TRAF4 promotes TGF-β receptor signaling and drives breast cancer metastasis. - Wikidata - awgldk - TriplyDB

TRAF4 promotes TGF-β receptor signaling and drives breast cancer metastasis.

TRAF4 promotes TGF-β receptor signaling and drives breast cancer metastasis.

http://www.wikidata.org/entity/Q39105929

about

TRAF4 Is a Novel Phosphoinositide-Binding Protein Modulating Tight Junctions and Favoring Cell Migration Targeting tumor-associated macrophages to combat pancreatic cancer USP15 regulates SMURF2 kinetics through C-lobe mediated deubiquitination.Reconstruction of temporal activity of microRNAs from gene expression data in breast cancer cell line.The PIAS3-Smurf2 sumoylation pathway suppresses breast cancer organoid invasiveness.Regulation of Ubiquitin Enzymes in the TGF-β Pathway.FAF1 phosphorylation by AKT accumulates TGF-β type II receptor and drives breast cancer metastasis.The regulation of TGF-β/SMAD signaling by protein deubiquitination.Ubiquitin-conjugating enzyme Ubc13 controls breast cancer metastasis through a TAK1-p38 MAP kinase cascade.The phosphoinositide-binding protein TRAF4 modulates tight junction stability and migration of cancer cells.Transforming growth factor-β signalling controls human breast cancer metastasis in a zebrafish xenograft model.Targeting of TGF-β-activated protein kinase 1 inhibits chemokine (C-C motif) receptor 7 expression, tumor growth and metastasis in breast cancer.TRAF4-SMURF2-mediated DAZAP2 degradation is critical for IL-25 signaling and allergic airway inflammation.P21 activated kinase-1 mediates transforming growth factor β1-induced prostate cancer cell epithelial to mesenchymal transition.Genetic depletion and pharmacological targeting of αv integrin in breast cancer cells impairs metastasis in zebrafish and mouse xenograft models.Ubiquitin-specific proteases as therapeutic targets for the treatment of breast cancer TRAF4 promotes the growth and invasion of colon cancer through the Wnt/β-catenin pathway.Cytoplasmic TRAF4 contributes to the activation of p70s6k signaling pathway in breast cancer.Dynamical Regulation Analysis Identifies Molecular Mechanisms of Fuzheng-Huayu Formula against Hepatitis B-Caused Liver Cirrhosis.Bufalin inhibits TGF-β-induced epithelial-to-mesenchymal transition and migration in human lung cancer A549 cells by downregulating TGF-β receptors.Inhibition of BMP and of TGFβ receptors downregulates expression of XIAP and TAK1 leading to lung cancer cell death.Signaling pathway cooperation in TGF-β-induced epithelial-mesenchymal transition.DCAF4L2 promotes colorectal cancer invasion and metastasis via mediating degradation of NFκb negative regulator PPM1B Transcriptional Profiling and miRNA-Target Network Analysis Identify Potential Biomarkers for Efficacy Evaluation of Fuzheng-Huayu Formula-Treated Hepatitis B Caused Liver Cirrhosis.TRAF4 mediates activation of TGF-β signaling and is a biomarker for oncogenesis in breast cancer.Emerging roles of Lys63-linked polyubiquitylation in immune responses.The rationale for targeting TGF-β in chronic liver diseases.Molecular insights into tumour metastasis: tracing the dominant events.TRAF4 enhances oral squamous cell carcinoma cell growth, invasion and migration by Wnt-β-catenin signaling pathway.Epigenetic regulation of Smad2 and Smad3 by profilin-2 promotes lung cancer growth and metastasis.Urocortin attenuates TGFβ1-induced Snail1 and slug expressions: inhibitory role of Smad7 in Smad2/3 signaling in breast cancer cells.TGF-β Signaling from Receptors to Smads.Signaling Receptors for TGF-β Family Members.TRAF6 promotes TGFβ-induced invasion and cell-cycle regulation via Lys63-linked polyubiquitination of Lys178 in TGFβ type I receptor.Time-resolved dissection of early phosphoproteome and ensuing proteome changes in response to TGF-β.TRAF4 participates in Wnt/β-catenin signaling in breast cancer by upregulating β-catenin and mediating its translocation to the nucleus.Signaling Cross Talk between TGF-β/Smad and Other Signaling Pathways.The importance of regulatory ubiquitination in cancer and metastasis.Generation, expansion and functional analysis of endothelial cells and pericytes derived from human pluripotent stem cells.FocalScan: Scanning for altered genes in cancer based on coordinated DNA and RNA change

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TRAF4 promotes TGF-β receptor signaling and drives breast cancer metastasis.

http://www.wikidata.org/entity/Q39105929

description

2013 nî lūn-bûn

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2013年の論文

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name

TRAF4 promotes TGF-β receptor signaling and drives breast cancer metastasis.

@en

TRAF4 promotes TGF-β receptor signaling and drives breast cancer metastasis.

@nl

type

label

TRAF4 promotes TGF-β receptor signaling and drives breast cancer metastasis.

@en

TRAF4 promotes TGF-β receptor signaling and drives breast cancer metastasis.

@nl

prefLabel

TRAF4 promotes TGF-β receptor signaling and drives breast cancer metastasis.

@en

TRAF4 promotes TGF-β receptor signaling and drives breast cancer metastasis.

@nl

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J.MOLCEL.2013.07.014

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TRAF4 promotes TGF-β receptor signaling and drives breast cancer metastasis.

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Adrien Rousseau

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Amaya García de Vinuesa

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Andreas Bauer

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Chris X Lu

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Craig Mickanin

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Esther M de Kruijf

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Fangfang Zhou

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Kelly-Ann Sheppard

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Li Hui

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Long Zhang

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scholarly article

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10.1016/J.MOLCEL.2013.07.014

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23973329

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