Pretubulysin derived probes as novel tools for monitoring the microtubule network via activity-based protein profiling and fluorescence microscopy.
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Advancing understanding of microbial bioenergy conversion processes by activity-based protein profilingChemical proteomics approaches for identifying the cellular targets of natural productsPretubulysin: a new option for the treatment of metastatic cancer.A small molecule inhibits protein disulfide isomerase and triggers the chemosensitization of cancer cells.Chemistry and biology of tubulysins: antimitotic tetrapeptides with activity against drug resistant cancers.Making a Long Journey Short: Alkyne Functionalization of Natural Product Scaffolds.Target identification with quantitative activity based protein profiling (ABPP).Synthesis and structure-activity relationship studies of novel tubulysin U analogues--effect on cytotoxicity of structural variations in the tubuvaline fragment.Target discovery of acivicin in cancer cells elucidates its mechanism of growth inhibition†Electronic supplementary information (ESI) available: Synthesis, cloning, protein expression, purification and biochemical assays. See DOI: 10.1039/c4sc02339kChemical Proteomics Identifies SLC25A20 as a Functional Target of the Ingenol Class of Actinic Keratosis Drugs.Alkynol natural products target ALDH2 in cancer cells by irreversible binding to the active site.Target profiling of 4-hydroxyderricin in S. aureus reveals seryl-tRNA synthetase binding and inhibition by covalent modification.Copper-assisted click reactions for activity-based proteomics: fine-tuned ligands and refined conditions extend the scope of application.
P2860
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P2860
Pretubulysin derived probes as novel tools for monitoring the microtubule network via activity-based protein profiling and fluorescence microscopy.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Pretubulysin derived probes as ...... g and fluorescence microscopy.
@en
Pretubulysin derived probes as ...... g and fluorescence microscopy.
@nl
type
label
Pretubulysin derived probes as ...... g and fluorescence microscopy.
@en
Pretubulysin derived probes as ...... g and fluorescence microscopy.
@nl
prefLabel
Pretubulysin derived probes as ...... g and fluorescence microscopy.
@en
Pretubulysin derived probes as ...... g and fluorescence microscopy.
@nl
P2093
P2860
P356
P1433
P1476
Pretubulysin derived probes as ...... g and fluorescence microscopy.
@en
P2093
Angelika Ullrich
Angelika Vollmar
Georg C Rudolf
Jens L Burkhart
Jürgen Eirich
Stefan Zahler
Stephan A Sieber
Uli Kazmaier
P2860
P304
P356
10.1039/C2MB25144B
P577
2012-06-21T00:00:00Z