Mutational analysis of the transferrin receptor reveals overlapping HFE and transferrin binding sites.
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Mechanism for multiple ligand recognition by the human transferrin receptorHow mammals acquire and distribute iron needed for oxygen-based metabolismN-glycosylation is important for the correct intracellular localization of HFE and its ability to decrease cell surface transferrin bindingHepcidin: regulation of the master iron regulatorRegulation of Iron Metabolism by Hepcidin under Conditions of InflammationTransferrin-mediated cellular iron deliveryMechanisms of mammalian iron homeostasisModulation of hepcidin as therapy for primary and secondary iron overload disorders: preclinical models and approachesThe Crystal Structure of CHIR-AB1: A Primordial Avian Classical Fc ReceptorA computational model of liver iron metabolismHemochromatosis enhances tumor progression via upregulation of intracellular iron in head and neck cancer.Pathophysiological consequences and benefits of HFE mutations: 20 years of research.Molecular mechanisms of hepcidin regulation: implications for the anemia of CKD.Mouse transferrin receptor 1 is the cell entry receptor for mouse mammary tumor virus.Parvovirus infection of cells by using variants of the feline transferrin receptor altering clathrin-mediated endocytosis, membrane domain localization, and capsid-binding domains.A linear lattice model for polyglutamine in CAG-expansion diseasesBiological and clinical aspects of soluble transferrin receptor.Evolutionary reconstructions of the transferrin receptor of Caniforms supports canine parvovirus being a re-emerged and not a novel pathogen in dogsHepcidin induction by transgenic overexpression of Hfe does not require the Hfe cytoplasmic tail, but does require hemojuvelin.Hepcidin--central regulator of iron metabolism.Interaction of the hereditary hemochromatosis protein HFE with transferrin receptor 2 is required for transferrin-induced hepcidin expression.Ferristatin II promotes degradation of transferrin receptor-1 in vitro and in vivo.Purified feline and canine transferrin receptors reveal complex interactions with the capsids of canine and feline parvoviruses that correspond to their host rangesMolecular mechanisms and regulation of iron transport.Residues in the apical domain of the feline and canine transferrin receptors control host-specific binding and cell infection of canine and feline parvoviruses.Mechanisms of HFE-induced regulation of iron homeostasis: Insights from the W81A HFE mutation.Hereditary hemochromatosis and transferrin receptor 2The long history of iron in the Universe and in health and disease.Anti-PolyQ Antibodies Recognize a Short PolyQ Stretch in Both Normal and Mutant Huntingtin Exon 1.Different mechanisms of antibody-mediated neutralization of parvoviruses revealed using the Fab fragments of monoclonal antibodies.Transgenic HFE-dependent induction of hepcidin in mice does not require transferrin receptor-2.Erythrocytic Iron Deficiency Enhances Susceptibility to Plasmodium chabaudi Infection in Mice Carrying a Missense Mutation in Transferrin Receptor 1HFE gene in primary and secondary hepatic iron overload.Liver iron transportThe transferrin receptor modulates Hfe-dependent regulation of hepcidin expression.Molecular regulation of hepatic expression of iron regulatory hormone hepcidin.Liver-gut axis in the regulation of iron homeostasis.Transferrin-a modulates hepcidin expression in zebrafish embryos.Inequivalent contribution of the five tryptophan residues in the C-lobe of human serum transferrin to the fluorescence increase when iron is released.A general map of iron metabolism and tissue-specific subnetworks.
P2860
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P2860
Mutational analysis of the transferrin receptor reveals overlapping HFE and transferrin binding sites.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Mutational analysis of the tra ...... and transferrin binding sites.
@en
Mutational analysis of the tra ...... and transferrin binding sites.
@nl
type
label
Mutational analysis of the tra ...... and transferrin binding sites.
@en
Mutational analysis of the tra ...... and transferrin binding sites.
@nl
prefLabel
Mutational analysis of the tra ...... and transferrin binding sites.
@en
Mutational analysis of the tra ...... and transferrin binding sites.
@nl
P2093
P356
P1476
Mutational analysis of the tra ...... and transferrin binding sites.
@en
P2093
A M Giannetti
J R Pierce
J S Nangiana
L P Weiner
M J Bennett
P J Bjorkman
P304
P356
10.1006/JMBI.2001.5048
P407
P577
2001-10-01T00:00:00Z