A human stem cell model of early Alzheimer's disease pathology in Down syndrome.
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Concise review: new paradigms for Down syndrome research using induced pluripotent stem cells: tackling complex human genetic diseaseAnalysis of conditional heterozygous STXBP1 mutations in human neuronsIntracerebral haemorrhage in Down syndrome: protected or predisposed?Induced pluripotent stem cells in Alzheimer's disease: applications for disease modeling and cell-replacement therapyThe amyloid hypothesis of Alzheimer's disease at 25 yearsThe importance of understanding individual differences in Down syndromeThe Application of Human iPSCs in Neurological Diseases: From Bench to BedsideDissecting Alzheimer disease in Down syndrome using mouse modelsCardiovascular Disease Modeling Using Patient-Specific Induced Pluripotent Stem CellsA genetic cause of Alzheimer disease: mechanistic insights from Down syndromeApplications of Induced Pluripotent Stem Cells in Studying the Neurodegenerative DiseasesConcise Review: Methods and Cell Types Used to Generate Down Syndrome Induced Pluripotent Stem CellsAlzheimer's in 3D culture: challenges and perspectivesDrug repositioning approaches for the discovery of new therapeutics for Alzheimer's diseaseDevelopment and function of human cerebral cortex neural networks from pluripotent stem cells in vitro3D culture models of Alzheimer's disease: a road map to a "cure-in-a-dish"The Use of Induced Pluripotent Stem Cell Technology to Advance Autism Research and TreatmentCreating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders.Creation of an open-access, mutation-defined fibroblast resource for neurological disease research.The familial Alzheimer's disease APPV717I mutation alters APP processing and Tau expression in iPSC-derived neurons.Enhanced derivation of human pluripotent stem cell-derived cortical glutamatergic neurons by a small molecule.Stem cell models of Alzheimer's disease: progress and challenges.Role of astroglia in Down's syndrome revealed by patient-derived human-induced pluripotent stem cells.Deficits in human trisomy 21 iPSCs and neurons.Translating dosage compensation to trisomy 21Down's syndrome and Alzheimer's disease: towards secondary prevention.Investigating human disease using stem cell models.Probing the secrets of Alzheimer's disease using human-induced pluripotent stem cell technology.Gene expression analysis of induced pluripotent stem cells from aneuploid chromosomal syndromes.Induced pluripotent stem cell-derived neuronal cells from a sporadic Alzheimer's disease donor as a model for investigating AD-associated gene regulatory networks.N-butylidenephthalide attenuates Alzheimer's disease-like cytopathy in Down syndrome induced pluripotent stem cell-derived neuronsA time course analysis of the electrophysiological properties of neurons differentiated from human induced pluripotent stem cells (iPSCs).Comparison and optimization of hiPSC forebrain cortical differentiation protocols.Cortical neurogenesis from pluripotent stem cells: complexity emerging from simplicity.Elucidating molecular phenotypes caused by the SORL1 Alzheimer's disease genetic risk factor using human induced pluripotent stem cells.Genomics in neurological disorders.Connectivity and circuitry in a dish versus in a brainOpportunities and Limitations of Modelling Alzheimer's Disease with Induced Pluripotent Stem CellsA 3D human neural cell culture system for modeling Alzheimer's disease.Induced pluripotent stem cells to model and treat neurogenetic disorders
P2860
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P2860
A human stem cell model of early Alzheimer's disease pathology in Down syndrome.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
A human stem cell model of early Alzheimer's disease pathology in Down syndrome.
@en
A human stem cell model of early Alzheimer's disease pathology in Down syndrome.
@nl
type
label
A human stem cell model of early Alzheimer's disease pathology in Down syndrome.
@en
A human stem cell model of early Alzheimer's disease pathology in Down syndrome.
@nl
prefLabel
A human stem cell model of early Alzheimer's disease pathology in Down syndrome.
@en
A human stem cell model of early Alzheimer's disease pathology in Down syndrome.
@nl
P2093
P2860
P921
P1476
A human stem cell model of early Alzheimer's disease pathology in Down syndrome.
@en
P2093
Frederick J Livesey
Glenn MacLean
Stuart H Orkin
Yichen Shi
P2860
P304
P356
10.1126/SCITRANSLMED.3003771
P407
P577
2012-02-15T00:00:00Z