Imatinib and Nilotinib inhibit Bcr-Abl-induced ROS through targeted degradation of the NADPH oxidase subunit p22phox.
about
A NOX2/Egr-1/Fyn pathway delineates new targets for TKI-resistant malignanciesTargeting the therapeutic effects of exercise on redox-sensitive mechanisms in the vascular endothelium during tumor progressionROS signalling, NADPH oxidases and cancer.NADPH oxidase-generated hydrogen peroxide induces DNA damage in mutant FLT3-expressing leukemia cells.Chaetocin antileukemia activity against chronic myelogenous leukemia cells is potentiated by bone marrow stromal factors and overcomes innate imatinib resistance.Cell-penetrating fusion peptides OD1 and OD2 interact with Bcr-Abl and influence the growth and apoptosis of K562 cells.Alterations in the Reactive Oxygen Species in Peripheral Blood of Chronic Myeloid Leukaemia Patients from Northern India.Nilotinib interferes with the signalling pathways implicated in acetaminophen hepatotoxicity.Genomic instability is a principle pathologic feature of FLT3 ITD kinase activity in acute myeloid leukemia leading to clonal evolution and disease progression.Nuclear membrane-localised NOX4D generates pro-survival ROS in FLT3-ITD-expressing AML.
P2860
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P2860
Imatinib and Nilotinib inhibit Bcr-Abl-induced ROS through targeted degradation of the NADPH oxidase subunit p22phox.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Imatinib and Nilotinib inhibit ...... NADPH oxidase subunit p22phox.
@en
Imatinib and Nilotinib inhibit ...... NADPH oxidase subunit p22phox.
@nl
type
label
Imatinib and Nilotinib inhibit ...... NADPH oxidase subunit p22phox.
@en
Imatinib and Nilotinib inhibit ...... NADPH oxidase subunit p22phox.
@nl
prefLabel
Imatinib and Nilotinib inhibit ...... NADPH oxidase subunit p22phox.
@en
Imatinib and Nilotinib inhibit ...... NADPH oxidase subunit p22phox.
@nl
P1433
P1476
Imatinib and Nilotinib inhibit ...... NADPH oxidase subunit p22phox
@en
P2093
William D Landry
P304
P356
10.1016/J.LEUKRES.2012.11.003
P577
2012-12-03T00:00:00Z