Passenger Mutations Confound Interpretation of All Genetically Modified Congenic Mice. - Wikidata - awgldk - TriplyDB

Passenger Mutations Confound Interpretation of All Genetically Modified Congenic Mice.

Passenger Mutations Confound Interpretation of All Genetically Modified Congenic Mice.

http://www.wikidata.org/entity/Q39254212

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Show and tell: disclosure and data sharing in experimental pathology Emerging Functions of Natural IgM and Its Fc Receptor FCMR in Immune Homeostasis Gene Targeting Using Homologous Recombination in Embryonic Stem Cells: The Future for Behavior Genetics?Attention to Background Strain Is Essential for Metabolic Research: C57BL/6 and the International Knockout Mouse Consortium Heterogeneity of the gut microbiome in mice: guidelines for optimizing experimental design Perspectives on the role of Pannexin 1 in neural precursor cell biology NCAM1 Polysialylation: The Prion Protein's Elusive Reason for Being?Rheumatoid arthritis: identifying and characterising polymorphisms using rat models Critical Role of the Disintegrin Metalloprotease ADAM-like Decysin-1 [ADAMDEC1] for Intestinal Immunity and Inflammation BACE1 across species: a comparison of the in vivo consequences of BACE1 deletion in mice and rats FcγRIIB and autoimmunity.Next-generation mammalian genetics toward organism-level systems biology Inhibition of gelatinase B/MMP-9 does not attenuate colitis in murine models of inflammatory bowel disease.Loss of the Homeodomain Transcription Factor Prep1 Perturbs Adult Hematopoiesis in the Bone Marrow.Direct Comparison of a Natural Loss-Of-Function Single Nucleotide Polymorphism with a Targeted Deletion in the Ncf1 Gene Reveals Different Phenotypes.High-Speed Mouse Backcrossing Through the Female Germ Line.Perforin-2 is essential for intracellular defense of parenchymal cells and phagocytes against pathogenic bacteria.Prion pathogenesis is unaltered in the absence of SIRPα-mediated "don't-eat-me" signaling.Strictly co-isogenic C57BL/6J-Prnp-/- mice: A rigorous resource for prion science.Efficient analysis of mouse genome sequences reveal many nonsense variants.PrimPol prevents APOBEC/AID family mediated DNA mutagenesis Cohort Removal Induces Changes in Body Temperature, Pain Sensitivity, and Anxiety-Like Behavior.Interrogating the relevance of mitochondrial apoptosis for vertebrate development and postnatal tissue homeostasis Nlrp12 mutation causes C57BL/6J strain-specific defect in neutrophil recruitment.MMP-3 Deficiency Alleviates Endotoxin-Induced Acute Inflammation in the Posterior Eye Segment.Passenger mutations and aberrant gene expression in congenic tissue plasminogen activator-deficient mouse strains.Passenger Gene Mutations: Unwanted Guests in Genetically Modified Mice.Complete overview of protein-inactivating sequence variations in 36 sequenced mouse inbred strains.Recent developments in severe sepsis research: from bench to bedside and back.TALENs and CRISPR/Cas9 fuel genetically engineered clinically relevant Xenopus tropicalis tumor models.CHIP controls necroptosis through ubiquitylation- and lysosome-dependent degradation of RIPK3.The molecular biology of matrix metalloproteinases and tissue inhibitors of metalloproteinases in inflammatory bowel diseases.Applications and Limitations of Mouse Models for Understanding Human Atherosclerosis.Absent in Melanoma 2 proteins in SLE.RNA Sequencing of Murine Norovirus-Infected Cells Reveals Transcriptional Alteration of Genes Important to Viral Recognition and Antigen Presentation.The AIM2-like Receptors Are Dispensable for the Interferon Response to Intracellular DNA.Priming and Activation of Inflammasome by Canarypox Virus Vector ALVAC via the cGAS/IFI16-STING-Type I IFN Pathway and AIM2 Sensor.Is BOK required for apoptosis induced by endoplasmic reticulum stress?Response to Heard et al.Research data: Silver lining to irreproducibility.

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Passenger Mutations Confound Interpretation of All Genetically Modified Congenic Mice.

http://www.wikidata.org/entity/Q39254212

description

2015 nî lūn-bûn

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2015年の論文

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年學術文章

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2015年學術文章

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2015年學術文章

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name

Passenger Mutations Confound Interpretation of All Genetically Modified Congenic Mice.

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Passenger Mutations Confound Interpretation of All Genetically Modified Congenic Mice.

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type

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Passenger Mutations Confound Interpretation of All Genetically Modified Congenic Mice.

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Passenger Mutations Confound Interpretation of All Genetically Modified Congenic Mice.

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Passenger Mutations Confound Interpretation of All Genetically Modified Congenic Mice.

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Passenger Mutations Confound Interpretation of All Genetically Modified Congenic Mice.

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J.IMMUNI.2015.06.011

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Passenger Mutations Confound Interpretation of All Genetically Modified Congenic Mice

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Claude Libert

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Elien Van Wonterghem

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Inge Bruggeman

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Liesbet Martens

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Marnik Vuylsteke

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Sze Men Choi

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Valery I Shestopalov

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A conditional knockout resource for the genome-wide study of mouse gene function

The knockout mouse project

RNA-guided human genome engineering via Cas9

Multiplex genome engineering using CRISPR/Cas systems

Update of the human and mouse SERPIN gene superfamily

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

The classical pink-eyed dilution mutation affects angiogenic responsiveness

Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice

Cryopyrin activates the inflammasome in response to toxins and ATP

Non-canonical inflammasome activation targets caspase-11

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200-209

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