The checkpoint kinase inhibitor AZD7762 potentiates chemotherapy-induced apoptosis of p53-mutated multiple myeloma cells.
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DNA Damage Signalling and Repair Inhibitors: The Long-Sought-After Achilles' Heel of CancerDNA damage response and prostate cancer: defects, regulation and therapeutic implicationsTargeting Ongoing DNA Damage in Multiple Myeloma: Effects of DNA Damage Response Inhibitors on Plasma Cell Survival.Development of synthetic lethality anticancer therapeutics.Enhancer of rudimentary homolog regulates DNA damage response in hepatocellular carcinomaConstitutive activation of the DNA damage response pathway as a novel therapeutic target in diffuse large B-cell lymphomaIn vitro and in vivo single-agent efficacy of checkpoint kinase inhibition in acute lymphoblastic leukemiaDownregulation of MicroRNA-152 contributes to high expression of DKK1 in multiple myelomaChemotherapy induced DNA damage response: convergence of drugs and pathwaysDNA repair pathways in human multiple myeloma: role in oncogenesis and potential targets for treatment.Kinase inhibitors as potential agents in the treatment of multiple myeloma.DNA replication stress and cancer: cause or cure?Family-wide Structural Analysis of Human Numb-Associated Protein Kinases.The cell cycle checkpoint inhibitors in the treatment of leukemias.Aven-mediated checkpoint kinase control regulates proliferation and resistance to chemotherapy in conventional osteosarcoma.Bendamustine and melphalan kill myeloma cells similarly through reactive oxygen species production and activation of the p53 pathway and do not overcome resistance to each other.Unprecedently Large-Scale Kinase Inhibitor Set Enabling the Accurate Prediction of Compound-Kinase Activities: A Way toward Selective Promiscuity by Design?The G2 checkpoint-a node-based molecular switch.Checkpoint kinase 1 expression is an adverse prognostic marker and therapeutic target in MYC-driven medulloblastomaManipulating DNA damage-response signaling for the treatment of immune-mediated diseases.ATR/CHK1 inhibitors and cancer therapy.Acetyl-macrocalin B, an ent-kaurane diterpenoid, initiates apoptosis through the ROS-p38-caspase 9-dependent pathway and induces G2/M phase arrest via the Chk1/2-Cdc25C-Cdc2/cyclin B axis in non-small cell lung cancer.
P2860
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P2860
The checkpoint kinase inhibitor AZD7762 potentiates chemotherapy-induced apoptosis of p53-mutated multiple myeloma cells.
description
2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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name
The checkpoint kinase inhibito ...... utated multiple myeloma cells.
@en
The checkpoint kinase inhibito ...... utated multiple myeloma cells.
@nl
type
label
The checkpoint kinase inhibito ...... utated multiple myeloma cells.
@en
The checkpoint kinase inhibito ...... utated multiple myeloma cells.
@nl
prefLabel
The checkpoint kinase inhibito ...... utated multiple myeloma cells.
@en
The checkpoint kinase inhibito ...... utated multiple myeloma cells.
@nl
P2093
P1476
The checkpoint kinase inhibito ...... utated multiple myeloma cells.
@en
P2093
Gary K Schwartz
Heather J Landau
Hillel Friedman
Jayasree S Nair
Raymond L Comenzo
Samuel C McNeely
Stephen D Nimer
Suresh C Jhanwar
Takashi Asai
P304
P356
10.1158/1535-7163.MCT-11-0949
P577
2012-05-31T00:00:00Z