Toward a novel metal-based chemotherapy against tropical diseases. 3. Synthesis and antimalarial activity in vitro and in vivo of the new gold-chloroquine complex [Au(PPh3)(CQ)]PF6.
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The therapeutic potential of metal-based antimalarial agents: implications for the mechanism of actionAntimalarial activity and mechanisms of action of two novel 4-aminoquinolines against chloroquine-resistant parasitesPreparation, physicochemical characterization and biological evaluation of cefodizime metal ion complexes.Synthesis, Antiplasmodial Activity, and β-Hematin Inhibition of Hydroxypyridone-Chloroquine HybridsBeneficial effect of aurothiomalate on murine malaria.Synthesis and antimalarial activity of metal complexes of cross-bridged tetraazamacrocyclic ligands.Ruthenium(II) arene complexes with chelating chloroquine analogue ligands: synthesis, characterization and in vitro antimalarial activity.1,2-disubstituted ferrocenyl carbohydrate chloroquine conjugates as potential antimalarial agents.{4-[(7-Chloro-4-quinol-yl)amino]-N,N-di-ethyl-penta-naminium}(triphenyl-phos-phine)gold(I) dinitrate.Metal-chloroquine derivatives as possible anti-malarial drugs: evaluation of anti-malarial activity and mode of action.Antioxidant and hepatoprotective role of gold nanoparticles against murine hepatic schistosomiasisWater Soluble Phosphane-Gold(I) Complexes. Applications as Recyclable Catalysts in a Three-component Coupling Reaction and as Antimicrobial and Anticancer Agents.Synthesis, characterization, and in vitro antimalarial and antitumor activity of new ruthenium(II) complexes of chloroquine.The tumor proteasome as a novel target for gold(III) complexes: implications for breast cancer therapyDiscovery of Antischistosomal Drug Leads Based on Tetraazamacrocyclic Derivatives and Their Metal Complexes.Applications of gold(I) alkynyl systems: a growing field to explore.Gold complexes as antimicrobial agents: an overview of different biological activities in relation to the oxidation state of the gold ion and the ligand structure.The mechanism of antimalarial action of the ruthenium(II)-chloroquine complex [RuCl(2)(CQ)] (2).Some nontoxic metal-based drugs for selected prevalent tropical pathogenic diseases.Potential cytotoxic and amoebicide activity of first row transition metal compounds with 2,9-bis-(2',5'-diazahexanyl)-1,1-phenanthroline (L1).Antimycobacterial activity of fusaric acid from a mangrove endophyte and its metal complexes.Chloroquine-containing organoruthenium complexes are fast-acting multistage antimalarial agents.Interactions of arene-Ru(II)-chloroquine complexes of known antimalarial and antitumor activity with human serum albumin (HSA) and transferrinThe mechanism of antimalarial action of [Au(CQ)(PPh(3))]PF(6): structural effects and increased drug lipophilicity enhance heme aggregation inhibition at lipid/water interfaces.Metallocene antimalarials: the continuing questSynthesis, structures and anti-malaria activity of some gold(I) phosphine complexes containing seleno- and thiosemicarbazonato ligands.The antimalarial activity of Ru-chloroquine complexes against resistant Plasmodium falciparum is related to lipophilicity, basicity, and heme aggregation inhibition ability near water/n-octanol interfaces.
P2860
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P2860
Toward a novel metal-based chemotherapy against tropical diseases. 3. Synthesis and antimalarial activity in vitro and in vivo of the new gold-chloroquine complex [Au(PPh3)(CQ)]PF6.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Toward a novel metal-based che ...... w gold-chloroquine complex [Au
@nl
Toward a novel metal-based che ...... ine complex [Au(PPh3)(CQ)]PF6.
@en
type
label
Toward a novel metal-based che ...... w gold-chloroquine complex [Au
@nl
Toward a novel metal-based che ...... ine complex [Au(PPh3)(CQ)]PF6.
@en
prefLabel
Toward a novel metal-based che ...... w gold-chloroquine complex [Au
@nl
Toward a novel metal-based che ...... ine complex [Au(PPh3)(CQ)]PF6.
@en
P2093
P921
P356
P1476
Toward a novel metal-based che ...... ine complex [Au(PPh3)(CQ)]PF6.
@en
P2093
Sánchez-Delgado RA
P304
P356
10.1021/JM9607358
P407
P577
1997-06-01T00:00:00Z