Regulation of tumor suppressor p53 and HCT116 cell physiology by histone demethylase JMJD2D/KDM4D.
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The role of histone demethylases in cancer therapyKDM4/JMJD2 histone demethylases: epigenetic regulators in cancer cellsKDM4B/JMJD2B is a p53 target gene that modulates the amplitude of p53 response after DNA damage.Pro-growth role of the JMJD2C histone demethylase in HCT-116 colon cancer cells and identification of curcuminoids as JMJD2 inhibitors.A polymorphism in JMJD2C alters the cleavage by caspase-3 and the prognosis of human breast cancer.Activation of p53 with ilimaquinone and ethylsmenoquinone, marine sponge metabolites, induces apoptosis and autophagy in colon cancer cellsOverexpression of KDM4 lysine demethylases disrupts the integrity of the DNA mismatch repair pathway.KDM4A, KDM4B and KDM4C in non-small cell lung cancer.ETS variant 1 regulates matrix metalloproteinase-7 transcription in LNCaP prostate cancer cells.Downregulation of Hlx closely related to the decreased expressions of T-bet and Runx3 in patients with gastric cancer may be associated with a pathological event leading to the imbalance of Th1/Th2.Histone demethylase JMJD2A drives prostate tumorigenesis through transcription factor ETV1.ETS transcription factor ERG cooperates with histone demethylase KDM4A.The oncogenic potential of Jumonji D2 (JMJD2/KDM4) histone demethylase overexpression.The roles of Jumonji-type oxygenases in human disease.Histone Modifications and Cancer.Crosstalk between epigenetics and metabolism-Yin and Yang of histone demethylases and methyltransferases in cancer.Partial-occupancy binders identified by the Pan-Dataset Density Analysis method offer new chemical opportunities and reveal cryptic binding sites.The emerging role of lysine demethylases in DNA damage response: dissecting the recruitment mode of KDM4D/JMJD2D to DNA damage sitesHistone demethylase JMJD2B and JMJD2C induce fibroblast growth factor 2: mediated tumorigenesis of osteosarcoma.RNA-dependent chromatin localization of KDM4D lysine demethylase promotes H3K9me3 demethylation.KDM4C (GASC1) lysine demethylase is associated with mitotic chromatin and regulates chromosome segregation during mitosis.Kdm4b histone demethylase is a DNA damage response protein and confers a survival advantage following γ-irradiation.Upregulation of PSMD10 caused by the JMJD2A histone demethylase.Identification and characterization of PKF118-310 as a KDM4A inhibitor.Cooperation between ETS variant 2 and Jumonji domain‑containing 2 histone demethylases.KDM5A Regulates a Translational Program that Controls p53 Protein ExpressionA potential common role of the Jumonji C domain-containing 1A histone demethylase and chromatin remodeler ATRX in promoting colon cancer
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Regulation of tumor suppressor p53 and HCT116 cell physiology by histone demethylase JMJD2D/KDM4D.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
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2012年學術文章
@zh-hant
name
Regulation of tumor suppressor ...... tone demethylase JMJD2D/KDM4D.
@en
Regulation of tumor suppressor ...... tone demethylase JMJD2D/KDM4D.
@nl
type
label
Regulation of tumor suppressor ...... tone demethylase JMJD2D/KDM4D.
@en
Regulation of tumor suppressor ...... tone demethylase JMJD2D/KDM4D.
@nl
prefLabel
Regulation of tumor suppressor ...... tone demethylase JMJD2D/KDM4D.
@en
Regulation of tumor suppressor ...... tone demethylase JMJD2D/KDM4D.
@nl
P2093
P2860
P1433
P1476
Regulation of tumor suppressor ...... tone demethylase JMJD2D/KDM4D.
@en
P2093
Ralf Janknecht
Sangphil Oh
Tae-Dong Kim
P2860
P304
P356
10.1371/JOURNAL.PONE.0034618
P407
P577
2012-04-13T00:00:00Z