Nimbolide, a neem limonoid abrogates canonical NF-κB and Wnt signaling to induce caspase-dependent apoptosis in human hepatocarcinoma (HepG2) cells.
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Therapeutics Role of Azadirachta indica (Neem) and Their Active Constituents in Diseases Prevention and TreatmentAnticancer properties of nimbolide and pharmacokinetic considerations to accelerate its developmentNeem components as potential agents for cancer prevention and treatmentReview on molecular and chemopreventive potential of nimbolide in cancerAdaptive cellular stress pathways as therapeutic targets of dietary phytochemicals: focus on the nervous systemNimbolide upregulates RECK by targeting miR-21 and HIF-1α in cell lines and in a hamster oral carcinogenesis modelEssential oils and their constituents as anticancer agents: a mechanistic view.Proceedings of the Indo-U.S. bilateral workshop on accelerating botanicals/biologics agent development research for cancer chemoprevention, treatment, and survivalThe heparan sulfate mimetic PG545 interferes with Wnt/β-catenin signaling and significantly suppresses pancreatic tumorigenesis alone and in combination with gemcitabineThe Limonoids TS3 and Rubescin E Induce Apoptosis in Human Hepatoma Cell Lines and Interfere with NF-κB SignalingNimbolide, a neem limonoid inhibits Phosphatidyl Inositol-3 Kinase to activate Glycogen Synthase Kinase-3β in a hamster model of oral oncogenesis.Neem oil limonoids induces p53-independent apoptosis and autophagy.Pomegranate Bioactive Constituents Suppress Cell Proliferation and Induce Apoptosis in an Experimental Model of Hepatocellular Carcinoma: Role of Wnt/ β -Catenin Signaling Pathway.Natural Agents Used in Chemoprevention of Aerodigestive and GI CancersNimbolide Inhibits Nuclear Factor-КB Pathway in Intestinal Epithelial Cells and Macrophages and Alleviates Experimental Colitis in Mice.Induction of cell cycle arrest, DNA damage, and apoptosis by nimbolide in human renal cell carcinoma cells.Nimbolide inhibits invasion and migration, and down-regulates uPAR chemokine gene expression, in two breast cancer cell lines.Limonoids from Azadirachta indica var. siamensis extracts and their cytotoxic and melanogenesis-inhibitory activities.Cytotoxic and melanogenesis-inhibitory activities of limonoids from the leaves of Azadirachta indica (Neem).Anti-proliferative and apoptosis inducing effect of nimbolide by altering molecules involved in apoptosis and IGF signalling via PI3K/Akt in prostate cancer (PC-3) cell line.Apoptosis is an obstacle to the differentiation of adipose-derived stromal cells into astrocytes.Ethanolic Neem (Azadirachta indica) Leaf Extract Prevents Growth of MCF-7 and HeLa Cells and Potentiates the Therapeutic Index of Cisplatin.Cipatrijugin G, a new trijugin-type limonoid bearing an uncommon γ-hydroxybutenolide unit from the aerial parts of Cipadessa cinerascens.Nimbolide reduces CD44 positive cell population and induces mitochondrial apoptosis in pancreatic cancer cells.Nimbolide induces apoptosis in human nasopharyngeal cancer cells.Gedunin abrogates aldose reductase, PI3K/Akt/mToR, and NF-κB signaling pathways to inhibit angiogenesis in a hamster model of oral carcinogenesis.Nimbolide, a neem limonoid inhibits cytoprotective autophagy to activate apoptosis via modulation of the PI3K/Akt/GSK-3β signalling pathway in oral cancerlectin alleviates diabetic nephropathy by inhibiting the LOX1/NF-κB/caspase-9 signaling pathwayA Sensitive Liquid Chromatography-Tandem Mass Spectrometry Method for the Determination of Nimbolide in Mouse Serum: Application to a Preclinical Pharmacokinetics Study
P2860
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P2860
Nimbolide, a neem limonoid abrogates canonical NF-κB and Wnt signaling to induce caspase-dependent apoptosis in human hepatocarcinoma (HepG2) cells.
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2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Nimbolide, a neem limonoid abr ...... hepatocarcinoma (HepG2) cells.
@en
Nimbolide, a neem limonoid abr ...... hepatocarcinoma (HepG2) cells.
@nl
type
label
Nimbolide, a neem limonoid abr ...... hepatocarcinoma (HepG2) cells.
@en
Nimbolide, a neem limonoid abr ...... hepatocarcinoma (HepG2) cells.
@nl
prefLabel
Nimbolide, a neem limonoid abr ...... hepatocarcinoma (HepG2) cells.
@en
Nimbolide, a neem limonoid abr ...... hepatocarcinoma (HepG2) cells.
@nl
P2093
P1476
Nimbolide, a neem limonoid abr ...... hepatocarcinoma (HepG2) cells.
@en
P2093
Abhishek Kumar Singh
Devarajan Karunagaran
Gempuraj Purushothaman
Krishnamurthy Kavitha
Krishnan Ramalingam
Prabukumar Anitha
Ramamurthi Vidya Priyadarsini
Ramasamy Sakthivel
Siddavaram Nagini
P356
10.1016/J.EJPHAR.2012.01.024
P407
P577
2012-01-31T00:00:00Z