Novel fused pyrimidine and isoquinoline derivatives as potent HIV-1 NNRTIs: a patent evaluation of WO2016105532A1, WO2016105534A1 and WO2016105564A1.

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Further Exploring Solvent-Exposed Tolerant Regions of Allosteric Binding Pocket for Novel HIV-1 NNRTIs Discovery.

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P2860

Novel fused pyrimidine and isoquinoline derivatives as potent HIV-1 NNRTIs: a patent evaluation of WO2016105532A1, WO2016105534A1 and WO2016105564A1.

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2017 nî lūn-bûn

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2017年の論文

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2017年論文

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2017年論文

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2017年論文

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2017年論文

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2017年論文

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2017年论文

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2017年论文

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2017年论文

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Novel fused pyrimidine and iso ...... 16105534A1 and WO2016105564A1.

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Novel fused pyrimidine and iso ...... 16105534A1 and WO2016105564A1.

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Novel fused pyrimidine and iso ...... 16105534A1 and WO2016105564A1.

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Novel fused pyrimidine and iso ...... 16105534A1 and WO2016105564A1.

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Novel fused pyrimidine and iso ...... 16105534A1 and WO2016105564A1.

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P1476

Novel fused pyrimidine and iso ...... 16105534A1 and WO2016105564A1.

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P2093

Dongwei Kang

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Gaochan Wu

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Jiabao Xu

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Peng Zhan

http://www.w3.org/2001/XMLSchema#string

Zhipeng Huo

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P2860

Crystal structures of HIV-1 reverse transcriptase with etravirine (TMC125) and rilpivirine (TMC278): implications for drug design

A comparison of the ability of rilpivirine (TMC278) and selected analogues to inhibit clinically relevant HIV-1 reverse transcriptase mutants

Picomolar Inhibitors of HIV Reverse Transcriptase Featuring Bicyclic Replacement of a Cyanovinylphenyl Group

Picomolar Inhibitors of HIV-1 Reverse Transcriptase: Design and Crystallography of Naphthyl Phenyl Ethers

Non-nucleoside reverse transcriptase inhibitors (NNRTIs), their discovery, development, and use in the treatment of HIV-1 infection: a review of the last 20 years (1989-2009).

Structure-based evaluation of non-nucleoside inhibitors with improved potency and solubility that target HIV reverse transcriptase variants.

Computationally-guided optimization of a docking hit to yield catechol diethers as potent anti-HIV agents

From 4,5,6,7-tetrahydro-5-methylimidazo[4,5,1-jk](1,4)benzodiazepin-2(1H)-one (TIBO) to etravirine (TMC125): fifteen years of research on non-nucleoside inhibitors of HIV-1 reverse transcriptase.

Discovery and crystallography of bicyclic arylaminoazines as potent inhibitors of HIV-1 reverse transcriptase

Design strategies of novel NNRTIs to overcome drug resistance.

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383-391

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scholarly article

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10.1080/13543776.2017.1303046

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English

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Xinyong Liu

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2017-03-09T00:00:00Z

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Novel fused pyrimidine and isoquinoline derivatives as potent HIV-1 NNRTIs: a patent evaluation of WO2016105532A1, WO2016105534A1 and WO2016105564A1.

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P2860

P2860

Novel fused pyrimidine and isoquinoline derivatives as potent HIV-1 NNRTIs: a patent evaluation of WO2016105532A1, WO2016105534A1 and WO2016105564A1.

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P2860

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