MDM2 expression is repressed by the RNA-binding protein RNPC1 via mRNA stability.
about
Backbone-independent nucleic acid binding by splicing factor SUP-12 reveals key aspects of molecular recognitionRNA-binding protein RNPC1: acting as a tumor suppressor in breast cancer.Mice deficient in Rbm38, a target of the p53 family, are susceptible to accelerated aging and spontaneous tumors.The RNA binding protein RBM38 (RNPC1) regulates splicing during late erythroid differentiation.Comparative genome-wide association studies of a depressive symptom phenotype in a repeated measures setting by race/ethnicity in the Multi-Ethnic Study of Atherosclerosis.Estrogen receptor (ER) was regulated by RNPC1 stabilizing mRNA in ER positive breast cancer.PPM1D phosphatase, a target of p53 and RBM38 RNA-binding protein, inhibits p53 mRNA translation via dephosphorylation of RBM38.The impact of post-transcriptional regulation in the p53 network.Rbm24, an RNA-binding protein and a target of p53, regulates p21 expression via mRNA stability.RNPC1 enhances progesterone receptor functions by regulating its mRNA stability in breast cancer.The role of c-Myc-RBM38 loop in the growth suppression in breast cancer.Hypoxia-inducible factor 1 alpha is regulated by RBM38, a RNA-binding protein and a p53 family target, via mRNA translation.Knockdown of Sec8 promotes cell-cycle arrest at G1/S phase by inducing p21 via control of FOXO proteins.Glycogen synthase kinase 3 promotes p53 mRNA translation via phosphorylation of RNPC1.Modulation of the p53 family network by RNA-binding proteins.PTEN expression is upregulated by a RNA-binding protein RBM38 via enhancing its mRNA stability in breast cancer.Regulation of Mdm2 mRNA stability by RNA-binding protein RNPC1.RBM38 is involved in TGF-β-induced epithelial-to-mesenchymal transition by stabilising zonula occludens-1 mRNA in breast cancer.RBM38 plays a tumor-suppressor role via stabilizing the p53-mdm2 loop function in hepatocellular carcinoma
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P2860
MDM2 expression is repressed by the RNA-binding protein RNPC1 via mRNA stability.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
MDM2 expression is repressed by the RNA-binding protein RNPC1 via mRNA stability.
@en
MDM2 expression is repressed by the RNA-binding protein RNPC1 via mRNA stability.
@nl
type
label
MDM2 expression is repressed by the RNA-binding protein RNPC1 via mRNA stability.
@en
MDM2 expression is repressed by the RNA-binding protein RNPC1 via mRNA stability.
@nl
prefLabel
MDM2 expression is repressed by the RNA-binding protein RNPC1 via mRNA stability.
@en
MDM2 expression is repressed by the RNA-binding protein RNPC1 via mRNA stability.
@nl
P2093
P2860
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MDM2 expression is repressed by the RNA-binding protein RNPC1 via mRNA stability.
@en
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P356
10.1038/ONC.2012.238
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P577
2012-06-18T00:00:00Z
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P6179
1020457042