ETV1 directs androgen metabolism and confers aggressive prostate cancer in targeted mice and patients. - Wikidata - awgldk - TriplyDB

ETV1 directs androgen metabolism and confers aggressive prostate cancer in targeted mice and patients.

ETV1 directs androgen metabolism and confers aggressive prostate cancer in targeted mice and patients.

http://www.wikidata.org/entity/Q39178242

about

Genetic interaction between Tmprss2-ERG gene fusion and Nkx3.1-loss does not enhance prostate tumorigenesis in mouse models A small molecule inhibitor of ETV1, YK-4-279, prevents prostate cancer growth and metastasis in a mouse xenograft model Dissecting the expression landscape of RNA-binding proteins in human cancers Structures of the Ets Protein DNA-binding Domains of Transcription Factors Etv1, Etv4, Etv5, and Fev: DETERMINANTS OF DNA BINDING AND REDOX REGULATION BY DISULFIDE BOND FORMATION.Structured and disordered regions cooperatively mediate DNA-binding autoinhibition of ETS factors ETV1, ETV4 and ETV5.The ETS family member GABPα modulates androgen receptor signalling and mediates an aggressive phenotype in prostate cancer The Effects and Mechanism of YK-4-279 in Combination with Docetaxel on Prostate Cancer.Mouse models of prostate cancer: picking the best model for the question.Histone H2A.Z deregulation in prostate cancer. Cause or effect?A small molecule that binds and inhibits the ETV1 transcription factor oncoprotein Novel RNA hybridization method for the in situ detection of ETV1, ETV4, and ETV5 gene fusions in prostate cancer.Molecular pathways and targets in prostate cancer A Tale of Two Signals: AR and WNT in Development and Tumorigenesis of Prostate and Mammary Gland.The ETS family of oncogenic transcription factors in solid tumours.The Molecular Taxonomy of Primary Prostate Cancer.Osteopontin-c mediates the upregulation of androgen responsive genes in LNCaP cells through PI3K/Akt and androgen receptor signaling.Interaction of the Androgen Receptor, ETV1, and PTEN Pathways in Mouse Prostate Varies with Pathological Stage and Predicts Cancer Progression.Androgen receptor and chemokine receptors 4 and 7 form a signaling axis to regulate CXCL12-dependent cellular motility Specific and redundant activities of ETV1 and ETV4 in prostate cancer aggressiveness revealed by co-overexpression cellular contexts Histone demethylase JMJD2A drives prostate tumorigenesis through transcription factor ETV1.Molecular profiling of ETS and non-ETS aberrations in prostate cancer patients from northern India.ETS transcription factor ERG cooperates with histone demethylase KDM4A.ETV4 promotes metastasis in response to activation of PI3-kinase and Ras signaling in a mouse model of advanced prostate cancer.Differential expression of miR-34b and androgen receptor pathway regulate prostate cancer aggressiveness between African-Americans and Caucasians Maintaining and reprogramming genomic androgen receptor activity in prostate cancer.Detailed longitudinal sampling of glioma stem cells in situ reveals Chr7 gain and Chr10 loss as repeated events in primary tumor formation and recurrence.ERG expression in prostate cancer: biological relevance and clinical implication.ETV4 and AP1 Transcription Factors Form Multivalent Interactions with three Sites on the MED25 Activator-Interacting Domain.c-Myc Antagonises the Transcriptional Activity of the Androgen Receptor in Prostate Cancer Affecting Key Gene Networks.Discovery Proteomics Identifies a Molecular Link between the Coatomer Protein Complex I and Androgen Receptor-dependent Transcription The Germ Cell Gene TDRD1 as an ERG Target Gene and a Novel Prostate Cancer Biomarker.Reduced Erg Dosage Impairs Survival of Hematopoietic Stem and Progenitor Cells.Coordinate loss of MAP3K7 and CHD1 promotes aggressive prostate cancer Suppression of CHK1 by ETS Family Members Promotes DNA Damage Response Bypass and Tumorigenesis.TMPRSS2:ERG blocks neuroendocrine and luminal cell differentiation to maintain prostate cancer proliferation.Growth hormone-releasing hormone antagonists abolish the transactivation of human epidermal growth factor receptors in advanced prostate cancer models.Novel Gemini vitamin D3 analogs: large structure/function analysis and ability to induce antimicrobial peptide.Rationale for the development of alternative forms of androgen deprivation therapy.Deletion of Interstitial Genes between TMPRSS2 and ERG Promotes Prostate Cancer Progression.Upregulation of PSMD10 caused by the JMJD2A histone demethylase.

P2860

Q27311359-423FF30E-2CAD-46F7-A98A-FFF5A84D0FEB Q27322372-4581880B-A43E-43DD-8AFC-608B5F950C42 Q28305624-4009F921-DE03-4EC2-9649-A615222AF15E Q30373611-845E12B1-D3F8-48F3-B8DA-40991B766115 Q33558203-525F70C1-4CA4-494C-B75D-BB1E4CA28236 Q33698635-71799696-3463-47C6-A05F-5FCBAF8D2068 Q33702987-862635BD-02C0-400B-AB08-4D99F91590D0 Q33940867-39FD579A-ECC4-421F-9BC3-337F1422119C Q33962848-EA48C8BE-81F9-4E1C-8AD6-7B412BF4595A Q34132931-2AE60477-1479-48F8-AB0E-CEAFF01953C6 Q34158217-EA8ADA5F-A9F0-4F6E-B13F-B58689C5E1EC Q34365632-6304AC57-DA88-4552-A31E-0860B2BC3FA6 Q34550256-B4D91AAE-E59D-4914-8E15-9BEE766F0F26 Q34555986-734AB3A0-D78B-4829-9B72-B1523EFF4BDF Q34674332-9D644586-4216-4D43-8E9F-CC0A44B68091 Q35167752-98374991-298D-40C2-8293-0AB1CC591EC0 Q35554127-B83D8CDA-82A0-44BB-8FE9-4950E7BAFEF7 Q35605311-4F6F9243-B498-4C3A-B404-D2F07EFDC346 Q35741647-46B2BF2C-B6F2-4C53-9937-D4789379E6AB Q36515134-C7FA0750-6123-40A2-A009-E664EC59DF68 Q36800086-5A61D5EE-A9E9-4375-8DA7-EA43BAB0519B Q36908878-4E056787-9C1F-4CCB-868B-CCCFC1927E7D Q37173209-1503DCA6-6DB7-4BFC-BF73-4A6FBB7A92BB Q37702713-5DC9B75B-84D1-41A3-9EC5-F12E315A1443 Q38190362-F26EEF89-21E6-4A1B-A2AA-CCDD2DCA0965 Q38677899-EF371091-A35C-4B08-A08F-F7ECE747E790 Q38681610-DFA3DF16-8D0B-4B5E-937E-0D35EE732177 Q38696706-987D1951-32BB-4691-8004-F5D3C5F94D22 Q38707571-48481DD9-70C8-4E8E-B160-D5D545A5179E Q38760518-2A4363DA-8DD9-42CD-8755-E0B451F8B62E Q38766041-0492264B-76B8-45EB-A037-12C33868B37E Q38823486-2BB84A6C-76C3-4FE3-AFAF-38324AED4B84 Q38900181-E946715F-6E6C-4E04-A976-2401D322F3C4 Q38912800-5D401914-F382-42C5-A741-3B7AAA0CE4FD Q38952586-C4B395B6-C672-4443-8D2B-CF86CAF709EC Q38977467-410CDA6C-DDD5-40E4-866C-430777BCF68A Q39138273-C3316F28-52A4-49CF-BB96-FFC46615D688 Q39342369-748BF75A-ECDC-4E49-911E-8D7F57C32AF3 Q40908009-A9CE0876-96DD-47E8-82C8-87696A068972 Q41615123-F4791733-2330-471B-B1ED-5E744D153321

P2860

ETV1 directs androgen metabolism and confers aggressive prostate cancer in targeted mice and patients.

http://www.wikidata.org/entity/Q39178242

description

2013 nî lūn-bûn

@nan

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

2013年论文

@zh

2013年论文

@zh-cn

name

ETV1 directs androgen metaboli ...... in targeted mice and patients.

@en

ETV1 directs androgen metaboli ...... in targeted mice and patients.

@nl

type

label

ETV1 directs androgen metaboli ...... in targeted mice and patients.

@en

ETV1 directs androgen metaboli ...... in targeted mice and patients.

@nl

prefLabel

ETV1 directs androgen metaboli ...... in targeted mice and patients.

@en

ETV1 directs androgen metaboli ...... in targeted mice and patients.

@nl

P1433

Q39178242-5A1439C6-36C9-4DE1-B6BE-61902ECBEAEE

P1476

Q39178242-B5957FAE-809D-40A4-ADF3-8F1B16430041

P2093

Q39178242-0D23D817-F0D9-4919-8743-DFB92688C69A

Q39178242-13A921FF-E597-4831-8B6B-754D9F4DF306

Q39178242-55A6AD92-6A41-4C5C-BB45-F16085F3647A

Q39178242-81E05235-51B2-46A3-AE5B-4C2D7C1FA7CB

Q39178242-8FBF7040-6BA7-4A80-A5ED-42DF3D51FBB2

Q39178242-91AB128F-0192-4AF0-899A-60656A0CD79E

Q39178242-96FB9253-FF14-4B47-A19C-E8ACB2045661

Q39178242-AED73B3B-36F9-42EF-9047-60CC6953FB12

Q39178242-B45647CD-3D06-4AFF-9318-574724C9FA8B

Q39178242-D0FDDE08-C2DB-45E6-9377-3495E2E4E2DE

P2860

Q39178242-00AD01C5-5599-40A6-8403-51FB1429EF94

Q39178242-0373DAB7-0E00-4E4D-BF95-1320104F983C

Q39178242-101A38B6-5667-45C9-86A9-943F5015B310

Q39178242-122F0FE2-1F24-431B-B54D-21FC38C53E6D

Q39178242-13A46FCB-7A97-48A8-8511-C4CBE8399E46

Q39178242-1D471712-B1FE-41C7-9DA8-B5DB75BB4452

Q39178242-23A435B1-7492-4BF8-B363-5CC99DCEC9E3

Q39178242-24ADE431-8452-4857-900B-C43F1A4620E8

Q39178242-2CB2B21F-CA93-4FFA-B2F3-0B263647C35E

Q39178242-2E07535E-9057-4604-9666-25BFA316BB52

P304

Q39178242-6D3B2666-D4EC-40FA-9181-93D783D0CFD6

P31

Q39178242-EE677D24-A1C2-4F98-A2CF-7E75C7E4744A

P356

Q39178242-E766CDDD-B426-4742-AF25-EA8EB074286E

P433

Q39178242-8BAFCB96-CD87-4EBC-8D28-990BA3FF13B2

P478

Q39178242-E65BDDC4-8F7A-4181-86F2-B74D409A6AD1

P50

Q39178242-6D479AB6-9736-41D4-A178-388F9F662AC1

Q39178242-7BC30D14-C3CC-47BD-8518-6E1280766FC6

Q39178242-9A19C015-30DB-4423-B08A-6CD5FD278835

Q39178242-AF5C546F-88D7-4FF5-8552-05C5A62526B4

P577

Q39178242-D51E86B1-AD44-454F-AE55-0E377AF62C1F

P5875

Q39178242-D11217B3-D514-42CC-9EB7-8C3CFA56D382

P698

Q39178242-544CFD73-1719-4C19-B62E-1A097EBDB21C

P921

Q39178242-87FCE818-1214-4226-8E2F-B7CD980913ED

P932

Q39178242-5E587A17-324E-4BC0-AB9E-0B07E18BF663

P356

P1433

Genes & Development

P1476

ETV1 directs androgen metaboli ...... in targeted mice and patients.

@en

P2093

Douglas E Linn

http://www.w3.org/2001/XMLSchema#string

Esther Baena

http://www.w3.org/2001/XMLSchema#string

Frank J Godinho

http://www.w3.org/2001/XMLSchema#string

Guo-Cheng Yuan

http://www.w3.org/2001/XMLSchema#string

Jonghwan Kim

http://www.w3.org/2001/XMLSchema#string

Melanie J Hamblen

http://www.w3.org/2001/XMLSchema#string

Minh Nguyen

http://www.w3.org/2001/XMLSchema#string

Roderick T Bronson

http://www.w3.org/2001/XMLSchema#string

Stuart H Orkin

http://www.w3.org/2001/XMLSchema#string

Xin Zhang

http://www.w3.org/2001/XMLSchema#string

P2860

ETS transcription factors control transcription of EZH2 and epigenetic silencing of the tumor suppressor gene Nkx3.1 in prostate cancer

An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

Gene expression profiling predicts clinical outcome of prostate cancer

Efficient biotinylation and single-step purification of tagged transcription factors in mammalian cells and transgenic mice

Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.

A comparison of normalization methods for high density oligonucleotide array data based on variance and bias

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

Determination of cDNA, gene structure and chromosomal localization of the novel human 17beta-hydroxysteroid dehydrogenase type 7(1)

Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing

P304

683-698

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1101/GAD.211011.112

http://www.w3.org/2001/XMLSchema#string

P433

6

http://www.w3.org/2001/XMLSchema#string

P478

27

http://www.w3.org/2001/XMLSchema#string

P50

Lorelei A Mucci

P577

2013-03-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

236064826

http://www.w3.org/2001/XMLSchema#string

P698

23512661

http://www.w3.org/2001/XMLSchema#string

P921

P932

3613614

http://www.w3.org/2001/XMLSchema#string