Macrolide antibiotics block autophagy flux and sensitize to bortezomib via endoplasmic reticulum stress-mediated CHOP induction in myeloma cells.
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The 26S proteasome is a multifaceted target for anti-cancer therapiesMacrolide Antibiotics Exhibit Cytotoxic Effect under Amino Acid-Depleted Culture Condition by Blocking Autophagy Flux in Head and Neck Squamous Cell Carcinoma Cell LinesTargeting bortezomib-induced aggresome formation using vinorelbine enhances the cytotoxic effect along with ER stress loading in breast cancer cell lines.Repurposing Drugs in Oncology (ReDO)-mebendazole as an anti-cancer agentCombination therapy in combating cancer.Mechanical Stretch Induces Apoptosis Regulator TRB3 in Cultured Cardiomyocytes and Volume-Overloaded HeartCharacterization of aggregate/aggresome structures formed by polyhedrin of Bombyx mori nucleopolyhedrovirusParadoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits.Using Ambystoma mexicanum (Mexican axolotl) embryos, chemical genetics, and microarray analysis to identify signaling pathways associated with tissue regenerationMacrolides sensitize EGFR-TKI-induced non-apoptotic cell death via blocking autophagy flux in pancreatic cancer cell lines.Carfilzomib combined with suberanilohydroxamic acid (SAHA) synergistically promotes endoplasmic reticulum stress in non-small cell lung cancer cell lines.Targeting the integrated networks of aggresome formation, proteasome, and autophagy potentiates ER stress‑mediated cell death in multiple myeloma cells.Repurposing Drugs in Oncology (ReDO)-clarithromycin as an anti-cancer agentRepurposing drugs in oncology (ReDO)-cimetidine as an anti-cancer agentInflammatory and Anti-Inflammatory Equilibrium, Proliferative and Antiproliferative Balance: The Role of Cytokines in Multiple Myeloma.A novel combination of bortezomib, lenalidomide, and clarithromycin produced stringent complete response in refractory multiple myeloma complicated with diabetes mellitus - clinical significance and possible mechanisms: a case report.The cyclin-dependent kinase 4/6 inhibitor, abemaciclib, exerts dose-dependent cytostatic and cytocidal effects and induces autophagy in multiple myeloma cells.Amino acid starvation culture condition sensitizes EGFR-expressing cancer cell lines to gefitinib-mediated cytotoxicity by inducing atypical necroptosis.A randomized placebo-controlled phase II study of clarithromycin or placebo combined with VCD induction therapy prior to high-dose melphalan with stem cell support in patients with newly diagnosed multiple myeloma
P2860
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P2860
Macrolide antibiotics block autophagy flux and sensitize to bortezomib via endoplasmic reticulum stress-mediated CHOP induction in myeloma cells.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Macrolide antibiotics block au ...... OP induction in myeloma cells.
@en
Macrolide antibiotics block au ...... OP induction in myeloma cells.
@nl
type
label
Macrolide antibiotics block au ...... OP induction in myeloma cells.
@en
Macrolide antibiotics block au ...... OP induction in myeloma cells.
@nl
prefLabel
Macrolide antibiotics block au ...... OP induction in myeloma cells.
@en
Macrolide antibiotics block au ...... OP induction in myeloma cells.
@nl
P2093
P2860
P921
P356
P1476
Macrolide antibiotics block au ...... OP induction in myeloma cells.
@en
P2093
Akihiko Gotoh
Akihisa Abe
Akio Tomoda
Keisuke Miyazawa
Masato Inazu
Seiichiro Komatsu
Shota Moriya
Tomohiro Kawaguchi
Xiao-Fang Che
P2860
P304
P356
10.3892/IJO.2013.1870
P577
2013-03-28T00:00:00Z