Seasonal carriage of pfcrt and pfmdr1 alleles in Gambian Plasmodium falciparum imply reduced fitness of chloroquine-resistant parasites.
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Intermittent preventive antimalarial treatment for children with anaemiaAntimalarial Drug Resistance: Literature Review and Activities and Findings of the ICEMR NetworkThe interplay between drug resistance and fitness in malaria parasitesPfCRT and its role in antimalarial drug resistanceSelection of drug resistance-mediating Plasmodium falciparum genetic polymorphisms by seasonal malaria chemoprevention in Burkina FasoTemporal trends in prevalence of Plasmodium falciparum drug resistance alleles over two decades of changing antimalarial policy in coastal KenyaIntermittent preventive treatment of malaria provides substantial protection against malaria in children already protected by an insecticide-treated bednet in Burkina Faso: a randomised, double-blind, placebo-controlled trialChloroquine is grossly under dosed in young children with malaria: implications for drug resistanceMolecular Mechanisms for Drug Hypersensitivity Induced by the Malaria Parasite's Chloroquine Resistance TransporterEvolution of Fitness Cost-Neutral Mutant PfCRT Conferring P. falciparum 4-Aminoquinoline Drug Resistance Is Accompanied by Altered Parasite Metabolism and Digestive Vacuole PhysiologyDiversity of T cell epitopes in Plasmodium falciparum circumsporozoite protein likely due to protein-protein interactions.Impact of RTS,S/AS02(A) and RTS,S/AS01(B) on genotypes of P. falciparum in adults participating in a malaria vaccine clinical trial.No seasonal accumulation of resistant P. falciparum when high-dose chloroquine is used.Dynamics of pfcrt alleles CVMNK and CVIET in chloroquine-treated Sudanese patients infected with Plasmodium falciparum.Patterns of chloroquine use and resistance in sub-Saharan Africa: a systematic review of household survey and molecular data.The dynamics of mutations associated with anti-malarial drug resistance in Plasmodium falciparumDifferential prevalence of transporter polymorphisms in symptomatic and asymptomatic falciparum malaria infections in Uganda.Five-year tracking of Plasmodium falciparum allele frequencies in a holoendemic area with indistinct seasonal transitions.Directional selection at the pfmdr1, pfcrt, pfubp1, and pfap2mu loci of Plasmodium falciparum in Kenyan children treated with ACT.Chemotherapy, within-host ecology and the fitness of drug-resistant malaria parasitesEvidence that mutant PfCRT facilitates the transmission to mosquitoes of chloroquine-treated Plasmodium gametocytesClinical trial of extended-dose chloroquine for treatment of resistant falciparum malaria among Afghan refugees in Pakistan.Temporal and seasonal changes of genetic polymorphisms associated with altered drug susceptibility to chloroquine, lumefantrine, and quinine in Guinea-Bissau between 2003 and 2012The fitness of drug-resistant malaria parasites in a rodent model: multiplicity of infectionGenome-wide transcriptome profiling reveals functional networks involving the Plasmodium falciparum drug resistance transporters PfCRT and PfMDR1Balancing drug resistance and growth rates via compensatory mutations in the Plasmodium falciparum chloroquine resistance transporter.Evolutionary biology and the avoidance of antimicrobial resistance.Mutations in the Plasmodium falciparum chloroquine resistance transporter, PfCRT, enlarge the parasite's food vacuole and alter drug sensitivities.Serology describes a profile of declining malaria transmission in Farafenni, The GambiaRational deployment of antimalarial drugs in Africa: should first-line combination drugs be reserved for paediatric malaria cases?Longitudinal study assessing the return of chloroquine susceptibility of Plasmodium falciparum in isolates from travellers returning from West and Central Africa, 2000-2011Heterogeneous distribution of Plasmodium falciparum drug resistance haplotypes in subsets of the host population.Reduction of transmission from malaria patients by artemisinin combination therapies: a pooled analysis of six randomized trialsCombinatorial Genetic Modeling of pfcrt-Mediated Drug Resistance Evolution in Plasmodium falciparum.Chloroquine is grossly overdosed and overused but well tolerated in Guinea-bissau.Fitness Consequences of Plasmodium falciparum pfmdr1 Polymorphisms Inferred from Ex Vivo Culture of Ugandan ParasitesCulture-adapted Plasmodium falciparum isolates from UK travellers: in vitro drug sensitivity, clonality and drug resistance markers.Selection for chloroquine-sensitive Plasmodium falciparum by wild Anopheles arabiensis in Southern Zambia.Impaired fitness of drug-resistant malaria parasites: evidence and implication on drug-deployment policies.Changes in malaria parasite drug resistance in an endemic population over a 25-year period with resulting genomic evidence of selection.
P2860
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P2860
Seasonal carriage of pfcrt and pfmdr1 alleles in Gambian Plasmodium falciparum imply reduced fitness of chloroquine-resistant parasites.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Seasonal carriage of pfcrt and ...... loroquine-resistant parasites.
@en
Seasonal carriage of pfcrt and ...... loroquine-resistant parasites.
@nl
type
label
Seasonal carriage of pfcrt and ...... loroquine-resistant parasites.
@en
Seasonal carriage of pfcrt and ...... loroquine-resistant parasites.
@nl
prefLabel
Seasonal carriage of pfcrt and ...... loroquine-resistant parasites.
@en
Seasonal carriage of pfcrt and ...... loroquine-resistant parasites.
@nl
P2093
P2860
P921
P356
P1476
Seasonal carriage of pfcrt and ...... loroquine-resistant parasites.
@en
P2093
Christopher J Drakeley
Colin J Sutherland
Geoffrey Targett
Musa Jawara
Neal Alexander
Rachel Hallett
Rosalynn Ord
P2860
P304
P356
10.1086/522154
P407
P577
2007-10-25T00:00:00Z