Telomerase directly regulates NF-κB-dependent transcription.
about
Telomerase reverse transcriptase regulates microRNAsTranscription Regulation of the Human Telomerase Reverse Transcriptase (hTERT) GeneRoles of telomeres and telomerase in cancer, and advances in telomerase-targeted therapiesTelomere and Telomerase Therapeutics in CancerReactivation of telomerase in cancerTERT promoter mutations in thyroid cancerImplications of telomere-independent activities of telomerase reverse transcriptase in human cancerAberrant nuclear factor-kappa B activity in acute myeloid leukemia: from molecular pathogenesis to therapeutic targetTherapeutic targeting of replicative immortalityTERT promoter mutations and polymorphisms as prognostic factors in primary glioblastomaTelomeres and telomerase in head and neck squamous cell carcinoma: from pathogenesis to clinical implications.HPV16 E7 protein and hTERT proteins defective for telomere maintenance cooperate to immortalize human keratinocytesEfficient DNA binding of NF-κB requires the chaperone-like function of NPM1.hTERT promotes gastric intestinal metaplasia by upregulating CDX2 via NF-κB signaling pathway.Rho protein GTPases and their interactions with NFκB: crossroads of inflammation and matrix biologyChronic inflammation induces telomere dysfunction and accelerates ageing in mice.The use of transformed IMR90 cell model to identify the potential extra-telomeric effects of hTERT in cell migration and DNA damage responseDEAD-box helicase DP103 defines metastatic potential of human breast cancers.Telomerase reverse transcriptase in the regulation of gene expression.Negative regulation of signal transducer and activator of transcription-3 signalling cascade by lupeol inhibits growth and induces apoptosis in hepatocellular carcinoma cells.The multifaceted role of curcumin in cancer prevention and treatment.Attenuation of lysyl oxidase and collagen gene expression in keratoconus patient corneal epithelium corresponds to disease severity.TERT promoter mutations are associated with distant metastases in upper tract urothelial carcinomas and serve as urinary biomarkers detected by a sensitive castPCRRe-expression of HPV16 E2 in SiHa (human cervical cancer) cells potentiates NF-κB activation induced by TNF-α concurrently increasing senescence and survivalReciprocal activation between IL-6/STAT3 and NOX4/Akt signalings promotes proliferation and survival of non-small cell lung cancer cells.Association of TERT Polymorphisms with Clinical Outcome of Non-Small Cell Lung Cancer Patients.Telomerase regulates MYC-driven oncogenesis independent of its reverse transcriptase activity.The DNA methylation inhibitor induces telomere dysfunction and apoptosis of leukemia cells that is attenuated by telomerase over-expression.Garcinol sensitizes human head and neck carcinoma to cisplatin in a xenograft mouse model despite downregulation of proliferative biomarkers.Association between TERT promoter polymorphisms and acute myeloid leukemia risk and prognosis.Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation.Telomere Length, TERT, and miRNA ExpressionGenomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition.miR-346 and miR-138 competitively regulate hTERT in GRSF1- and AGO2-dependent manners, respectively.Association of telomerase reverse transcriptase promoter mutations with clinicopathological features and prognosis of thyroid cancer: a meta-analysis.Cross talk between EBV and telomerase: the role of TERT and NOTCH2 in the switch of latent/lytic cycle of the virusTrefoil factor 1 expression suppresses Helicobacter pylori-induced inflammation in gastric carcinogenesis.Gastrointestinal cancer cells treatment with bevacizumab activates a VEGF autoregulatory mechanism involving telomerase catalytic subunit hTERT via PI3K-AKT, HIF-1α and VEGF receptorsTelomerase reverse transcriptase acts in a feedback loop with NF-κB pathway to regulate macrophage polarization in alcoholic liver disease.Bortezomib-mediated down-regulation of telomerase and disruption of telomere homeostasis contributes to apoptosis of malignant cells.
P2860
Q24313154-DE7A0A60-B34D-4535-B1AF-153AD73AFD19Q26739925-E3CAD46D-1321-4843-B95A-CE25DFCCAD91Q26744271-FF7DF306-98F3-4CFD-8C94-2AB4DDA32A39Q26744808-F11D0B99-4DC4-4522-8B5E-8E2CEF44C9CEQ26769014-0AC2C491-8669-4E1B-87F1-EB153140E2ACQ26770808-2E4B5DA4-4803-43FD-ADF0-2457847A6D76Q26825812-4A2DFBFB-AB0D-4465-8F6F-18259BCC794CQ26995561-94CE1F28-D200-432F-BE65-97451EAF11AAQ27027457-5857AC92-EF35-4490-A1E2-835850D3EB46Q28390726-E8707F09-D1A0-45A6-A3F6-3351D9D0A2BFQ30248577-774E4C9D-01B9-4D23-AD84-B116287F5670Q31115332-4631F75F-3392-4577-8891-2ED67D910402Q33580398-B63A6705-D651-4FDC-AAB2-2E9F67A73401Q33688891-24F6DA80-7534-4DC8-9712-5A395C9E5D6CQ33802112-F71422C4-3FBF-455D-94C4-47C9297AE752Q33877362-35F78773-9B1D-4326-A944-7C0590C22B94Q34021399-5E2B3616-83F0-4201-8D75-2EE8C5CB9F71Q34117601-02CEC190-ED12-4D2E-BAC3-E4D24B2FF131Q34179834-3D1B294B-EF19-43DB-BE3A-534C36D5E182Q34283730-801511D3-EFE3-433B-A56B-06C7C914E6EAQ34667865-6DDA4023-0EC9-4B4C-AB9F-015AD9E46C2CQ34994089-AB2C108C-9DA6-4158-9F02-3A00E82798D5Q35068013-5FB60796-374A-4CD2-B039-336D1EB132D7Q35120785-034E0982-D1DB-4499-B89B-9282EB0FD112Q35176004-12B2FB9D-79E4-4EFC-AF63-30808BA191FDQ35644577-2556DA0C-D7CB-4DB3-9842-C1F580BED93BQ35720003-93574628-0670-4F8C-AE24-BC7F48598C93Q35741571-65AC86AA-79A0-4419-9ABC-DCFEB7519AAFQ35741628-2B95BDC4-94F5-42E4-A735-DFDBF1CD5164Q35753087-ED37B369-25D2-4327-9A30-3260BC7F13D8Q35820032-73F9CB4C-BE21-4BE4-9028-304BF1984016Q36132829-A50412C0-DD7C-49D7-AA4D-0728E8774541Q36144711-DFDBA9AF-2D83-4EFC-AE75-E4E5431FD0F9Q36216239-2451B60C-CD8B-4F7F-8D4F-43A3F703BD03Q36221232-89150E2C-02ED-414E-BD43-6EE6B7D747E8Q36346985-5217A349-0117-43A1-8876-0A2CDFB662BCQ36348877-C69D7174-DC11-4C7C-864F-EBFB0CEC974DQ36395933-97EA04A0-9CF0-43A6-973A-D9F6C00DF051Q36423119-12F9F1C7-DE09-4976-AB58-2B4B2F3AC3F6Q36545969-2CCA2380-789A-4E5B-A7C5-59DBA73B4FD5
P2860
Telomerase directly regulates NF-κB-dependent transcription.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Telomerase directly regulates NF-κB-dependent transcription.
@en
Telomerase directly regulates NF-κB-dependent transcription.
@nl
type
label
Telomerase directly regulates NF-κB-dependent transcription.
@en
Telomerase directly regulates NF-κB-dependent transcription.
@nl
prefLabel
Telomerase directly regulates NF-κB-dependent transcription.
@en
Telomerase directly regulates NF-κB-dependent transcription.
@nl
P2093
P2860
P50
P356
P1433
P1476
Telomerase directly regulates NF-κB-dependent transcription
@en
P2093
Edison Liu
Ekta Khattar
Eun Myong Shin
Guoliang Li
Jianbiao Zhou
Shi Chi Leow
Ting Dong Yan
Vinay Tergaonkar
P2860
P2888
P304
P356
10.1038/NCB2621
P577
2012-11-18T00:00:00Z