GRP78 regulates clusterin stability, retrotranslocation and mitochondrial localization under ER stress in prostate cancer.
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Non-secreted clusterin isoforms are translated in rare amounts from distinct human mRNA variants and do not affect Bax-mediated apoptosis or the NF-κB signaling pathwayThe co-chaperone DNAJC12 binds to Hsc70 and is upregulated by endoplasmic reticulum stressClusterin facilitates stress-induced lipidation of LC3 and autophagosome biogenesis to enhance cancer cell survivalBioinformatics analysis of differentially expressed proteins in prostate cancer based on proteomics dataRaf/MEK/ERK can regulate cellular levels of LC3B and SQSTM1/p62 at expression levelsClusterin protects hepatocellular carcinoma cells from endoplasmic reticulum stress induced apoptosis through GRP78.The duration of gastrin treatment affects global gene expression and molecular responses involved in ER stress and anti-apoptosis.Relationship of clusterin with renal inflammation and fibrosis after the recovery phase of ischemia-reperfusion injuryUnfolded protein response plays a critical role in heart damage after myocardial ischemia/reperfusion in ratsInhibition of endoplasmic reticulum chaperone protein glucose-regulated protein 78 potentiates anti-angiogenic therapy in renal cell carcinoma through inactivation of the PERK/eIF2α pathway.Mitochondrial ATAD3A combines with GRP78 to regulate the WASF3 metastasis-promoting protein.Targeting heat shock proteins in metastatic castration-resistant prostate cancer.The CLU-files: disentanglement of a mystery.Heat shock proteins in hepatocellular carcinoma: Molecular mechanism and therapeutic potential.Requirement of clusterin expression for prosurvival autophagy in hypoxic kidney tubular epithelial cells.Oncogenic and oncosuppressive signal transduction at mitochondria-associated endoplasmic reticulum membranesClusterin as a therapeutic target.Glucose-regulated protein 78 mediates hormone-independent prostate cancer progression and metastasis through maspin and COX-2 expression.Clusterin knockdown sensitizes prostate cancer cells to taxane by modulating mitosis.miR-30d, miR-181a and miR-199a-5p cooperatively suppress the endoplasmic reticulum chaperone and signaling regulator GRP78 in cancer.Expression and purification of chaperone-active recombinant clusterin.Transcriptome-Based Analysis of Molecular Pathways for Clusterin Functions in Kidney Cells.Exposure of vital cells to necrotic cell lysates induce the IRE1α branch of the unfolded protein response and cell proliferation.Protective effect of clusterin on rod photoreceptor in rat model of retinitis pigmentosaBisoprolol protects myocardium cells against ischemia/reperfusion injury by attenuating unfolded protein response in rats.Serum differential protein identification of Xinjiang Kazakh esophageal cancer patients based on the two-dimensional liquid-phase chromatography and LTQ MS.Propofol attenuates H2O2-induced oxidative stress and apoptosis via the mitochondria- and ER-medicated pathways in neonatal rat cardiomyocytes.Role of NADPH oxidase in the regulation of autophagy in cardiomyocytes.Clusterin protects neurons against intracellular proteotoxicity.Calcitriol Inhibits HCV Infection via Blockade of Activation of PPAR and Interference with Endoplasmic Reticulum-Associated Degradation.Silencing clusterin gene transcription on effects of multidrug resistance reversing of human hepatoma HepG2/ADM cells.4-Phenyl butyric acid prevents glucocorticoid-induced osteoblast apoptosis by attenuating endoplasmic reticulum stress.Dexmedetomidine attenuates H2O2-induced neonatal rat cardiomyocytes apoptosis through mitochondria- and ER-medicated oxidative stress pathways.Role of Mitochondria-Associated ER Membranes in Calcium Regulation in Cancer-Specific Settings.Gastrodin alleviates glucocorticoid induced osteoporosis in rats via activating the Nrf2 signaling pathways.
P2860
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P2860
GRP78 regulates clusterin stability, retrotranslocation and mitochondrial localization under ER stress in prostate cancer.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
GRP78 regulates clusterin stab ...... ER stress in prostate cancer.
@en
GRP78 regulates clusterin stab ...... ER stress in prostate cancer.
@nl
type
label
GRP78 regulates clusterin stab ...... ER stress in prostate cancer.
@en
GRP78 regulates clusterin stab ...... ER stress in prostate cancer.
@nl
prefLabel
GRP78 regulates clusterin stab ...... ER stress in prostate cancer.
@en
GRP78 regulates clusterin stab ...... ER stress in prostate cancer.
@nl
P2093
P2860
P356
P1433
P1476
GRP78 regulates clusterin stab ...... ER stress in prostate cancer.
@en
P2093
P2860
P2888
P304
P356
10.1038/ONC.2012.212
P407
P577
2012-06-11T00:00:00Z