Fragment-based discovery of 8-hydroxyquinoline inhibitors of the HIV-1 integrase-lens epithelium-derived growth factor/p75 (IN-LEDGF/p75) interaction.
about
A New Class of Allosteric HIV-1 Integrase Inhibitors Identified by Crystallographic Fragment Screening of the Catalytic Core DomainDiscovery of a Potent Anti-tumor Agent through Regioselective Mono-N-acylation of 7H-Pyrrolo[3,2-f]quinazoline-1,3-diamine.State-of-the-art strategies for targeting protein-protein interactions by small-molecule inhibitors.Novel Scaffold Identification of mGlu1 Receptor Negative Allosteric Modulators Using a Hierarchical Virtual Screening Approach.Progress in HIV-1 Integrase Inhibitors: A Review of their Chemical Structure Diversity.LEDGINs, non-catalytic site inhibitors of HIV-1 integrase: a patent review (2006 - 2014)."Old Dogs with New Tricks": exploiting alternative mechanisms of action and new drug design strategies for clinically validated HIV targets.Fragment-based approaches to anti-HIV drug discovery: state of the art and future opportunities.Identification of small peptides inhibiting the integrase-LEDGF/p75 interaction through targeting the cellular co-factor.Intracellular immunization against HIV infection with an intracellular antibody that mimics HIV integrase binding to the cellular LEDGF protein.A new quinoline BRD4 inhibitor targets a distinct latent HIV-1 reservoir for re-activation from other 'shock' drugs.Recent advances in the discovery of small-molecule inhibitors of HIV-1 integrase
P2860
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P2860
Fragment-based discovery of 8-hydroxyquinoline inhibitors of the HIV-1 integrase-lens epithelium-derived growth factor/p75 (IN-LEDGF/p75) interaction.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Fragment-based discovery of 8- ...... 75 (IN-LEDGF/p75) interaction.
@en
Fragment-based discovery of 8- ...... lium-derived growth factor/p75
@nl
type
label
Fragment-based discovery of 8- ...... 75 (IN-LEDGF/p75) interaction.
@en
Fragment-based discovery of 8- ...... lium-derived growth factor/p75
@nl
prefLabel
Fragment-based discovery of 8- ...... 75 (IN-LEDGF/p75) interaction.
@en
Fragment-based discovery of 8- ...... lium-derived growth factor/p75
@nl
P2093
P356
P1476
Fragment-based discovery of 8- ...... 75 (IN-LEDGF/p75) interaction.
@en
P2093
Bikash Debnath
Erik Serrao
Hiroyuki Otake
Nouri Neamati
Yuting Kuang
P304
P356
10.1021/JM301632E
P407
P577
2013-03-18T00:00:00Z