Vinculin regulates the recruitment and release of core focal adhesion proteins in a force-dependent manner
about
Adhesion protein networks reveal functions proximal and distal to cell-matrix contactsMechanosensitive components of integrin adhesions: Role of vinculinIntegrin cytoplasmic tail interactionsMechanobiology of myofibroblast adhesion in fibrotic cardiac diseaseCadherin-11 localizes to focal adhesions and promotes cell-substrate adhesionSubstrate engagement of integrins α5β1 and αvβ3 is necessary, but not sufficient, for high directional persistence in migration on fibronectinVinculin controls talin engagement with the actomyosin machinery.The integrin adhesome network at a glanceExtracellular rigidity sensing by talin isoform-specific mechanical linkagesAll Subdomains of the Talin Rod Are Mechanically Vulnerable and May Contribute To Cellular MechanosensingIntegrin-associated complexes form hierarchically with variable stoichiometry in nascent adhesionsA plastic relationship between vinculin-mediated tension and adhesion complex area defines adhesion size and lifetime.Identification of an actin binding surface on vinculin that mediates mechanical cell and focal adhesion properties.Vinculin-actin interaction couples actin retrograde flow to focal adhesions, but is dispensable for focal adhesion growth.Actomyosin-dependent formation of the mechanosensitive talin-vinculin complex reinforces actin anchoring.Coordination between Intra- and Extracellular Forces Regulates Focal Adhesion Dynamics.Mechanical stability of talin rod controls cell migration and substrate sensing.Vinculin in cell-cell and cell-matrix adhesions.Talins and kindlins: partners in integrin-mediated adhesion.Force engages vinculin and promotes tumor progression by enhancing PI3K activation of phosphatidylinositol (3,4,5)-triphosphate.Microtubule-dependent modulation of adhesion complex composition.In vitro and in vivo evaluations of nano-hydroxyapatite/polyamide 66/glass fibre (n-HA/PA66/GF) as a novel bioactive bone screw.Loss of vinculin and membrane-bound β-catenin promotes metastasis and predicts poor prognosis in colorectal cancerSpecific dephosphorylation at tyr-554 of git1 by ptprz promotes its association with paxillin and hic-5.Cytoskeletal to Nuclear Strain Transfer Regulates YAP Signaling in Mesenchymal Stem Cells.Molecular mechanism of vinculin activation and nanoscale spatial organization in focal adhesions.Vinculin is required for cell polarization, migration, and extracellular matrix remodeling in 3D collagen.Physics of active jamming during collective cellular motion in a monolayerThe Structural Basis of Actin Organization by Vinculin and MetavinculinThree-dimensional spherical spatial boundary conditions differentially regulate osteogenic differentiation of mesenchymal stromal cellsDynamic Regulation of α-Actinin's Calponin Homology Domains on F-ActinDual role of vinculin in barrier-disruptive and barrier-enhancing endothelial cell responsesVinculin Regulates Directionality and Cell Polarity in 2D, 3D Matrix and 3D Microtrack Migration.LD Motif Recognition by Talin: Structure of the Talin-DLC1 ComplexFocal adhesion kinase is required for actin polymerization and remodeling of the cytoskeleton during sperm capacitationMatrix mechanics controls FHL2 movement to the nucleus to activate p21 expression.CAS directly interacts with vinculin to control mechanosensing and focal adhesion dynamics.Drosophila vinculin is more harmful when hyperactive than absent, and can circumvent integrin to form adhesion complexes.Mechanical activation of vinculin binding to talin locks talin in an unfolded conformation.Vinculin, cell mechanics and tumour cell invasion.
P2860
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P2860
Vinculin regulates the recruitment and release of core focal adhesion proteins in a force-dependent manner
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Vinculin regulates the recruit ...... ns in a force-dependent manner
@en
Vinculin regulates the recruit ...... s in a force-dependent manner.
@nl
type
label
Vinculin regulates the recruit ...... ns in a force-dependent manner
@en
Vinculin regulates the recruit ...... s in a force-dependent manner.
@nl
prefLabel
Vinculin regulates the recruit ...... ns in a force-dependent manner
@en
Vinculin regulates the recruit ...... s in a force-dependent manner.
@nl
P2093
P2860
P50
P1433
P1476
Vinculin regulates the recruit ...... ns in a force-dependent manner
@en
P2093
Alexandra M Greiner
Alicja Nazgiewicz
Joachim Spatz
Nadja Nijenhuis
Ralf Kemkemer
Ricky Tsang
P2860
P304
P356
10.1016/J.CUB.2013.01.009
P407
P577
2013-01-31T00:00:00Z