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Derivatives of the new ring system indolo[1,2-c]benzo[1,2,3]triazine with potent antitumor and antimicrobial activityIndolo[3,2-c]cinnolines with antiproliferative, antifungal, and antibacterial activityInside the Hsp90 inhibitors binding mode through induced fit docking.DNA minor groove binders: an overview on molecular modeling and QSAR approaches.Molecular modeling approaches in the discovery of new drugs for anti-cancer therapy: the investigation of p53-MDM2 interaction and its inhibition by small molecules.Hsp60, a novel target for antitumor therapy: structure-function features and prospective drugs design.Zinc complexes as fluorescent chemosensors for nucleic acids: new perspectives for a "boring" element.Molecular dynamics, dynamic site mapping, and highthroughput virtual screening on leptin and the Ob receptor as anti-obesity target.Synthesis, antiproliferative activity, and in silico insights of new 3-benzoylamino-benzo[b]thiophene derivatives.An unexpected Dimroth rearrangement leading to annelated thieno[3,2-d][1,2,3]triazolo[1,5-a]pyrimidines with potent antitumor activity.Exploring the anticancer potential of pyrazolo[1,2-a]benzo[1,2,3,4]tetrazin-3-one derivatives: the effect on apoptosis induction, cell cycle and proliferation.Synthesis and biological activities of a new class of heat shock protein 90 inhibitors, designed by energy-based pharmacophore virtual screening.New annelated thieno[2,3-e][1,2,3]triazolo[1,5-a]pyrimidines, with potent anticancer activity, designed through VLAK protocol.Lead optimization through VLAK protocol: new annelated pyrrolo-pyrimidine derivatives as antitumor agents.Design and synthesis of 4-substituted indolo[3,2-e][1,2,3]triazolo[1,5-a]pyrimidine derivatives with antitumor activity.Isoindolo[2,1-c]benzo[1,2,4]triazines: a new ring system with antiproliferative activity.Synthesis and photochemotherapeutic activity of thiopyrano[2,3-e]indol-2-ones.1-Methyl-3H-pyrazolo[1,2-a]benzo[1,2,3,4]tetrazin-3-ones. Design, synthesis, and biological activity of new antitumor agents.Synthesis and antiproliferative activity of [1,2,3,5]tetrazino[5,4-a]indoles, a new class of azolo-tetrazinones.Pyrrolo[1,2-f]phenanthridines and related non-rigid analogues as antiviral agents.In vitro and in silico studies of polycondensed diazine systems as anti-parasitic agents.Pyrrolo[2,1-c][1,2,4]triazines from 2-diazopyrroles: synthesis and antiproliferative activity.Pyrrolo[2,1-d][1,2,3,5]tetrazine-4(3H)-ones, a new class of azolotetrazines with potent antitumor activity.Pyrrolo[2,3-h]quinolinones: synthesis and photochemotherapic activity.3D-QSAR pharmacophore modeling and in silico screening of new Bcl-xl inhibitors.Annelated pyrrolo-pyrimidines from amino-cyanopyrroles and BMMAs as leads for new DNA-interactive ring systems.The interaction of Schiff Base complexes of nickel(II) and zinc(II) with duplex and G-quadruplex DNA.New benzothieno[3,2-d]-1,2,3-triazines with antiproliferative activity: synthesis, spectroscopic studies, and biological activity.IKK-beta inhibitors: an analysis of drug-receptor interaction by using molecular docking and pharmacophore 3D-QSAR approaches.Pyrrolo[2,1-d][1,2,3,5]tetrazinones deaza analogues of temozolomide with potent antitumor activity2-Diazoindoles: building blocks for the synthesis of antineoplastic agentsMolecular docking approach on the Topoisomerase I inhibitors series included in the NCI anti-cancer agents mechanism databaseDocking and multivariate methods to explore HIV-1 drug-resistance: a comparative analysisA general treatment of solubility. 3. Principal component analysis (PCA) of the solubilities of diverse solutes in diverse solventsMolecular dynamics studies on HIV-1 protease: a comparison of the flap motions between wild type protease and the M46I/G51D double mutantA multivariate analysis of HIV-1 protease inhibitors and resistance induced by mutationReceptor-guided 3D-QSAR approach for the discovery of c-kit tyrosine kinase inhibitorsIn-silico screening of new potential Bcl-2/Bcl-xl inhibitors as apoptosis modulatorsPrincipal component analysis on molecular descriptors as an alternative point of view in the search of new Hsp90 inhibitorsMolecular dynamics studies on Mdm2 complexes: an analysis of the inhibitor influence
P50
Q28369366-6CA381AF-2130-4F86-B053-8932CE3BF4CFQ28372692-24001F5D-DEEA-4890-903A-B3B2F35EC72DQ34904539-5322BA8C-6F6C-4C64-8380-825618E6A979Q36907324-F0FDACB7-919E-4912-92EA-5E86D5E24037Q37776282-F38EDA64-30A1-4524-B869-8FF27C7D9188Q38054858-92F6DF3D-FE20-47AC-94D7-A53AAAC68F35Q38265666-71750E83-89E8-47FC-B641-2BDA44A2AFCEQ38307338-633C7E25-2597-43F0-999B-4DD2BF9111DFQ38930962-2DB9DFD7-ADF1-4DC5-B362-4124D4ACFA78Q39142343-8E3588C7-F26F-46A1-B5BB-227F3FA8A556Q39156263-751802E9-AECE-499D-BEDA-7A7A481306CDQ39177171-D9600251-6A92-4537-86AA-15CFAD367032Q39197222-72049A0A-1378-4214-B3DB-7A62FDE939F5Q39297579-31B9F8E7-83DE-48DD-A4BE-E83A5BE6E887Q40001725-7F4090B8-D1EB-496E-A89A-DF5632B61D22Q40215826-F9D0CBB6-450E-4FF5-974F-DDAD78E92411Q40433831-EB732043-8A6B-49AF-A5DF-03789A291923Q40435753-FE16F913-5FE8-4483-B894-DAC80FE3747EQ40480853-5E35CC8F-7DCF-4785-98CD-F354680EEC3AQ40751264-97CB92E9-6978-4A0D-B5EA-478D0DDCFD45Q42722703-7779B7CA-F6D7-4FC0-B85B-A372DDD688FCQ43921822-4C3EE0ED-ED42-41CA-8055-E9A3DDF83095Q44433018-211F4544-9EC3-46CB-A143-1D7561DA5A42Q44520604-5B747570-9E61-4CD6-93E0-FBF3383BDD92Q44950259-97BC04FA-27D3-4758-A8F7-3458D05F6D26Q45255802-7802F649-5ECC-445E-8B42-20ADD74F9CC4Q50058076-98D82ABE-4FBE-4D2C-815F-7FD5F0D40C24Q53037508-88292348-B2B8-4553-A1B2-AFCA543FCB9CQ54668276-539EF53D-7FEE-4E65-8B4D-962CCAB5FBA5Q74085412-32A5229D-3355-4993-901F-7D45A7670963Q77788947-17D0D6AF-553C-41C5-A989-4E059B4FAF19Q79314717-A24BBC1A-0A7A-442C-92C4-30D6EEA5F098Q80697148-003FAA55-325C-47C6-8A75-397A99317138Q80937287-C5BC164E-CB5E-40F9-8D42-82A5CD577E09Q81041303-3BA3F9A7-B201-4B80-BB5B-4022A49E076DQ82321077-621DEC50-DC4E-42CF-B53E-C4E33E0BF191Q82733628-96DBEA68-318A-4607-8335-8DE2A83F4111Q82887275-75631E00-DFDD-4827-B280-6CAE14551C0FQ84364235-FAE31A45-6D28-489A-BDB2-7FC7C93CCB46Q84540402-FD8BE89B-03CB-4BB7-BF40-265675EDCBC3
P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Antonino Lauria
@ast
Antonino Lauria
@en
Antonino Lauria
@es
Antonino Lauria
@nl
Antonino Lauria
@sl
type
label
Antonino Lauria
@ast
Antonino Lauria
@en
Antonino Lauria
@es
Antonino Lauria
@nl
Antonino Lauria
@sl
prefLabel
Antonino Lauria
@ast
Antonino Lauria
@en
Antonino Lauria
@es
Antonino Lauria
@nl
Antonino Lauria
@sl
P1053
I-3412-2013
P106
P1153
7003512685
P21
P2456
P31
P3829
P496
0000-0002-5116-6815