Inhibition of cell proliferation by a selective inhibitor of the Ca(2+)-activated Cl(-) channel, Ano1.
about
The bestrophin- and TMEM16A-associated Ca(2+)- activated Cl(–) channels in vascular smooth musclesThe Ca(2+) -activated Cl(-) channel, ANO1 (TMEM16A), is a double-edged sword in cell proliferation and tumorigenesisInhibition of ANO1/TMEM16A Chloride Channel by Idebenone and Its Cytotoxicity to Cancer Cell LinesAni9, A Novel Potent Small-Molecule ANO1 Inhibitor with Negligible Effect on ANO2Ano1, a Ca2+-activated Cl- channel, coordinates contractility in mouse intestine by Ca2+ transient coordination between interstitial cells of CajalThe Ca2+-activated Cl- channel ANO1/TMEM16A regulates primary ciliogenesisModulating Ca²⁺ signals: a common theme for TMEM16, Ist2, and TMC.Identification and characterization of a novel promoter for the human ANO1 gene regulated by the transcription factor signal transducer and activator of transcription 6 (STAT6)Anoctamin 6 regulates C2C12 myoblast proliferationANO1 (TMEM16A) in pancreatic ductal adenocarcinoma (PDAC)Inhibition of Calcium-Activated Chloride Channel ANO1/TMEM16A Suppresses Tumor Growth and Invasion in Human Lung Cancer.TMEM16A overexpression contributes to tumor invasion and poor prognosis of human gastric cancer through TGF-β signaling.New selective inhibitors of calcium-activated chloride channels - T16A(inh) -A01, CaCC(inh) -A01 and MONNA - what do they inhibit?A novel exon in the human Ca2+-activated Cl- channel Ano1 imparts greater sensitivity to intracellular Ca2.Inhibition of ANO1 by luteolin and its cytotoxicity in human prostate cancer PC-3 cellsIdentification and characterization of ANO9 in stage II and III colorectal carcinoma.Suppression of 14-3-3γ-mediated surface expression of ANO1 inhibits cancer progression of glioblastoma cells.TMEM16A alternative splicing coordination in breast cancer.Purified TMEM16A is sufficient to form Ca2+-activated Cl- channels.Activation of the Ano1 (TMEM16A) chloride channel by calcium is not mediated by calmodulin.Cell volume regulation in epithelial physiology and cancerInterstitial cells of Cajal: update on basic and clinical science.Role of anoctamins in cancer and apoptosis.Functions of volume-sensitive and calcium-activated chloride channels.TMEM16 proteins: unknown structure and confusing functions.Role of volume-regulated and calcium-activated anion channels in cell volume homeostasis, cancer and drug resistanceHomodimeric anoctamin-1, but not homodimeric anoctamin-6, is activated by calcium increases mediated by the P2Y1 and P2X7 receptors.Small molecule-facilitated degradation of ANO1 protein: a new targeting approach for anticancer therapeutics.Pharmacological characterization of TMEM16A currents9-Phenanthrol inhibits recombinant and arterial myocyte TMEM16A channels.Mechanisms underlying spontaneous constrictions of postcapillary venules in the rat stomach.Inhibition of transmembrane member 16A calcium-activated chloride channels by natural flavonoids contributes to flavonoid anticancer effects.Conditional genetic deletion of Ano1 in interstitial cells of Cajal impairs Ca2+ transients and slow waves in adult mouse small intestine.EAVK segment "c" sequence confers Ca2+-dependent changes to the kinetics of full-length human Ano1.Expression of ANO1/DOG1 is associated with shorter survival and progression of breast carcinomas.TMEM16A regulates portal vein smooth muscle cell proliferation in portal hypertension.Functional properties of submucosal venules in the rat stomach.
P2860
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P2860
Inhibition of cell proliferation by a selective inhibitor of the Ca(2+)-activated Cl(-) channel, Ano1.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Inhibition of cell proliferati ...... activated Cl(-) channel, Ano1.
@en
Inhibition of cell proliferati ...... activated Cl(-) channel, Ano1.
@nl
type
label
Inhibition of cell proliferati ...... activated Cl(-) channel, Ano1.
@en
Inhibition of cell proliferati ...... activated Cl(-) channel, Ano1.
@nl
prefLabel
Inhibition of cell proliferati ...... activated Cl(-) channel, Ano1.
@en
Inhibition of cell proliferati ...... activated Cl(-) channel, Ano1.
@nl
P2093
P2860
P1476
Inhibition of cell proliferati ...... -activated Cl(-) channel, Ano1
@en
P2093
Amelia Mazzone
Gianrico Farrugia
Peter R Strege
Seth T Eisenman
Tamas Ordog
P2860
P304
P356
10.1016/J.BBRC.2012.09.022
P407
P577
2012-09-17T00:00:00Z