The prolyl-isomerase Pin1 activates the mitochondrial death program of p53
about
Alterations in Mitochondrial and Endoplasmic Reticulum Signaling by p53 MutantsMitochondria, calcium, and tumor suppressor Fus1: At the crossroad of cancer, inflammation, and autoimmunityProlyl isomerase Pin1 in cancerAnother fork in the road--life or death decisions by the tumour suppressor p53Dynamic regulation of Pin1 expression and function during zebrafish development.Hyaluronic acid induces activation of the κ-opioid receptor.TAp73 promotes anti-senescence-anabolism not proliferation.Bioinformatics analysis of the serine and glycine pathway in cancer cellsToward a new STATe: the role of STATs in mitochondrial function.p53 at the endoplasmic reticulum regulates apoptosis in a Ca2+-dependent manner.Intravital imaging reveals p53-dependent cancer cell death induced by phototherapy via calcium signaling.Decrease of mitochondrial p53 during late apoptosis is linked to its dephosphorylation on serine 20Heat stress induced apoptosis is triggered by transcription-independent p53, Ca(2+) dyshomeostasis and the subsequent Bax mitochondrial translocation.Peptidyl Prolyl Isomerase PIN1 Directly Binds to and Stabilizes Hypoxia-Inducible Factor-1α.Dynamic Protein Interaction Networks and New Structural Paradigms in Signaling.Peritoneal expression of Matrilysin helps identify early post-operative recurrence of colorectal cancer.Pin1-Induced Proline Isomerization in Cytosolic p53 Mediates BAX Activation and Apoptosis.Grb7 Protein Stability Modulated by Pin1 in Association with Cell Cycle ProgressionMDM4/HIPK2/p53 cytoplasmic assembly uncovers coordinated repression of molecules with anti-apoptotic activity during early DNA damage responseComplete thermodynamic and kinetic characterization of the isomer-specific interaction between Pin1-WW domain and the amyloid precursor protein cytoplasmic tail phosphorylated at Thr668.Long story short: p53 mediates innate immunity.Autophosphorylation and Pin1 binding coordinate DNA damage-induced HIPK2 activation and cell death.Prolyl isomerase Pin1 and protein kinase HIPK2 cooperate to promote cortical neurogenesis by suppressing Groucho/TLE:Hes1-mediated inhibition of neuronal differentiation.Prolyl-isomerase Pin1 controls normal and cancer stem cells of the breast.Heat stress induces apoptosis through transcription-independent p53-mediated mitochondrial pathways in human umbilical vein endothelial cell.The cytoplasmic side of p53's oncosuppressive activities.ShaPINg Cell Fate Upon DNA Damage: Role of Pin1 Isomerase in DNA Damage-Induced Cell Death and Repair.Cofactor Strap regulates oxidative phosphorylation and mitochondrial p53 activity through ATP synthase.Mitochondrial death functions of p53.The Tyrosine Kinase c-Abl Promotes Homeodomain-interacting Protein Kinase 2 (HIPK2) Accumulation and Activation in Response to DNA Damage.PIN1 in breast development and cancer: a clinical perspective.DLX5, FGF8 and the Pin1 isomerase control ΔNp63α protein stability during limb development: a regulatory loop at the basis of the SHFM and EEC congenital malformations.Forecasting cell death dose-response from early signal transduction responses in vitroGenome wide analysis of Cyclophilin gene family from rice and Arabidopsis and its comparison with yeast.Pin1 is required for sustained B cell proliferation upon oncogenic activation of MycSubcellular calcium measurements in mammalian cells using jellyfish photoprotein aequorin-based probes.Targeting prolyl-isomerase Pin1 prevents mitochondrial oxidative stress and vascular dysfunction: insights in patients with diabetes.miR-663 sustains NSCLC by inhibiting mitochondrial outer membrane permeabilization (MOMP) through PUMA/BBC3 and BTG2.Notch signaling and neuronal death in stroke.Peptidyl-prolyl cis/trans isomerase Pin1 regulates withaferin A-mediated cell cycle arrest in human breast cancer cells.
P2860
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P2860
The prolyl-isomerase Pin1 activates the mitochondrial death program of p53
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
The prolyl-isomerase Pin1 activates the mitochondrial death program of p53
@en
The prolyl-isomerase Pin1 activates the mitochondrial death program of p53.
@nl
type
label
The prolyl-isomerase Pin1 activates the mitochondrial death program of p53
@en
The prolyl-isomerase Pin1 activates the mitochondrial death program of p53.
@nl
prefLabel
The prolyl-isomerase Pin1 activates the mitochondrial death program of p53
@en
The prolyl-isomerase Pin1 activates the mitochondrial death program of p53.
@nl
P2093
P2860
P50
P356
P1476
The prolyl-isomerase Pin1 activates the mitochondrial death program of p53
@en
P2093
P2860
P2888
P304
P356
10.1038/CDD.2012.112
P577
2012-08-31T00:00:00Z