Inhibition of the mitochondrial pyrimidine biosynthesis enzyme dihydroorotate dehydrogenase by doxorubicin and brequinar sensitizes cancer cells to TRAIL-induced apoptosis.
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Trailing TRAIL Resistance: Novel Targets for TRAIL Sensitization in Cancer CellsMitochondria as biosynthetic factories for cancer proliferation.Tracer-Based Metabolic NMR-Based Flux Analysis in a Leukaemia Cell Line.Fluorescence assay of dihydroorotate dehydrogenase that may become a cancer biomarkerDihydroorotate dehydrogenase Inhibitors Target c-Myc and Arrest Melanoma, Myeloma and Lymphoma cells at S-phaseMetabolomic Evidence for a Field Effect in Histologically Normal and Metaplastic Tissues in Patients with Esophageal Adenocarcinoma.High-throughput cell-based compound screen identifies pinosylvin methyl ether and tanshinone IIA as inhibitors of castration-resistant prostate cancer.Inactivation/deficiency of DHODH induces cell cycle arrest and programed cell death in melanoma.Design, Synthesis, and Characterization of Brequinar Conjugates as Probes to Study DHODH Inhibition.
P2860
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P2860
Inhibition of the mitochondrial pyrimidine biosynthesis enzyme dihydroorotate dehydrogenase by doxorubicin and brequinar sensitizes cancer cells to TRAIL-induced apoptosis.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Inhibition of the mitochondria ...... ls to TRAIL-induced apoptosis.
@en
Inhibition of the mitochondria ...... ls to TRAIL-induced apoptosis.
@nl
type
label
Inhibition of the mitochondria ...... ls to TRAIL-induced apoptosis.
@en
Inhibition of the mitochondria ...... ls to TRAIL-induced apoptosis.
@nl
prefLabel
Inhibition of the mitochondria ...... ls to TRAIL-induced apoptosis.
@en
Inhibition of the mitochondria ...... ls to TRAIL-induced apoptosis.
@nl
P2093
P2860
P50
P356
P1433
P1476
Inhibition of the mitochondria ...... ls to TRAIL-induced apoptosis.
@en
P2093
P2860
P2888
P304
P356
10.1038/ONC.2013.313
P407
P577
2013-09-09T00:00:00Z