Phase I study of the cytotoxic agent N-[2-(dimethylamino)ethyl]acridine-4-carboxamide.
about
A novel form of intercalation involving four DNA duplexes in an acridine-4-carboxamide complex of d(CGTACG)(2)Crystal structure of 9-amino-N-[2-(4-morpholinyl)ethyl]-4-acridinecarboxamide bound to d(CGTACG)2: implications for structure-activity relationships of acridinecarboxamide topoisomerase poisons.The solution structure of bis(phenazine-1-carboxamide)-DNA complexes: MLN 944 binding corrected and extendedSelective cellular uptake and retention of SN 28049, a new DNA-binding topoisomerase II-directed antitumor agent.Unusual intercalation of acridin-9-ylthiourea into the 5'-GA/TC DNA base step from the minor groove: implications for the covalent DNA adduct profile of a novel platinum-intercalator conjugate.The role of topoisomerases and RNA transcription in the action of the antitumour benzonaphthyridine derivative SN 28049.Dual inhibition of topoisomerases I and IIα by ruthenium(II) complexes containing asymmetric tridentate ligands.
P2860
Q27627776-C2EE7690-9F74-4247-9DD2-58E15744A695Q27637488-5E258535-2DF7-4C09-9099-9DA56CCD8C5BQ27690656-41F6086C-26B7-4B29-BACC-80A5BED878E6Q35163699-4FEF6D0A-6B1C-416B-B7F9-2D5999BB8D91Q38352682-71A3DF31-C3BD-4934-95A9-BB23727F7F7AQ40028369-1FDEFCD1-368A-4784-97BC-260BD5433E76Q53414064-C51EC0EC-73E1-46F0-AD48-7AF87FCB0689
P2860
Phase I study of the cytotoxic agent N-[2-(dimethylamino)ethyl]acridine-4-carboxamide.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Phase I study of the cytotoxic agent N-[2-
@nl
Phase I study of the cytotoxic agent N-[2-(dimethylamino)ethyl]acridine-4-carboxamide.
@en
type
label
Phase I study of the cytotoxic agent N-[2-
@nl
Phase I study of the cytotoxic agent N-[2-(dimethylamino)ethyl]acridine-4-carboxamide.
@en
prefLabel
Phase I study of the cytotoxic agent N-[2-
@nl
Phase I study of the cytotoxic agent N-[2-(dimethylamino)ethyl]acridine-4-carboxamide.
@en
P2093
P356
P1476
Phase I study of the cytotoxic agent N-[2-(dimethylamino)ethyl]acridine-4-carboxamide.
@en
P2093
Baguley BC
McCrystal MR
Thompson PI
P2888
P356
10.1007/S002800050942
P577
1999-01-01T00:00:00Z