The lysine demethylase, KDM4B, is a key molecule in androgen receptor signalling and turnover.
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KDM4B/JMJD2B is a p53 target gene that modulates the amplitude of p53 response after DNA damage.The histone demethylase KDM4B regulates peritoneal seeding of ovarian cancer.Exploiting Epigenetic Alterations in Prostate Cancer.KDM4B as a target for prostate cancer: structural analysis and selective inhibition by a novel inhibitor.Androgen receptor and histone lysine demethylases in ovine placenta.KDM4/JMJD2 Histone Demethylase Inhibitors Block Prostate Tumor Growth by Suppressing the Expression of AR and BMYB-Regulated Genes.Androgen receptor regulation by histone methyltransferase Suppressor of variegation 3-9 homolog 2 and Melanoma antigen-A11.KDM4A, KDM4B and KDM4C in non-small cell lung cancer.KDM4B and KDM4A promote endometrial cancer progression by regulating androgen receptor, c-myc, and p27kip1Divergent Binding and Transactivation by Two Related Steroid Receptors at the Same Response Element.Posttranslational modification of the androgen receptor in prostate cancer.Drosophila Kdm4 demethylases in histone H3 lysine 9 demethylation and ecdysteroid signaling.LSD1 engages a corepressor complex for the activation of the estrogen receptor α by estrogen and cAMPKDM4B plays an important role in mitochondrial apoptosis by upregulating HAX1 expression in colorectal cancer.Epigenomic Regulation of Androgen Receptor Signaling: Potential Role in Prostate Cancer Therapy.Histone lysine demethylase (KDM) subfamily 4: structures, functions and therapeutic potential.The roles of Jumonji-type oxygenases in human disease.Epigenetic modifications in prostate cancer.Ubiquitin-specific protease 12 interacting partners Uaf-1 and WDR20 are potential therapeutic targets in prostate cancer.The deep end of the metabolite pool: influences on epigenetic regulatory mechanisms in cancer.Androgen receptor epigenetics.Inhibitors of Protein Methyltransferases and Demethylases.Marked for death: targeting epigenetic changes in cancer.JARID1B modulates lung cancer cell proliferation and invasion by regulating p53 expression.miR-491-5p functions as a tumor suppressor by targeting JMJD2B in ERα-positive breast cancer.KDM4C (GASC1) lysine demethylase is associated with mitotic chromatin and regulates chromosome segregation during mitosis.Deubiquitinating enzyme Usp12 is a novel co-activator of the androgen receptor.Enhancement of Proliferation and Invasion of Gastric Cancer Cell by KDM5C Via Decrease in p53 Expression.Silencing the epigenetic silencer KDM4A for TRAIL and DR5 simultaneous induction and antitumor therapy.Hypoxia and Hormone-Mediated Pathways Converge at the Histone Demethylase KDM4B in Cancer.Human ex vivo prostate tissue model system identifies ING3 as an oncoprotein.The long noncoding RNA landscape of neuroendocrine prostate cancer and its clinical implications.Epigenetic Regulation in Prostate Cancer Progression.ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancersEstrogen-responsive MYB gene expressionA network of epigenomic and transcriptional cooperation encompassing an epigenomic master regulator in cancer.Small molecule KDM4s inhibitors as anti-cancer agents.
P2860
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P2860
The lysine demethylase, KDM4B, is a key molecule in androgen receptor signalling and turnover.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
The lysine demethylase, KDM4B, ...... eptor signalling and turnover.
@en
The lysine demethylase, KDM4B, ...... eptor signalling and turnover.
@nl
type
label
The lysine demethylase, KDM4B, ...... eptor signalling and turnover.
@en
The lysine demethylase, KDM4B, ...... eptor signalling and turnover.
@nl
prefLabel
The lysine demethylase, KDM4B, ...... eptor signalling and turnover.
@en
The lysine demethylase, KDM4B, ...... eptor signalling and turnover.
@nl
P2093
P2860
P356
P1476
The lysine demethylase, KDM4B, ...... ceptor signalling and turnover
@en
P2093
Alejandra Mantilla
Claudia Ryan-Munden
Craig N Robson
Daniel O'Neill
Dhuha Alkharaif
Dominic Jones
Kanagasabai Sahadevan
Kelly Coffey
Luke Gaughan
Lynsey Rogerson
P2860
P304
P356
10.1093/NAR/GKT106
P407
P577
2013-02-21T00:00:00Z