Purification from hamster cells of the multifunctional protein that initiates de novo synthesis of pyrimidine nucleotides.
about
The human Rad9 checkpoint protein stimulates the carbamoyl phosphate synthetase activity of the multifunctional protein CADPhosphorylation and activation of hamster carbamyl phosphate synthetase II by cAMP-dependent protein kinase. A novel mechanism for regulation of pyrimidine nucleotide biosynthesisMammalian dihydroorotase: nucleotide sequence, peptide sequences, and evolution of the dihydroorotase domain of the multifunctional protein CADIntegrated allosteric regulation in the S. cerevisiae carbamylphosphate synthetase - aspartate transcarbamylase multifunctional proteinTranscriptional repression of human cad gene by hypoxia inducible factor-1alphaStructure of the catalytic chain ofMethanococcus jannaschiiaspartate transcarbamoylase in a hexagonal crystal form: insights into the path of carbamoyl phosphate to the active site of the enzymeDynamics of the cellular metabolome during human cytomegalovirus infectionOligomeric structure of the multifunctional protein CAD that initiates pyrimidine biosynthesis in mammalian cellsConstruction of a cDNA to the hamster CAD gene and its application toward defining the domain for aspartate transcarbamylase.Genetics and biochemistry of carbamoyl phosphate biosynthesis and its utilization in the pyrimidine biosynthetic pathwayMammalian aspartate transcarbamylase (ATCase): sequence of the ATCase domain and interdomain linker in the CAD multifunctional polypeptide and properties of the isolated domain.Organization of the Rudimentary Wing Locus in DROSOPHILA MELANOGASTER. I. the Isolation and Partial Characterization of Mutants Induced with Ethyl Methanesulfonate, Icr-170 and X RaysRheb protein binds CAD (carbamoyl-phosphate synthetase 2, aspartate transcarbamoylase, and dihydroorotase) protein in a GTP- and effector domain-dependent manner and influences its cellular localization and carbamoyl-phosphate synthetase (CPSase) acIdentification of broad-spectrum antiviral compounds and assessment of the druggability of their target for efficacy against respiratory syncytial virus (RSV)Antisense-mediated depletion of p300 in human cells leads to premature G1 exit and up-regulation of c-MYC.Demonstration, by somatic cell genetics, of coordinate regulation of genes for two enzymes of purine synthesis assigned to human chromosome 21.Design, synthesis, and bioactivity of novel inhibitors of E. coli aspartate transcarbamoylase.A single protein catalyzes both N-deacetylation and N-sulfation during the biosynthesis of heparan sulfate.Cloning of a yeast gene coding for arginine-specific carbamoyl-phosphate synthetase.Proteolytically induced changes in the molecular form of the carbamyl phosphate synthetase-uracil-aspartate transcarbamylase complex coded for by the URA2 locus in Saccharomyces cerevisiae.Controlled proteolysis of the multifunctional protein that initiates pyrimidine biosynthesis in mammalian cells: evidence for discrete structural domains.Expression, purification, crystallization and preliminary X-ray diffraction analysis of the dihydroorotase domain of human CAD.Subunit structure of a class A aspartate transcarbamoylase from Pseudomonas fluorescens.Transcriptional regulation of the human CAD gene during myeloid differentiation.Abundant nuclear ribonucleoprotein form of CAD RNA.Escherichia coli aspartate transcarbamylase: a novel marker for studies of gene amplification and expression in mammalian cells.Structure of the gene for CAD, the multifunctional protein that initiates UMP synthesis in Syrian hamster cells.Substitutions in the aspartate transcarbamoylase domain of hamster CAD disrupt oligomeric structureAlteration in structure of multifunctional protein from Chinese hamster ovary cells defective in pyrimidine biosynthesis.Expression, purification, crystallization and preliminary X-ray diffraction analysis of the aspartate transcarbamoylase domain of human CAD.Partial cDNA sequence to a hamster gene corrects defect in Escherichia coli pyrB mutantTranscriptional regulation of genes for ornithine cycle enzymes.The quaternary structure of wheat-germ aspartate transcarbamoylase.Organization of a multifunctional protein in pyrimidine biosynthesis. A domain hypersensitive to proteolysis.Crystallization and preliminary X-ray analysis of aspartate transcarbamoylase from the parasitic protist Trypanosoma cruzi.Nucleotide ligands protect the inter-domain regions of the multifunctional polypeptide CAD against limited proteolysis, and also stabilize the thermolabile part-reactions of the carbamoyl-phosphate synthase II domains within the CAD polypeptide.A protonated histidine residue in a phosphorylation site for cyclic AMP-dependent protein kinase. Comparison of a synthetic peptide with the exposed linking region in the multienzyme polypeptide CADAspartate-90 and arginine-269 of hamster aspartate transcarbamylase affect the oligomeric state of a chimaeric protein with an Escherichia coli maltose-binding domain.Substitutions in hamster CAD carbamoyl-phosphate synthetase alter allosteric response to 5-phosphoribosyl-alpha-pyrophosphate (PRPP) and UTP.Activation of Latent Dihydroorotase from Aquifex aeolicus by Pressure.
P2860
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P2860
Purification from hamster cells of the multifunctional protein that initiates de novo synthesis of pyrimidine nucleotides.
description
1977 nî lūn-bûn
@nan
1977年の論文
@ja
1977年論文
@yue
1977年論文
@zh-hant
1977年論文
@zh-hk
1977年論文
@zh-mo
1977年論文
@zh-tw
1977年论文
@wuu
1977年论文
@zh
1977年论文
@zh-cn
name
Purification from hamster cell ...... sis of pyrimidine nucleotides.
@en
Purification from hamster cell ...... sis of pyrimidine nucleotides.
@nl
type
label
Purification from hamster cell ...... sis of pyrimidine nucleotides.
@en
Purification from hamster cell ...... sis of pyrimidine nucleotides.
@nl
prefLabel
Purification from hamster cell ...... sis of pyrimidine nucleotides.
@en
Purification from hamster cell ...... sis of pyrimidine nucleotides.
@nl
P2093
P1476
Purification from hamster cell ...... sis of pyrimidine nucleotides.
@en
P2093
P304
P407
P577
1977-09-01T00:00:00Z