HIF-1α activation mediates resistance to anti-angiogenic therapy in neuroblastoma xenografts. - Wikidata - awgldk - TriplyDB

HIF-1α activation mediates resistance to anti-angiogenic therapy in neuroblastoma xenografts.

HIF-1α activation mediates resistance to anti-angiogenic therapy in neuroblastoma xenografts.

http://www.wikidata.org/entity/Q39208364

about

Metabolic and hypoxic adaptation to anti-angiogenic therapy: a target for induced essentiality ROS homeostasis and metabolism: a critical liaison for cancer therapy Targeting carbonic anhydrase IX improves the anti-cancer efficacy of mTOR inhibitors Combination therapy in combating cancer.Molecular and functional evaluation of a novel HIF inhibitor, benzopyranyl 1,2,3-triazole compound.Endoplasmic reticulum (ER) stress and hypoxia response pathways interact to potentiate hypoxia-inducible factor 1 (HIF-1) transcriptional activity on targets like vascular endothelial growth factor (VEGF)The potential role of HIF on tumour progression and dissemination.Autophagy, a double-edged sword in anti-angiogenesis therapy.Fine-Tuning Tumor Endothelial Cells to Selectively Kill Cancer.Inhibition of hypoxia inducible factors combined with all-trans retinoic acid treatment enhances glial transdifferentiation of neuroblastoma cells.Tumor dynamics in response to antiangiogenic therapy with oral metronomic topotecan and pazopanib in neuroblastoma xenografts.Metabolic alterations underlying Bevacizumab therapy in glioblastoma cells.Thrombospondin-targeting TAX2 peptide impairs tumor growth in preclinical mouse models of childhood neuroblastoma.3D Printed porous polyamide macrocapsule combined with alginate microcapsules for safer cell-based therapies.

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P2860

HIF-1α activation mediates resistance to anti-angiogenic therapy in neuroblastoma xenografts.

http://www.wikidata.org/entity/Q39208364

description

2013 nî lūn-bûn

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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2013年论文

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2013年论文

@zh-cn

name

HIF-1α activation mediates res ...... y in neuroblastoma xenografts.

@en

HIF-1α activation mediates res ...... y in neuroblastoma xenografts.

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type

label

HIF-1α activation mediates res ...... y in neuroblastoma xenografts.

@en

HIF-1α activation mediates res ...... y in neuroblastoma xenografts.

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prefLabel

HIF-1α activation mediates res ...... y in neuroblastoma xenografts.

@en

HIF-1α activation mediates res ...... y in neuroblastoma xenografts.

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P356

J.JPEDSURG.2012.10.016

P1433

Journal of Pediatric Surgery

P1476

HIF-1α activation mediates res ...... y in neuroblastoma xenografts.

@en

P2093

Andrew M Davidoff

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Catherine Y Ng

http://www.w3.org/2001/XMLSchema#string

Christopher Morton

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Joseph Hartwich

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W Shannon Orr

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Yunyu Spence

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P2860

Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics

Vascular endothelial growth factor blockade rapidly elicits alternative proangiogenic pathways in neuroblastoma

Increased antitumor activity of bevacizumab in combination with hypoxia inducible factor-1 inhibition.

HIF-1alpha modulates energy metabolism in cancer cells by inducing over-expression of specific glycolytic isoforms.

Tumor and stromal pathways mediating refractoriness/resistance to anti-angiogenic therapies.

Topotecan inhibits vascular endothelial growth factor production and angiogenic activity induced by hypoxia in human neuroblastoma by targeting hypoxia-inducible factor-1alpha and -2alpha.

Initial testing (stage 1) of sunitinib by the pediatric preclinical testing program.

Bevacizumab-induced transient remodeling of the vasculature in neuroblastoma xenografts results in improved delivery and efficacy of systemically administered chemotherapy.

Multiple receptor tyrosine kinases regulate HIF-1alpha and HIF-2alpha in normoxia and hypoxia in neuroblastoma: implications for antiangiogenic mechanisms of multikinase inhibitors.

Distinct response of experimental neuroblastoma to combination antiangiogenic strategies.

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