Regression of lung cancer by hypoxia-sensitizing ruthenium polypyridyl complexes. - Wikidata - awgldk - TriplyDB

Regression of lung cancer by hypoxia-sensitizing ruthenium polypyridyl complexes.

Regression of lung cancer by hypoxia-sensitizing ruthenium polypyridyl complexes.

http://www.wikidata.org/entity/Q39188111

about

Cellular and cell-free studies of catalytic DNA cleavage by ruthenium polypyridyl complexes containing redox-active intercalating ligands.Novel compound 1,3-bis (3,5-dichlorophenyl) urea inhibits lung cancer progression Multifaceted interplay between lipophilicity, protein interaction and luminescence parameters of non-intercalative ruthenium(II) polypyridyl complexes controlling cellular imaging and cytotoxic properties.Ultrafast photo-induced ligand solvolysis of cis-[Ru(bipyridine)2(nicotinamide)2](2+): experimental and theoretical insight into its photoactivation mechanism.Temperature and oxygen-concentration dependence of singlet oxygen production by RuPhen as induced by quasi-continuous excitation.Light-Sensitive Ruthenium Complex-Loaded Cross-linked Polymeric Nanoassemblies for the Treatment of Cancer Metallomics insights into the programmed cell death induced by metal-based anticancer compounds.Bis(dipyridophenazine)(2-(2'-pyridyl)pyrimidine-4-carboxylic acid)ruthenium(II) hexafluorophosphate: a lesson in stubbornness.Excited-State Dynamics of a Two-Photon-Activatable Ruthenium Prodrug.A ruthenium polypyridyl intercalator stalls DNA replication forks, radiosensitizes human cancer cells and is enhanced by Chk1 inhibition.Photochemical and Photobiological Activity of Ru(II) Homoleptic and Heteroleptic Complexes Containing Methylated Bipyridyl-type Ligands.Solvent and Copper Ion-Induced Synthesis of Pyridyl-Pyrazole-3-One Derivatives: Crystal Structure, Cytotoxicity.Synthesis, DNA Cleavage Activity, Cytotoxicity, Acetylcholinesterase Inhibition, and Acute Murine Toxicity of Redox-Active Ruthenium(II) Polypyridyl Complexes.The development of ruthenium(ii) polypyridyl complexes and conjugates for in vitro cellular and in vivo applications.Monomeric and dimeric coordinatively saturated and substitutionally inert Ru(ii) polypyridyl complexes as anticancer drug candidates.A three-in-one-bullet for oesophageal cancer: replication fork collapse, spindle attachment failure and enhanced radiosensitivity generated by a ruthenium(ii) metallo-intercalator.Endosomes: guardians against [Ru(Phen)3]2+ photo-action in endothelial cells during in vivo pO2 detection?Photodriven Multi-electron Storage in Disubstituted Ru(II) Dppz Analogues.DNA Intercalating RuIIPolypyridyl Complexes as Effective Photosensitizers in Photodynamic Therapy

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P2860

Regression of lung cancer by hypoxia-sensitizing ruthenium polypyridyl complexes.

http://www.wikidata.org/entity/Q39188111

description

2013 nî lūn-bûn

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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2013年论文

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2013年论文

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name

Regression of lung cancer by hypoxia-sensitizing ruthenium polypyridyl complexes.

@en

Regression of lung cancer by hypoxia-sensitizing ruthenium polypyridyl complexes.

@nl

type

label

Regression of lung cancer by hypoxia-sensitizing ruthenium polypyridyl complexes.

@en

Regression of lung cancer by hypoxia-sensitizing ruthenium polypyridyl complexes.

@nl

prefLabel

Regression of lung cancer by hypoxia-sensitizing ruthenium polypyridyl complexes.

@en

Regression of lung cancer by hypoxia-sensitizing ruthenium polypyridyl complexes.

@nl

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1535-7163.MCT-12-1130

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Molecular Cancer Therapeutics

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Regression of lung cancer by hypoxia-sensitizing ruthenium polypyridyl complexes.

@en

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Abhishek Yadav

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Adam S Dayoub

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Arthi Krishnan

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Doyle L Hawkins

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Frederick M MacDonnell

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Sanjay Awasthi

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Sharad S Singhal

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Sushma Yadav

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Thamara Janaratne

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P2860

DNA cleavage by the photolysis of cyclopentadienyl metal complexes: mechanistic studies and sequence selectivity of strand scission by CpW(CO)3CH3

Biological activity of complex ions.

Pharmacokinetics of a novel anticancer ruthenium complex (KP1019, FFC14A) in a phase I dose-escalation study.

INHIBITION OF LANDSCHUETZ ASCITES TUMOUR GROWTH BY METAL CHELATES DERIVED FROM 3,4,7,8-TETRAMETHYL-1,10-PHENANTHROLINE.

DNA binding mode of ruthenium complexes and relationship to tumor cell toxicity.

Antitumour metal compounds: more than theme and variations.

KP1019, a new redox-active anticancer agent--preclinical development and results of a clinical phase I study in tumor patients.

Mechanism of cellular uptake of a ruthenium polypyridyl complex.

Selective mitochondrial accumulation of cytotoxic dinuclear polypyridyl ruthenium(II) complexes.

Nuclear permeable ruthenium(II) β-carboline complexes induce autophagy to antagonize mitochondrial-mediated apoptosis.

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10.1158/1535-7163.MCT-12-1130

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