Atypical protein kinase C phosphorylates Par6 and facilitates transforming growth factor β-induced epithelial-to-mesenchymal transition
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Update in lung cancer and mesothelioma 2012Mechanisms of TGFβ-Induced Epithelial-Mesenchymal TransitionGenes Regulating Epithelial Polarity Are Critical Suppressors of Esophageal OncogenesisRhoGTPase signalling at epithelial tight junctions: Bridging the GAP between polarity and cancerAsymmetric cell division of stem and progenitor cells during homeostasis and cancerExpression of polarity genes in human cancer.A Drosophila Model of HPV E6-Induced Malignancy Reveals Essential Roles for Magi and the Insulin ReceptormicroRNA-214 promotes epithelial-mesenchymal transition and metastasis in lung adenocarcinoma by targeting the suppressor-of-fused protein (Sufu)Protein kinase C, focal adhesions and the regulation of cell migration.The aPKCι blocking agent ATM negatively regulates EMT and invasion of hepatocellular carcinoma.14-3-3ζ and aPKC-ι synergistically facilitate epithelial-mesenchymal transition of cholangiocarcinoma via GSK-3β/Snail signaling pathway.Shp2 Plays a Critical Role in IL-6-Induced EMT in Breast Cancer Cells.Endocytic turnover of Rab8 controls cell polarization.Atypical protein kinase Cι as a human oncogene and therapeutic target.Suppression of CIP4/Par6 attenuates TGF-β1-induced epithelial-mesenchymal transition in NRK-52E cells.TGFβ-induced phosphorylation of Par6 promotes migration and invasion in prostate cancer cellsTranscription factor glioma-associated oncogene homolog 1 is required for transforming growth factor-β1-induced epithelial-mesenchymal transition of non-small cell lung cancer cells.Secreted products of macrophages exposed to calcium oxalate crystals induce epithelial mesenchymal transition of renal tubular cells via RhoA-dependent TGF-β1 pathway.Roles of partitioning-defective protein 6 (Par6) and its complexes in the proliferation, migration and invasion of cancer cells.Par6 is phosphorylated by aPKC to facilitate EMT.Two novel atypical PKC inhibitors; ACPD and DNDA effectively mitigate cell proliferation and epithelial to mesenchymal transition of metastatic melanoma while inducing apoptosis.aPKC-ι/P-Sp1/Snail signaling induces epithelial-mesenchymal transition and immunosuppression in cholangiocarcinoma.aPKC: the Kinase that Phosphorylates Cell Polarity.ALDH1A3 upregulation and spontaneous metastasis formation is associated with acquired chemoresistance in colorectal cancer cells
P2860
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P2860
Atypical protein kinase C phosphorylates Par6 and facilitates transforming growth factor β-induced epithelial-to-mesenchymal transition
description
2012 nî lūn-bûn
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2012年の論文
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2012年論文
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name
Atypical protein kinase C phos ...... lial-to-mesenchymal transition
@en
Atypical protein kinase C phos ...... ial-to-mesenchymal transition.
@nl
type
label
Atypical protein kinase C phos ...... lial-to-mesenchymal transition
@en
Atypical protein kinase C phos ...... ial-to-mesenchymal transition.
@nl
prefLabel
Atypical protein kinase C phos ...... lial-to-mesenchymal transition
@en
Atypical protein kinase C phos ...... ial-to-mesenchymal transition.
@nl
P2093
P2860
P356
P1476
Atypical protein kinase C phos ...... lial-to-mesenchymal transition
@en
P2093
Adrian Gunaratne
Boun L Thai
Gianni M Di Guglielmo
P2860
P304
P356
10.1128/MCB.00837-12
P407
P577
2012-12-17T00:00:00Z