Disruption of mycobactin biosynthesis leads to attenuation of Mycobacterium tuberculosis for growth and virulence.
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Structure and Functional Diversity of GCN5-Related N-Acetyltransferases (GNAT)Structure, Biochemistry, and Inhibition of Essential 4′-Phosphopantetheinyl Transferases from Two Species of MycobacteriaLipidomic analysis links mycobactin synthase K to iron uptake and virulence in M. tuberculosisThe reduced genome of the Francisella tularensis live vaccine strain (LVS) encodes two iron acquisition systems essential for optimal growth and virulenceMycobacterial phylogenomics: an enhanced method for gene turnover analysis reveals uneven levels of gene gain and loss among species and gene familiesApurinic/apyrimidinic endonucleases of Mycobacterium tuberculosis protect against DNA damage but are dispensable for the growth of the pathogen in guinea pigs.bioA mutant of Mycobacterium tuberculosis shows severe growth defect and imparts protection against tuberculosis in guinea pigs.Expanding the results of a high throughput screen against an isochorismate-pyruvate lyase to enzymes of a similar scaffold or mechanism.Curation, integration and visualization of bacterial virulence factors in PATRICThe ESX-3 secretion system is necessary for iron and zinc homeostasis in Mycobacterium tuberculosis.Secretory phosphatases deficient mutant of Mycobacterium tuberculosis imparts protection at the primary site of infection in guinea pigs.A novel antimycobacterial compound acts as an intracellular iron chelator.Mycobacterium tuberculosis DosR is required for activity of the PmbtB and PmbtI promoters under hypoxiaProtein kinase A (PknA) of Mycobacterium tuberculosis is independently activated and is critical for growth in vitro and survival of the pathogen in the host.Insight into the evolution and origin of leprosy bacilli from the genome sequence of Mycobacterium lepromatosisThe tuberculosis drug discovery and development pipeline and emerging drug targets.Comparative genomics between human and animal associated subspecies of the Mycobacterium avium complex: a basis for pathogenicity.Depletion of M. tuberculosis GlmU from Infected Murine Lungs Effects the Clearance of the Pathogen.Mycobacteria, metals, and the macrophageComparative Genomic Analysis Reveals a Possible Novel Non-Tuberculous Mycobacterium Species with High Pathogenic Potential.Biomarkers for Tuberculosis Based on Secreted, Species-Specific, Bacterial Small MoleculesSynthesis and Pharmacokinetic Evaluation of Siderophore Biosynthesis Inhibitors for Mycobacterium tuberculosisStereocontrolled Synthesis of a Potential Transition-State Inhibitor of the Salicylate Synthase MbtI from Mycobacterium tuberculosis.Investigation and conformational analysis of fluorinated nucleoside antibiotics targeting siderophore biosynthesis.Separable roles for Mycobacterium tuberculosis ESX-3 effectors in iron acquisition and virulence.Functions and importance of mycobacterial extracellular vesiclesIron in intracellular infection: to provide or to deprive?KefB inhibits phagosomal acidification but its role is unrelated to M. tuberculosis survival in host.Self-poisoning of Mycobacterium tuberculosis by interrupting siderophore recycling.Role for Mycobacterium tuberculosis membrane vesicles in iron acquisition.Biosynthesis of mycobacterial lipids by polyketide synthases and beyond.Tuberculosis drug discovery and emerging targets.Macrophage defense mechanisms against intracellular bacteria.Iron Acquisition in Mycobacterium avium subsp. paratuberculosis.The Capacity of Mycobacterium tuberculosis To Survive Iron Starvation Might Enable It To Persist in Iron-Deprived Microenvironments of Human Granulomas.Enterobacteria secrete an inhibitor of Pseudomonas virulence during clinical bacteriuria.Organ pathology in the absence of bacteria?Design, synthesis, and biological evaluation of α-hydroxyacyl-AMS inhibitors of amino acid adenylation enzymes.Conformationally Constrained Cinnolinone Nucleoside Analogues as Siderophore Biosynthesis Inhibitors for Tuberculosis.Altered Mycobacterium tuberculosis Cell Wall Metabolism and Physiology Associated With RpoB Mutation H526D.
P2860
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P2860
Disruption of mycobactin biosynthesis leads to attenuation of Mycobacterium tuberculosis for growth and virulence.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Disruption of mycobactin biosy ...... osis for growth and virulence.
@en
Disruption of mycobactin biosy ...... osis for growth and virulence.
@nl
type
label
Disruption of mycobactin biosy ...... osis for growth and virulence.
@en
Disruption of mycobactin biosy ...... osis for growth and virulence.
@nl
prefLabel
Disruption of mycobactin biosy ...... osis for growth and virulence.
@en
Disruption of mycobactin biosy ...... osis for growth and virulence.
@nl
P2093
P2860
P356
P1476
Disruption of mycobactin biosy ...... osis for growth and virulence.
@en
P2093
Akshay Rohilla
Anil K Tyagi
Aparna Khera
P Vineel Reddy
Priyanka Chauhan
Ritika Kar
Rupangi Verma Puri
P2860
P304
P356
10.1093/INFDIS/JIT250
P407
P577
2013-06-20T00:00:00Z