An integrated genomic screen identifies LDHB as an essential gene for triple-negative breast cancer.
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Robust prediction of anti-cancer drug sensitivity and sensitivity-specific biomarkerGeneralized portrait of cancer metabolic pathways inferred from a list of genes overexpressed in cancerThe latest progress in research on triple negative breast cancer (TNBC): risk factors, possible therapeutic targets and prognostic markersQuinoline 3-sulfonamides inhibit lactate dehydrogenase A and reverse aerobic glycolysis in cancer cells.The basal epithelial marker P-cadherin associates with breast cancer cell populations harboring a glycolytic and acid-resistant phenotype.Role of aerobic glycolysis in genetically engineered mouse models of cancer.Integrating transcriptomics and proteomics to show that tanshinone IIA suppresses cell growth by blocking glucose metabolism in gastric cancer cells.Inhibition of lactate dehydrogenase activity as an approach to cancer therapy.Inhibition of the Warburg effect with a natural compound reveals a novel measurement for determining the metastatic potential of breast cancers.A novel class of mitochondria-targeted soft electrophiles modifies mitochondrial proteins and inhibits mitochondrial metabolism in breast cancer cells through redox mechanisms.Lactate dehydrogenase B is associated with the response to neoadjuvant chemotherapy in oral squamous cell carcinomaMetabolic Signatures of Human Breast Cancer.Prognostic Significance of Promoter DNA Hypermethylation of cysteine dioxygenase 1 (CDO1) Gene in Primary Breast CancerTherapeutic Targeting of the Warburg Effect in Pancreatic Cancer Relies on an Absence of p53 Function.Low Expression of LDHB Correlates With Unfavorable Survival in Hepatocellular Carcinoma: Strobe-Compliant Article.Genomic pathways modulated by Twist in breast cancer.HIF isoforms have divergent effects on invasion, metastasis, metabolism and formation of lipid droplets.Epigenetic regulation of ZEB1-RAB25/ESRP1 axis plays a critical role in phenylbutyrate treatment-resistant breast cancer.Lactate dehydrogenase B: a metabolic marker of response to neoadjuvant chemotherapy in breast cancer.A genome-wide siRNA screen identifies proteasome addiction as a vulnerability of basal-like triple-negative breast cancer cells.Radiation-induced gene signature predicts pathologic complete response to neoadjuvant chemotherapy in breast cancer patientsCited2, a transcriptional modulator protein, regulates metabolism in murine embryonic stem cells.LDHB may be a significant predictor of poor prognosis in osteosarcoma.Cancer cell metabolism and the modulating effects of nitric oxide.Stable shRNA Silencing of Lactate Dehydrogenase A (LDHA) in Human MDA-MB-231 Breast Cancer Cells Fails to Alter Lactic Acid Production, Glycolytic Activity, ATP or Survival.MCT1 in Invasive Ductal Carcinoma: Monocarboxylate Metabolism and Aggressive Breast Cancer.Patterns of differentially expressed genes in oral mucosal lesions visualised under autofluorescence (VELscope(™) ).Detection and screening of small molecule agents for overcoming Sorafenib resistance of hepatocellular carcinoma: a bioinformatics studyReprogramming of glucose, fatty acid and amino acid metabolism for cancer progression.Metabolic profiling of triple-negative breast cancer cells reveals metabolic vulnerabilities.Proteomic analysis of the cytotoxic effects induced by the organogold(III) complex Aubipyc in cisplatin-resistant A2780 ovarian cancer cells: further evidence for the glycolytic pathway implication.Suppressed expression of LDHB promotes pancreatic cancer progression via inducing glycolytic phenotype.The drs tumor suppressor regulates glucose metabolism via lactate dehydrogenase-B.Modeling the Genetic Regulation of Cancer Metabolism: Interplay between Glycolysis and Oxidative Phosphorylation.A pilot study of an autologous tumor-derived autophagosome vaccine with docetaxel in patients with stage IV non-small cell lung cancer.Linking CREB function with altered metabolism in murine fibroblast-based model cell lines.ADHFE1 is a breast cancer oncogene and induces metabolic reprogramming.Metabolic Plasiticy in Cancers-Distinct Role of Glycolytic Enzymes GPI, LDHs or Membrane Transporters MCTs.Yeast cell-based analysis of human lactate dehydrogenase isoforms.Inhibition of stress mediated cell death by human lactate dehydrogenase B in yeast.
P2860
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P2860
An integrated genomic screen identifies LDHB as an essential gene for triple-negative breast cancer.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
An integrated genomic screen i ...... triple-negative breast cancer.
@en
An integrated genomic screen i ...... triple-negative breast cancer.
@nl
type
label
An integrated genomic screen i ...... triple-negative breast cancer.
@en
An integrated genomic screen i ...... triple-negative breast cancer.
@nl
prefLabel
An integrated genomic screen i ...... triple-negative breast cancer.
@en
An integrated genomic screen i ...... triple-negative breast cancer.
@nl
P2093
P1433
P1476
An integrated genomic screen i ...... triple-negative breast cancer
@en
P2093
Benjamin Haley
David Peterson
Elizabeth M Blackwood
Eric Torres
Georgia Hatzivassiliou
Jean-Philippe Stephan
Jiping Zha
Laura Corson
Marcia Belvin
P304
P356
10.1158/0008-5472.CAN-12-1098
P407
P50
P577
2012-11-08T00:00:00Z