The H3K27 demethylase UTX-1 regulates C. elegans lifespan in a germline-independent, insulin-dependent manner.
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Depletion of nuclear histone H2A variants is associated with chronic DNA damage signaling upon drug-evoked senescence of human somatic cellsThe histone chaperone Spt6 coordinates histone H3K27 demethylation and myogenesisEpigenetics and agingEpigenetic perturbations in aging stem cellsEpigenetic Control of Haematopoietic Stem Cell Aging and Its Clinical ImplicationsHistone methylation makes its mark on longevityInduction of cytoprotective pathways is central to the extension of lifespan conferred by multiple longevity pathwaysThe C. elegans H3K27 demethylase UTX-1 is essential for normal development, independent of its enzymatic activityHistone methylation: a dynamic mark in health, disease and inheritanceIncreasing Notch signaling antagonizes PRC2-mediated silencing to promote reprograming of germ cells into neuronsDistribution and prediction of catalytic domains in 2-oxoglutarate dependent dioxygenases.Lysosome-mediated processing of chromatin in senescence.Age-associated chromatin relaxation is enhanced in Huntington's disease mice.H3K4 demethylase activities repress proliferative and postmitotic aging.Epigenetics of aging and aging-related disease.Transcriptional regulation of Caenorhabditis elegans FOXO/DAF-16 modulates lifespan.A complex regulatory network coordinating cell cycles during C. elegans development is revealed by a genome-wide RNAi screen.The H3K27me3 demethylase UTX in normal development and disease.Chromatin modifications as determinants of muscle stem cell quiescence and chronological aging.Males shorten the life span of C. elegans hermaphrodites via secreted compounds2-Oxoglutarate-dependent dioxygenases are sensors of energy metabolism, oxygen availability, and iron homeostasis: potential role in the regulation of aging process.Histone methylation and aging: lessons learned from model systems.Use of epigenetic drugs in disease: an overview.The GATA transcription factor/MTA-1 homolog egr-1 promotes longevity and stress resistance in Caenorhabditis elegans.Trimethylation of Lys36 on H3 restricts gene expression change during aging and impacts life span.From inflammaging to healthy aging by dietary lifestyle choices: is epigenetics the key to personalized nutrition?Two SET domain containing genes link epigenetic changes and aging in Caenorhabditis elegansRepression of the Heat Shock Response Is a Programmed Event at the Onset of Reproduction.Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans.Histone modifications change with age, dietary restriction and rapamycin treatment in mouse brainAging and reprogramming: a two-way street.Epigenetic regulation of ageing: linking environmental inputs to genomic stability.Mitochondrial metabolites extend lifespan.Epigenetic memory of longevity in Caenorhabditis elegansCatalytic-independent roles of UTX-1 in C. elegans development.The Aging EpigenomeUltraviolet-A triggers photoaging in model nematode Caenorhabditis elegans in a DAF-16 dependent pathway.Chromatin structure and transposable elements in organismal aging.Aging and epigenetic drift: a vicious cycle.Loss of Nat4 and its associated histone H4 N-terminal acetylation mediates calorie restriction-induced longevity.
P2860
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P2860
The H3K27 demethylase UTX-1 regulates C. elegans lifespan in a germline-independent, insulin-dependent manner.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
The H3K27 demethylase UTX-1 re ...... ent, insulin-dependent manner.
@en
The H3K27 demethylase UTX-1 re ...... ent, insulin-dependent manner.
@nl
type
label
The H3K27 demethylase UTX-1 re ...... ent, insulin-dependent manner.
@en
The H3K27 demethylase UTX-1 re ...... ent, insulin-dependent manner.
@nl
prefLabel
The H3K27 demethylase UTX-1 re ...... ent, insulin-dependent manner.
@en
The H3K27 demethylase UTX-1 re ...... ent, insulin-dependent manner.
@nl
P2093
P2860
P1433
P1476
The H3K27 demethylase UTX-1 re ...... ent, insulin-dependent manner.
@en
P2093
Anna G Hauswirth
Anne Brunet
Travis J Maures
P2860
P304
P356
10.1111/J.1474-9726.2011.00738.X
P50
P577
2011-09-16T00:00:00Z