Enzymic and immunochemical properties of lysozyme. XVI. A novel synthetic approach to an antigenic reactive site by direct linkage of the relevant conformationally adjacent residues constituting the site.
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Enzymic and immunochemical properties of lysozyme. Accurate definition of the antigenic site around the disulphide bridge 30-115 (site 3) by 'surface-simulation' synthesisSUPERFICIAL--surface mapping of proteins via structure-based peptide library design.Design of peptide enzymes (pepzymes): surface-simulation synthetic peptides that mimic the chymotrypsin and trypsin active sites exhibit the activity and specificity of the respective enzyme.Localization, synthesis, and activity of an antigenic site on influenza virus hemagglutinin.Prediction and conformation by synthesis of two antigenic sites in human haemoglobin by extrapolation from the known antigenic structure of sperm-whale myoglobin.Determination of the entire antigenic structure of native lysozyme by surface-simulation synthesis, a novel concept in molecular recognition.Antigenic structures of proteins. Their determination has revealed important aspects of immune recognition and generated strategies for synthetic mimicking of protein binding sites.Using THz Spectroscopy, Evolutionary Network Analysis Methods, and MD Simulation to Map the Evolution of Allosteric Communication Pathways in c-Type Lysozymes.Antibody combining sites can be mimicked synthetically. Surface-simulation synthesis of the phosphorylcholine-combining site of myeloma protein M-603Surface-simulation synthesis of the substrate-binding site of an enzyme. Demonstration with trypsinConformation-dependent recognition of a protein by T cells requires presentation without processing.Inhibition of rabbit tissue kininase by anti-(endo-oligopeptidase A) antibodies.The precise and entire antigenic structure of native lysozyme.Localization and verification by synthesis of five antigenic sites of bovine serum albumin.Delineation of the third antigenic site of lysozyme by application of a novel 'surface-simulation' synthetic approach directly linking the conformationally adjacent residues forming the site.Boundary refinement of the lysozyme antigenic site around the disulphide bond 6-127 (site 1) by 'surface-simulation' synthesis.Molecular cartography of globular proteins with application to antigenic sites.Binding with lysozyme of antibodies against surface-simulation peptides representing the lysozyme antigenic sites.Inhibition of phosphorylcholine binding to antibodies using synthetic peptides
P2860
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P2860
Enzymic and immunochemical properties of lysozyme. XVI. A novel synthetic approach to an antigenic reactive site by direct linkage of the relevant conformationally adjacent residues constituting the site.
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1976 nî lūn-bûn
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1976年の論文
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1976年学术文章
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1976年学术文章
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1976年学术文章
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1976年学术文章
@zh-my
1976年学术文章
@zh-sg
1976年學術文章
@yue
1976年學術文章
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1976年學術文章
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name
Enzymic and immunochemical pro ...... esidues constituting the site.
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Enzymic and immunochemical pro ...... esidues constituting the site.
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Enzymic and immunochemical pro ...... esidues constituting the site.
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Enzymic and immunochemical pro ...... esidues constituting the site.
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Enzymic and immunochemical pro ...... esidues constituting the site.
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Enzymic and immunochemical pro ...... esidues constituting the site.
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P2093
P1476
Enzymic and immunochemical pro ...... esidues constituting the site.
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P2093
P304
P356
10.1016/0005-2795(76)90219-1
P577
1976-04-01T00:00:00Z