Discovery of indeno[1, 2 - c] quinoline derivatives as dual topoisomerases I/II inhibitors: part 3.

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Synthesis and antiproliferative evaluation of 9-methoxy-6-(piperazin-1-yl)-11H-indeno[1,2-c]quinoline-11-one derivatives. Part 4

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Discovery of indeno[1, 2 - c] quinoline derivatives as dual topoisomerases I/II inhibitors: part 3.

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2013 nî lūn-bûn

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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Discovery of indeno[1, 2 - c] ...... rases I/II inhibitors: part 3.

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Discovery of indeno[1, 2 - c] ...... rases I/II inhibitors: part 3.

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Discovery of indeno[1, 2 - c] ...... rases I/II inhibitors: part 3.

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Discovery of indeno[1, 2 - c] ...... rases I/II inhibitors: part 3.

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Discovery of indeno[1, 2 - c] ...... rases I/II inhibitors: part 3.

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Discovery of indeno[1, 2 - c] ...... rases I/II inhibitors: part 3.

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P1476

Discovery of indeno[1, 2 - c] ...... rases I/II inhibitors: part 3.

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P2093

Cherng-Chyi Tzeng

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Chia-Ning Yang

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Chiao-Li Yang

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Chien-Yu Chen

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Chih-Hua Tseng

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Hui-Ling Chen

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Pei-Jung Lu

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Yeh-Long Chen

http://www.w3.org/2001/XMLSchema#string

Yu-Peng Liu

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A new mechanism of 6-((2-(dimethylamino)ethyl)amino)-3-hydroxy-7H-indeno(2,1-c)quinolin-7-one dihydrochloride (TAS-103) action discovered by target screening with drug-immobilized affinity beads

Synthesis and biological evaluation of 14-(aminoalkyl-aminomethyl)aromathecins as topoisomerase I inhibitors: Investigating the hypothesis of shared structure–activity relationships

Mitotic arrest induced by a novel family of DNA topoisomerase II inhibitors.

Structure-based design, synthesis, and biological studies of new anticancer norindenoisoquinoline topoisomerase I inhibitors

Self-association and unique DNA binding properties of the anti-cancer agent TAS-103, a dual inhibitor of topoisomerases I and II.

Inhibition of PC12 cell redox activity is a specific, early indicator of the mechanism of beta-amyloid-mediated cell death

12-Substituted 2,3-dimethoxy-8,9-methylenedioxybenzo[i]phenanthridines as novel topoisomerase I-targeting antitumor agents.

Novel topoisomerase I-targeting antitumor agents synthesized from the N,N,N-trimethylammonium derivative of ARC-111, 5H-2,3-dimethoxy-8,9-methylenedioxy-5-[(2-N,N,N-trimethylammonium)ethyl]dibenzo[c,h][1,6]naphthyridin-6-one iodide.

Luteolin, an emerging anti-cancer flavonoid, poisons eukaryotic DNA topoisomerase I.

DNA topoisomerase II: a primer on the enzyme and its unique role as a multidrug target in cancer chemotherapy.

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s11030-013-9475-5

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scholarly article

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10.1007/S11030-013-9475-5

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Discovery of indeno[1, 2 - c] quinoline derivatives as dual topoisomerases I/II inhibitors: part 3.

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P2860

P2860

Discovery of indeno[1, 2 - c] quinoline derivatives as dual topoisomerases I/II inhibitors: part 3.

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