular pool for resveratrol generation and induce autophagy with senescence.

Sulfate metabolites provide an intracellular pool for resveratrol generation and induce autophagy with senescence.

http://www.wikidata.org/entity/Q39088576

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Role of Natural Stilbenes in the Prevention of Cancer New concepts and challenges in the clinical translation of cancer preventive therapies: the role of pharmacodynamic biomarkers Resveratrol and cancer: Challenges for clinical translation Bridging Type 2 Diabetes and Alzheimer's Disease: Assembling the Puzzle Pieces in the Quest for the Molecules With Therapeutic and Preventive Potential Conformational changes and translocation of tissue-transglutaminase to the plasma membranes: role in cancer cell migration.Improving In Vivo Efficacy of Bioactive Molecules: An Overview of Potentially Antitumor Phytochemicals and Currently Available Lipid-Based Delivery Systems.Effects of resveratrol on drug- and carcinogen-metabolizing enzymes, implications for cancer prevention.Resveratrol inhibits estrogen-induced breast carcinogenesis through induction of NRF2-mediated protective pathways.Calorie restriction combined with resveratrol induces autophagy and protects 26-month-old rat hearts from doxorubicin-induced toxicity Autophagy and oxidative stress in cardiovascular diseases.Development of a lozenge for oral transmucosal delivery of trans-resveratrol in humans: proof of concept Impact of trans-resveratrol-sulfates and -glucuronides on endothelial nitric oxide synthase activity, nitric oxide release and intracellular reactive oxygen species.The ellagic acid-derived gut microbiota metabolite, urolithin A, potentiates the anticancer effects of 5-fluorouracil chemotherapy on human colon cancer cells.Resveratrol Antagonizes Antimicrobial Lethality and Stimulates Recovery of Bacterial Mutants.A simple LC-MS/MS method facilitated by salting-out assisted liquid-liquid extraction to simultaneously determine trans-resveratrol and its glucuronide and sulfate conjugates in rat plasma and its application to pharmacokinetic assay.Glyceollin Effects on MRP2 and BCRP in Caco-2 Cells, and Implications for Metabolic and Transport Interactions.Cancer chemoprevention: Evidence of a nonlinear dose response for the protective effects of resveratrol in humans and mice Pterostilbene Decreases the Antioxidant Defenses of Aggressive Cancer Cells In Vivo: A Physiological Glucocorticoids- and Nrf2-Dependent Mechanism The role of microRNAs in the regulation of cancer stem cells.Cocoa polyphenols and inflammatory markers of cardiovascular disease.The multiple mechanisms of cell death triggered by resveratrol in lymphoma and leukemia.Enhancing the delivery of resveratrol in humans: if low bioavailability is the problem, what is the solution?Quercetin and related polyphenols: new insights and implications for their bioactivity and bioavailability.Direct molecular targets of resveratrol: identifying key interactions to unlock complex mechanisms.Therapeutic potential of resveratrol in heart failure.Resveratrol and its major sulfated conjugates are substrates of organic anion transporting polypeptides (OATPs): impact on growth of ZR-75-1 breast cancer cells.Targeting extracellular matrix remodeling in disease: Could resveratrol be a potential candidate?Resveratrol directly targets DDX5 resulting in suppression of the mTORC1 pathway in prostate cancer.Placebo-controlled, randomised clinical trial: high-dose resveratrol treatment for non-alcoholic fatty liver disease.Differential sensitivities of bladder cancer cell lines to resveratol are unrelated to its metabolic profile.Amino Acid Carbamates As Prodrugs Of Resveratrol.Resveratrol improves hepatic steatosis by inducing autophagy through the cAMP signaling pathway.Resveratrol activates duodenal Sirt1 to reverse insulin resistance in rats through a neuronal network.Resveratrol prevents pathological but not physiological cardiac hypertrophy.Resveratrol and inflammatory bowel disease: the evidence so far.In Vitro Glucuronidation and Sulfation of ε-Viniferin, a Resveratrol Dimer, in Humans and Rats.Pharmacokinetics and tissue distribution of pterostilbene in the rat.Whole-cell-dependent biosynthesis of sulfo-conjugate using human sulfotransferase expressing budding yeast.Role of sulfotransferases in resveratrol metabolism in human adipocytes.Effect of resveratrol on experimental non-alcoholic fatty liver disease depends on severity of pathology and timing of treatment.

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P2860

Sulfate metabolites provide an intracellular pool for resveratrol generation and induce autophagy with senescence.

http://www.wikidata.org/entity/Q39088576

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name

Sulfate metabolites provide an ...... uce autophagy with senescence.

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Sulfate metabolites provide an ...... uce autophagy with senescence.

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Sulfate metabolites provide an ...... uce autophagy with senescence.

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Sulfate metabolites provide an ...... uce autophagy with senescence.

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Sulfate metabolites provide an ...... uce autophagy with senescence.

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Sulfate metabolites provide an ...... uce autophagy with senescence.

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SCITRANSLMED.3005870

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Science Translational Medicine

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Sulfate metabolites provide an ...... uce autophagy with senescence.

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P2093

Andreas J Gescher

http://www.w3.org/2001/XMLSchema#string

Ankur Karmokar

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Catherine Andreadi

http://www.w3.org/2001/XMLSchema#string

Dean E Brenner

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Emma Horner-Glister

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Karen Brown

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Ketan R Patel

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Rajinder Singh

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Robert G Britton

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Stewart Sale

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P2860

What is new for an old molecule? Systematic review and recommendations on the use of resveratrol

Autophagy mediates the mitotic senescence transition

Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy

Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span

OATPs, OATs and OCTs: the organic anion and cation transporters of the SLCO and SLC22A gene superfamilies

Resveratrol improves health and survival of mice on a high-calorie diet

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

Resveratrol inhibits pancreatic cancer stem cell characteristics in human and KrasG12D transgenic mice by inhibiting pluripotency maintaining factors and epithelial-mesenchymal transition

Therapeutic potential of resveratrol: the in vivo evidence

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10.1126/SCITRANSLMED.3005870

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205

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5

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2013-10-01T00:00:00Z

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24089405

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resveratrol-3-O-sulfate