Novel synthetic derivatives of the natural product berbamine inhibit Jak2/Stat3 signaling and induce apoptosis of human melanoma cells.
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A novel berbamine derivative inhibits cell viability and induces apoptosis in cancer stem-like cells of human glioblastoma, via up-regulation of miRNA-4284 and JNK/AP-1 signalingDihydroartemisinin as a Putative STAT3 Inhibitor, Suppresses the Growth of Head and Neck Squamous Cell Carcinoma by Targeting Jak2/STAT3 SignalingTherapeutic modulators of STAT signalling for human diseasesTargeting constitutively-activated STAT3 in hypoxic ovarian cancer, using a novel STAT3 inhibitorNovel harmine derivatives for tumor targeted therapy.Glucose-6-phosphate dehydrogenase and NADPH oxidase 4 control STAT3 activity in melanoma cells through a pathway involving reactive oxygen species, c-SRC and SHP2.Lentiginoses in polycythemia vera patient: Is there a role for JAK2 (V617F) mutation?Identification of a natural product-like STAT3 dimerization inhibitor by structure-based virtual screening.A natural product-like JAK2/STAT3 inhibitor induces apoptosis of malignant melanoma cells.Berbamine inhibits the growth of liver cancer cells and cancer-initiating cells by targeting Ca²⁺/calmodulin-dependent protein kinase II.A novel synthetic derivative of the natural product berbamine inhibits cell viability and induces apoptosis of human osteosarcoma cells, associated with activation of JNK/AP-1 signaling.Natural products and their derivatives regulating the janus kinase/signal transducer and activator of transcription pathway.4-Chlorbenzoyl Berbamine, a Novel Derivative of the Natural Product Berbamine, Potently Inhibits the Growth of Human Myeloma Cells by Modulating the NF-κB and JNK Signalling Pathways.Salidroside reduces renal cell carcinoma proliferation by inhibiting JAK2/STAT3 signaling.Anticancer effect of salidroside on colon cancer through inhibiting JAK2/STAT3 signaling pathway.A sesquiterpene lactone antrocin from Antrodia camphorata negatively modulates JAK2/STAT3 signaling via microRNA let-7c and induces apoptosis in lung cancer cells.Curcumin analogue, A13, exhibits anti-leukemia effect via inhibiting STAT3.Cucurbitacin B inhibits cell proliferation and induces apoptosis in human osteosarcoma cells via modulation of the JAK2/STAT3 and MAPK pathwaysSynergistic Antitumor Effects of Berbamine and Paclitaxel through ROS/Akt Pathway in Glioma Cells.Berbamine inhibited the growth of prostate cancer cells in vivo and in vitro via triggering intrinsic pathway of apoptosis.Stabilization of the c-Myc Protein by CAMKIIγ Promotes T Cell Lymphoma.The JAK2/STAT3 pathway is involved in the anti-melanoma effects of atractylenolide I.Berbamine induces SMMC-7721 cell apoptosis via upregulating p53, downregulating survivin expression and activating mitochondria signaling pathway.Role of Non Receptor Tyrosine Kinases in Hematological Malignances and its Targeting by Natural Products.Cardiotoxicity evaluation of nine alkaloids from Rhizoma Coptis.4-parvifuran inhibits metastatic and invasive actions through the JAK2/STAT3 pathway in osteosarcoma cells.In vitro and in vivo metabolic activation of berbamine to quinone methide intermediate.
P2860
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P2860
Novel synthetic derivatives of the natural product berbamine inhibit Jak2/Stat3 signaling and induce apoptosis of human melanoma cells.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Novel synthetic derivatives of ...... tosis of human melanoma cells.
@en
Novel synthetic derivatives of ...... tosis of human melanoma cells.
@nl
type
label
Novel synthetic derivatives of ...... tosis of human melanoma cells.
@en
Novel synthetic derivatives of ...... tosis of human melanoma cells.
@nl
prefLabel
Novel synthetic derivatives of ...... tosis of human melanoma cells.
@en
Novel synthetic derivatives of ...... tosis of human melanoma cells.
@nl
P2093
P2860
P1433
P1476
Novel synthetic derivatives of ...... tosis of human melanoma cells.
@en
P2093
Angela Perkins
David A Horne
Richard Jove
Rong-Zhen Xu
Sangkil Nam
Wendong Huang
P2860
P304
P356
10.1016/J.MOLONC.2012.05.002
P577
2012-06-02T00:00:00Z