3D pancreatic carcinoma spheroids induce a matrix-rich, chemoresistant phenotype offering a better model for drug testing. - Wikidata - awgldk - TriplyDB

3D pancreatic carcinoma spheroids induce a matrix-rich, chemoresistant phenotype offering a better model for drug testing.

3D pancreatic carcinoma spheroids induce a matrix-rich, chemoresistant phenotype offering a better model for drug testing.

http://www.wikidata.org/entity/Q39187713

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Three-dimensional lung tumor microenvironment modulates therapeutic compound responsiveness in vitro--implication for drug development Emerging concepts in pancreatic cancer medicine: targeting the tumor stroma Emerging roles of microRNAs in pancreatic cancer diagnosis, therapy and prognosis (Review)Desmoplasia and chemoresistance in pancreatic cancer 3D microtumors in vitro supported by perfused vascular networks.Ellipsoid Segmentation Model for Analyzing Light-Attenuated 3D Confocal Image Stacks of Fluorescent Multi-Cellular Spheroids Organoids as a Model for Colorectal Cancer Generation of Homogenous Three-Dimensional Pancreatic Cancer Cell Spheroids Using an Improved Hanging Drop Technique Targeting Colorectal Cancer Proliferation, Stemness and Metastatic Potential Using Brassicaceae Extracts Enriched in Isothiocyanates: A 3D Cell Model-Based Study.Microenvironmental regulation of therapeutic response in cancer The multiple facets of drug resistance: one history, different approaches.Hypoxia Responsive, Tumor Penetrating Lipid Nanoparticles for Delivery of Chemotherapeutics to Pancreatic Cancer Cell Spheroids.Mmp-9 responsive PEG cleavable nanovesicles for efficient delivery of chemotherapeutics to pancreatic cancer.DNA damage-induced ephrin-B2 reverse signaling promotes chemoresistance and drives EMT in colorectal carcinoma harboring mutant p53 Spherical cancer models in tumor biology.Targeting insulin-like growth factor 1 receptor inhibits pancreatic cancer growth and metastasis.Challenges and opportunities toward enabling phenotypic screening of complex and 3D cell models.Histamine-functionalized copolymer micelles as a drug delivery system in 2D and 3D models of breast cancer.Formation of stable small cell number three-dimensional ovarian cancer spheroids using hanging drop arrays for preclinical drug sensitivity assays.An Evaluation of Matrix-Containing and Humanised Matrix-Free 3-Dimensional Cell Culture Systems for Studying Breast Cancer High throughput and automatic colony formation assay based on impedance measurement technique.Inhibition of Lysyl Oxidases Improves Drug Diffusion and Increases Efficacy of Cytotoxic Treatment in 3D Tumor Models Interplay between cadherins and α2β1 integrin differentially regulates melanoma cell invasion.Culture phases, cytotoxicity and protein expressions of agarose hydrogel induced Sp2/0, A549, MCF-7 cell line 3D cultures Modeling pancreatic cancer with organoids Applying Small Molecule Signal Transducer and Activator of Transcription-3 (STAT3) Protein Inhibitors as Pancreatic Cancer Therapeutics Influence of TP53 and CDH1 genes in hepatocellular cancer spheroid formation and culture: a model system to understand cancer cell growth mechanics Liquid-based three-dimensional tumor models for cancer research and drug discovery.Imaging Sensitivity of Quiescent Cancer Cells to Metabolic Perturbations in Bone Marrow Spheroids Phospho-Akt overexpression is prognostic and can be used to tailor the synergistic interaction of Akt inhibitors with gemcitabine in pancreatic cancer.Mutant p53 drives pancreatic cancer metastasis through cell-autonomous PDGF receptor β signaling Three-dimensional cancer models mimic cell-matrix interactions in the tumour microenvironment.Three-dimensional models of cancer for pharmacology and cancer cell biology: capturing tumor complexity in vitro/ex vivo.Recapitulating the human tumor microenvironment: Colon tumor-derived extracellular matrix promotes angiogenesis and tumor cell growth.Stromal biology and therapy in pancreatic cancer: a changing paradigm.Combined AURKA and H3K9 Methyltransferase Targeting Inhibits Cell Growth By Inducing Mitotic Catastrophe.Stroma-regulated HMGA2 is an independent prognostic marker in PDAC and AAC.Novel 3-D cell culture system for in vitro evaluation of anticancer drugs under anchorage-independent conditions.The third dimension: new developments in cell culture models for colorectal research.Three-dimensional culture systems in cancer research: Focus on tumor spheroid model.

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3D pancreatic carcinoma spheroids induce a matrix-rich, chemoresistant phenotype offering a better model for drug testing.

http://www.wikidata.org/entity/Q39187713

description

2013 nî lūn-bûn

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name

3D pancreatic carcinoma sphero ...... better model for drug testing.

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3D pancreatic carcinoma sphero ...... better model for drug testing.

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type

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3D pancreatic carcinoma sphero ...... better model for drug testing.

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3D pancreatic carcinoma sphero ...... better model for drug testing.

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3D pancreatic carcinoma sphero ...... better model for drug testing.

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3D pancreatic carcinoma sphero ...... better model for drug testing.

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1471-2407-13-95

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3D pancreatic carcinoma sphero ...... better model for drug testing.

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Annika Wagman

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Caroline Verbeke

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Johannes Eimer

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Michael-Robin Witt

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Paola Longati

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Rune Toftgård

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Stefan Rehnmark

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Xiaohui Jia

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P2860

The Hallmarks of Cancer

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

miR-146a suppresses invasion of pancreatic cancer cells

Identification of microRNA-21 as a biomarker for chemoresistance and clinical outcome following adjuvant therapy in resectable pancreatic cancer

Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice

Spheroid-based drug screen: considerations and practical approach

Responses of fibroblasts to anchorage of dorsal extracellular matrix receptors.

Profiling of 95 microRNAs in pancreatic cancer cell lines and surgical specimens by real-time PCR analysis

Cloning and expression analysis of the mouse stroma marker Snep encoding a novel nidogen domain protein.

Biomimetic microenvironment modulates neural stem cell survival, migration, and differentiation

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1471-2407-13-95

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10.1186/1471-2407-13-95

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Johannes-Matthias Löhr

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235749566

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1031822794

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3617005

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