Human embryonic stem cell derived hepatocyte-like cells as a tool for in vitro hazard assessment of chemical carcinogenicity
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Stem cell-derived liver cells for drug testing and disease modelingStem cell-derived hepatocytes as a predictive model for drug-induced liver injury: are we there yet?Analyzing and interpreting genome data at the network level with ConsensusPathDBStem cell-derived models to improve mechanistic understanding and prediction of human drug-induced liver injuryPatient-specific hepatocyte-like cells derived from induced pluripotent stem cells model pazopanib-mediated hepatotoxicityThe ConsensusPathDB interaction database: 2013 update.MicroRNA-122: a novel hepatocyte-enriched in vitro marker of drug-induced cellular toxicity.ToxDB: pathway-level interpretation of drug-treatment dataWind of change challenges toxicological regulators.Xeno-sensing activity of the aryl hydrocarbon receptor in human pluripotent stem cell-derived hepatocyte-like cells.Premalignant alteration assessment in liver-like tissue derived from embryonic stem cells by aristolochic acid I exposure.Modeling human liver biology using stem cell-derived hepatocytes.Computational modeling of drug response with applications to neuroscience.Regulatory toxicology in the twenty-first century: challenges, perspectives and possible solutions.Highly Synchronized Expression of Lineage-Specific Genes during In Vitro Hepatic Differentiation of Human Pluripotent Stem Cell Lines.Development of novel tools for the in vitro investigation of drug-induced liver injury.Inter-laboratory study of human in vitro toxicogenomics-based tests as alternative methods for evaluating chemical carcinogenicity: a bioinformatics perspective.One Standardized Differentiation Procedure Robustly Generates Homogenous Hepatocyte Cultures Displaying Metabolic Diversity from a Large Panel of Human Pluripotent Stem Cells.Pluripotent stem cells: An in vitro model for nanotoxicity assessments.Human hepatocytes derived from pluripotent stem cells: a promising cell model for drug hepatotoxicity screening.Critical differences in toxicity mechanisms in induced pluripotent stem cell-derived hepatocytes, hepatic cell lines and primary hepatocytes.Testing chemical carcinogenicity by using a transcriptomics HepaRG-based model?Transcriptomic responses generated by hepatocarcinogens in a battery of liver-based in vitro models.Hepatic differentiation and maturation of human embryonic stem cells cultured in a perfused three-dimensional bioreactorValidation of Transcriptomics-Based In Vitro Methods.Comparative transcriptomics of hepatic differentiation of human pluripotent stem cells and adult human liver tissue.Toxic Dose prediction of Chemical Compounds to Biomarkers using an ANOVA based Gene Expression AnalysisNetwork and Pathway Analysis of Toxicogenomics DataRobust Co-clustering to Discover Toxicogenomic Biomarkers and Their Regulatory Doses of Chemical Compounds Using Logistic Probabilistic Hidden Variable Model
P2860
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P2860
Human embryonic stem cell derived hepatocyte-like cells as a tool for in vitro hazard assessment of chemical carcinogenicity
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Human embryonic stem cell deri ...... nt of chemical carcinogenicity
@en
Human embryonic stem cell deri ...... t of chemical carcinogenicity.
@nl
type
label
Human embryonic stem cell deri ...... nt of chemical carcinogenicity
@en
Human embryonic stem cell deri ...... t of chemical carcinogenicity.
@nl
prefLabel
Human embryonic stem cell deri ...... nt of chemical carcinogenicity
@en
Human embryonic stem cell deri ...... t of chemical carcinogenicity.
@nl
P2093
P2860
P50
P356
P1476
Human embryonic stem cell deri ...... nt of chemical carcinogenicity
@en
P2093
Agustin Lahoz
Atanas Kamburov
Gabriella Brolén
Gustav Eriksson
Hans Gmuender
Jane Synnergren
Joost van Delft
José Castell
Mireia Vilardell
Petter Björquist
P2860
P304
P356
10.1093/TOXSCI/KFR225
P577
2011-08-27T00:00:00Z