Hyperpolarized 13C lactate, pyruvate, and alanine: noninvasive biomarkers for prostate cancer detection and grading. - Wikidata - awgldk - TriplyDB

Hyperpolarized 13C lactate, pyruvate, and alanine: noninvasive biomarkers for prostate cancer detection and grading.

Hyperpolarized 13C lactate, pyruvate, and alanine: noninvasive biomarkers for prostate cancer detection and grading.

http://www.wikidata.org/entity/Q39301749

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Metabolic Imaging to Assess Treatment Response to Cytotoxic and Cytostatic Agents Potential Clinical Roles for Metabolic Imaging with Hyperpolarized [1-(13)C]Pyruvate The use of dynamic nuclear polarization (13)C-pyruvate MRS in cancer Molecular magnetic resonance imaging in cancer Hyperpolarized magnetic resonance as a sensitive detector of metabolic function Chemistry and biochemistry of 13C hyperpolarized magnetic resonance using dynamic nuclear polarization Metabolic Imaging in Prostate Cancer: Where We Are Imaging metabolic heterogeneity in cancer Magnetic resonance spectroscopy detectable metabolomic fingerprint of response to antineoplastic treatment Model free approach to kinetic analysis of real-time hyperpolarized 13C magnetic resonance spectroscopy data Use of nuclear magnetic resonance-based metabolomics to characterize the biochemical effects of naphthalene on various organs of tolerant mice Molecular imaging without radiopharmaceuticals?Hyperpolarized water as an MR imaging contrast agent: feasibility of in vivo imaging in a rat model Efficient transformation of parahydrogen spin order into heteronuclear magnetization.Parahydrogen induced polarization of 1-(13)C-phospholactate-d(2) for biomedical imaging with >30,000,000-fold NMR signal enhancement in water.High-resolution low-field molecular magnetic resonance imaging of hyperpolarized liquids.Direct quantitative 13 C-filtered 1 H magnetic resonance imaging of PEGylated biomacromolecules in vivo.Mis-estimation and bias of hyperpolarized apparent diffusion coefficient measurements due to slice profile effects.Imaging Extracellular Lactate In Vitro and In Vivo Using CEST MRI and a Paramagnetic Shift Reagent.Radial spectroscopic MRI of hyperpolarized [1-(13) C] pyruvate at 7 tesla Imaging and 'omic' methods for the molecular diagnosis of cancer.Continuous flow Overhauser dynamic nuclear polarization of water in the fringe field of a clinical magnetic resonance imaging system for authentic image contrast 3D compressed sensing for highly accelerated hyperpolarized (13)C MRSI with in vivo applications to transgenic mouse models of cancer Hyperpolarized (13)C spectroscopy and an NMR-compatible bioreactor system for the investigation of real-time cellular metabolism.Dynamic hyperpolarized carbon-13 MR metabolic imaging of nonhuman primate brain.Investigation of tumor hyperpolarized [1-13C]-pyruvate dynamics using time-resolved multiband RF excitation echo-planar MRSI.Magnetic resonance imaging of the tumor microenvironment in radiotherapy: perfusion, hypoxia, and metabolism.Magnetic resonance spectroscopy in metabolic and molecular imaging and diagnosis of cancer Magnetic resonance in the era of molecular imaging of cancer Assessment of therapeutic response and treatment planning for brain tumors using metabolic and physiological MRI.Multi-compound polarization by DNP allows simultaneous assessment of multiple enzymatic activities in vivo T(2) relaxation times of (13)C metabolites in a rat hepatocellular carcinoma model measured in vivo using (13)C-MRS of hyperpolarized [1-(13)C]pyruvate.Hyperpolarized 13C magnetic resonance metabolic imaging: application to brain tumors Is higher lactate an indicator of tumor metastatic risk? A pilot MRS study using hyperpolarized (13)C-pyruvate.Metabolic imaging of patients with prostate cancer using hyperpolarized [1-¹³C]pyruvate On-target inhibition of tumor fermentative glycolysis as visualized by hyperpolarized pyruvate.Hyperpolarized singlet lifetimes of pyruvate in human blood and in the mouse.Analysis of cancer metabolism by imaging hyperpolarized nuclei: prospects for translation to clinical research.Probing early tumor response to radiation therapy using hyperpolarized [1-¹³C]pyruvate in MDA-MB-231 xenografts.In vivo (1) H MR spectroscopic imaging of aggressive prostate cancer: can we detect lactate?

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P2860

Hyperpolarized 13C lactate, pyruvate, and alanine: noninvasive biomarkers for prostate cancer detection and grading.

http://www.wikidata.org/entity/Q39301749

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年學術文章

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2008年學術文章

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name

Hyperpolarized 13C lactate, py ...... cancer detection and grading.

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Hyperpolarized 13C lactate, py ...... cancer detection and grading.

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Hyperpolarized 13C lactate, py ...... cancer detection and grading.

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Hyperpolarized 13C lactate, py ...... cancer detection and grading.

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Hyperpolarized 13C lactate, py ...... cancer detection and grading.

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Hyperpolarized 13C lactate, py ...... cancer detection and grading.

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Cancer Research

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Hyperpolarized 13C lactate, py ...... cancer detection and grading.

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Albert P Chen

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Charles H Cunningham

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Daniel B Vigneron

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James Tropp

http://www.w3.org/2001/XMLSchema#string

John Kurhanewicz

http://www.w3.org/2001/XMLSchema#string

Mark J Albers

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Matt L Zierhut

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Ralph E Hurd

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Robert Bok

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Sarah J Nelson

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P2860

Human monocarboxylate transporter 2 (MCT2) is a high affinity pyruvate transporter

Increase in signal-to-noise ratio of > 10,000 times in liquid-state NMR

On the Origin of Cancer Cells

Why do cancers have high aerobic glycolysis?

Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

Correlation of proton MR spectroscopic imaging with gleason score based on step-section pathologic analysis after radical prostatectomy.

High spatial resolution and speed in MRSI.

The prostate: MR imaging and spectroscopy. Present and future.

Detecting tumor response to treatment using hyperpolarized 13C magnetic resonance imaging and spectroscopy.

The pathways of glutamate and glutamine oxidation by tumor cell mitochondria. Role of mitochondrial NAD(P)+-dependent malic enzyme.

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8607-8615

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