Collaborating Pathways that Functionally Amplify NOTCH1 Signals in T-Cell Acute Lymphoblastic Leukemia.

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Collaborating Pathways that Functionally Amplify NOTCH1 Signals in T-Cell Acute Lymphoblastic Leukemia.

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2013 nî lūn-bûn

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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Collaborating Pathways that Fu ...... Acute Lymphoblastic Leukemia.

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Collaborating Pathways that Fu ...... Acute Lymphoblastic Leukemia.

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Collaborating Pathways that Fu ...... Acute Lymphoblastic Leukemia.

@en

Collaborating Pathways that Fu ...... Acute Lymphoblastic Leukemia.

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Collaborating Pathways that Fu ...... Acute Lymphoblastic Leukemia.

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Collaborating Pathways that Fu ...... Acute Lymphoblastic Leukemia.

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P1476

Collaborating Pathways that Fu ...... Acute Lymphoblastic Leukemia.

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Mark Y Chiang

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Nancy E Pinnell

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The ubiquitin ligase FBXW7 modulates leukemia-initiating cell activity by regulating MYC stability

Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia.

Perifosine inhibits mammalian target of rapamycin signaling through facilitating degradation of major components in the mTOR axis and induces autophagy

Identification of a conserved negative regulatory sequence that influences the leukemogenic activity of NOTCH1

Structural basis for autoinhibition of Notch

Expression of aberrantly spliced oncogenic ikaros isoforms in childhood acute lymphoblastic leukemia

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.

Phase I study of RO4929097, a gamma secretase inhibitor of Notch signaling, in patients with refractory metastatic or locally advanced solid tumors.

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scholarly article

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P478

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2013-09-02T00:00:00Z

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26998506

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collaboration

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4798248

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